Definition: An enzyme that, in the presence of ATP and COENZYME A, catalyzes the cleavage of citrate to yield acetyl CoA, oxaloacetate, ADP, and ORTHOPHOSPHATE. This reaction represents an important step in fatty acid biosynthesis. This enzyme was formerly listed as EC 4.1.3.8.
Other names Citrate Cleavage Enzyme; ATP Citrate Synthase; ATP Citrate Lyase; Synthase, ATP Citrate; Lyase, ATP-Dependent Citrate; Lyase, ATP Citrate; Cleavage Enzyme, Citrate; Citrate Synthase, ATP; Citrate Lyase, ATP-Dependent; Citrate Lyase, ATP; ATP Dependent Citrate Lyase; ATP-Dependent Citrate Lyase; ATP Citrate (pro-3S)-Lyase