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ψ
Aconitate Hydratase
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Definition
: An enzyme that catalyzes the reversible hydration of cis-aconitate to yield citrate or isocitrate. It is one of the citric acid cycle enzymes. EC 4.2.1.3.
Examples
Iron Regulatory Protein 1
;
Iron Regulatory Protein 2
Other names
Isocitrate Hydro-
Lyase; Citrate Hydro-
Lyase; Aconitase; Isocitrate Hydro Lyase; Hydrolyase, Citrate; Hydro-
Lyase, Isocitrate; Hydro-
Lyase, Citrate; Hydratase, Aconitate; Citrate Hydro Lyase; Citrate Hydrolyase
Substance
CAS Registry & name
Categories
Source
Drugs
*
aconitase 2, mouse
EC 4.2.1.3.
*Aconitate Hydratase.
Proteome Res. 2009 Jul;8(7):3252-64
IRPa protein, Plasmodium falciparum
EC 4.2.1.3
*Aconitate Hydratase
*Iron-Regulatory Proteins
Membrane Proteins
RNA-Binding Proteins
Mitochondrial Proteins.
Mol Biochem Parasitol 2005 Sep;143(1):29-38
ACO2 protein, human
EC 4.2.1.3
*Aconitate Hydratase.
J Med Genet 2003 May;40(5);e73
RpfA protein, bacteria
EC 4.2.1.3
*Aconitate Hydratase
*Bacterial Proteins.
Mol Plant Microbe Interact 1997 Apr;10(3):407-15
ACN protein, Legionella pneumophila
EC 4.2.1.3
*Aconitate Hydratase
*Bacterial Proteins.
J Bacteriol 1993 Sep;175(17):5666-76
2,2-
difluorocitric acid
139182-83-5
*Citrates
Aconitate Hydratase/antagonists & inhibitors
ATP Citrate (pro-S)-Lyase/antagonists & inhibitors.
Eur J Biochem 1991;202(3):889