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Carbachol

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Definition: A slowly hydrolyzed cholinergic agonist that acts at both muscarinic and nicotinic receptors.     
Pharmacological Action Analgesics, Non-Narcotic; Cardiotonic Agents; Cholinergic Agonists; Miotics 		Other names Carbamylcholine; Doryl; Carbachol, Isopto; Optopics Brand of Carbachol; NutraMax Brand of Carbachol; Novartis Brand of Carbachol; Miostat; Merck Brand of Carbachol; Mann Brand of Carbachol; Jestryl; Isopto Carbachol; Chauvin Brand of Carbachol; Carboptic; Carbocholine; Carbastat; Carbamoylcholine; Carbamann; Carbacholine; Bipharma Brand of Carbachol; Bioniche Brand of CarbacholDrugs* : MIOSTAT; CARBASTAT; CARBACHOL
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-((alpha-carboxy)-2-nitrobenzyl)carbamoylcholine trifluoroacetate  0   Carbachol/*analogs & derivatives Trifluoroacetic Acid/*analogs & derivatives. Proc Natl Acad Sci U S A 1994 Jul 5;91(14):6629-33
dimethylthionocarbamylcholine  139264-97-4   Carbachol/*analogs & derivatives Ion Channels. J Biomol Struct Dyn 1991 Dec;9(3):489-509
N-(alpha-carboxy-2-nitrobenzyl)carbamoylcholine  117121-25-2   Carbachol/*analogs & derivatives. Biochemistry 1989;28(1):49
N-methylcarbamylcholine  14721-69-8   Carbachol/*analogs & derivatives Ligands. Eur J Pharmacol 1987;139(3):323
EW 1  29739-76-2 N,N,N-trimethyl-2-((((4-(phenylazo)phenyl)amino)carbon yl)oxy)ethanaminium, iodide  Carbachol/*analogs & derivatives. Nature 280(5722):509;1979
N-demethylcarbachol  4220-32-0 Carbamic acid, 2-(dimethylamino)ethyl ester  Carbachol/*analogs & derivatives. J Pharm Sci 1980;69(3):332; J Pharm Sci 67(4):531;1978
hexacarbacholine bromide  306-41-2 choline bromide hexamethylenedicarbamate /OD/ imbretil /OD/ carbolonium bromide  Carbachol/*analogs & derivatives. Pharmacol Biochem Behav 8(4):357;1978; Prakt Anaesth 13(5):398;1978
dimethylcarbamylcholine  14721-70-1   Carbachol/*analogs & derivatives. Mol Pharmacol 7(2):129;1971

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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