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Alcohol Dehydrogenase

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Definition: A zinc-containing enzyme which oxidizes primary and secondary alcohols or hemiacetals in the presence of NAD. In alcoholic fermentation, it catalyzes the final step of reducing an aldehyde to an alcohol in the presence of NADH and hydrogen.  a specific enzyme; do not confuse with ALCOHOL OXIDOREDUCTASES    Other names Oxidoreductase, Alcohol-NAD+; Dehydrogenase, Yeast Alcohol; Dehydrogenase, Alcohol; Alcohol NAD+ Oxidoreductase; Alcohol Dehydrogenase, Yeast; Yeast Alcohol Dehydrogenase; Alcohol-NAD+ Oxidoreductase; Alcohol Dehydrogenase II; Alcohol Dehydrogenase I; Alcohol Dehydrogenase (NAD+)
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
dihydroxypropanesulfonate 3-dehydrogenase, Cupriavidus pinatubonensis  EC 1.1.1.1   *Alcohol Dehydrogenase *Bacterial Proteins. Microbiology. 2010 May;156(Pt 5):1556-64
ADH7 protein, human  EC 1.1.1.1   *Alcohol Dehydrogenase. Hum Mol Genet 2008 Jan 15;17(2):179-89
ADH3 protein, S cerevisiae  EC 1.1.1.1   *Alcohol Dehydrogenase *Saccharomyces cerevisiae Proteins. Gene 1990 May 31;90(1):79-85
ADH1 protein, S cerevisiae  EC 1.1.1.1   *Alcohol Dehydrogenase *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1985 Nov;5(11):3024-34
ADH2 protein, S cerevisiae  EC 1.1.1.1   *Alcohol Dehydrogenase *Saccharomyces cerevisiae Proteins. Mol Microbiol 2006 Mar;59(5):1531-41
ADH1B protein, human  EC 1.1.1.1   *Alcohol Dehydrogenase. Pharmacogenetics 2003 Apr;13(4):225-30
PTGR2 protein, human  EC 1.1.1.1   *Alcohol Dehydrogenase. Cytogenet Genome Res 2003;103(1-2):79-83
alcohol dehydrogenase 8  EC 1.1.1.-   *Alcohol Dehydrogenase. J Mol Biol. 2003 Jun 27;330(1):75-85
ADH7 protein, S cerevisiae  EC 1.1.1.1   *Alcohol Dehydrogenase *Saccharomyces cerevisiae Proteins. Eur J Biochem 2002 Nov;269(22):5738-45
Adh7 protein, mouse  EC 1.1.1.1   *Alcohol Dehydrogenase. Proc Natl Acad Sci U S A 2002 Apr 16;99(8):5337-42
ADH6 protein, S cerevisiae  EC 1.1.1.2   *Alcohol Dehydrogenase *Saccharomyces cerevisiae Proteins. Biochem J 2002 Jan 1;361(Pt 1):163-72
ADH1C protein, human  EC 1.1.1.1   *Alcohol Dehydrogenase. N Engl J Med 2001 Feb 22;344(8):549-55
alcohol dehydrogenase IV  EC 1.1.1.1   *Alcohol Dehydrogenase. Adv Exp Med Biol 1997;414:357-64
N-formylpiperidine  2591-86-8   *Piperidines Alcohol Dehydrogenase/antagonists & inhibitors. Biochemistry 1997 Mar 25;36(12):3522-7
N-cyclohexylformamide  766-93-8   *Formamides Alcohol Dehydrogenase/antagonists & inhibitors. Biochemistry 1997 Mar 25;36(12):3522-7
4-sulfobenzyl alcohol dehydrogenase  EC 1.1.1.-   *Alcohol Dehydrogenase. J Bacteriol 1997 Feb;179(3):919-27
3-butylthiolane 1-oxide  0   *Sulfhydryl Compounds Alcohol Dehydrogenase/antagonists & inhibitors. Biochemistry 1997 Jan 14;36(2):382-9
Bli-4 protein, Neurospora  EC 1.1.1.1   *Alcohol Dehydrogenase *Fungal Proteins. Mol Gen Genet 1996 Sep 13;252(3):223-9
GbsB protein, Bacillus subtilis  EC 1.1.1.1   *Alcohol Dehydrogenase *Bacterial Proteins. J Bacteriol 1996 Sep;178(17):5121-9
MoaE protein, Klebsiella aerogenes  EC 1.1.1.1   *Alcohol Dehydrogenase *Bacterial Proteins. Gene 1995 Oct 16;164(1):89-94
ADH3b protein, Lycopersicon esculentum  EC 1.1.1.1   *Alcohol Dehydrogenase *Plant Proteins. Plant Mol Biol 1994 Dec;26(6):1875-91
ADH3a protein, Lycopersicon esculentum  EC 1.1.1.1   *Alcohol Dehydrogenase *Plant Proteins. Plant Mol Biol 1994 Dec;26(6):1875-91
ADH protein, Drosophila  EC 1.1.1.1   *Alcohol Dehydrogenase *Drosophila Proteins. Biochem Int 1991 Dec;25(5):879-85
adhE protein, E coli  EC 1.1.1.1   *Alcohol Dehydrogenase *Aldehyde Oxidoreductases *Escherichia coli Proteins. FEBS Lett 1991;281(1-2):59
deslorelin  70235-53-9   Triptorelin Pamoate/*analogs & derivatives Alcohol Dehydrogenase/antagonists & inhibitors.
Pharma Action Enzyme Inhibitors 		Cell Mol Biol 1990;36(3):291
4-pyrazolylbutylisothiourea  91918-09-1   *Pyrazoles Thiourea/*analogs & derivatives Alcohol Dehydrogenase/antagonists & inhibitors. J Mol Biol 1987;197(4):685
1,3-propanediol dehydrogenase  EC 1.1.1.202   *Alcohol Dehydrogenase. J Bacteriol 1987;169(5):2050
N-(4-butoxybenzyl)formamide  87578-63-0 Formamide, N-((4-butoxyphenyl)methyl)  *Formamides Alcohol Dehydrogenase/antagonists & inhibitors. Alcoholism (NY) 1983;7(3):264
4-butoxyphenylacetamide  3413-59-0   *Acetamides Alcohol Dehydrogenase/antagonists & inhibitors. Alcoholism (NY) 1983;7(3):264
pyrazole  288-13-1   *Pyrazoles Alcohol Dehydrogenase/antagonists & inhibitors.
Pharma Action Enzyme Inhibitors 		Gen Comp Endocrinol 1981;45(2):279

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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