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Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing)

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Definition: An enzyme that catalyzes the formation of carbamoyl phosphate from ATP, carbon dioxide, and glutamine. This enzyme is important in the de novo biosynthesis of pyrimidines. EC 6.3.5.5.  DF: GLUTAMINE CP SYNTHASE    Other names Carbamyl Phosphate Synthase (Glutamine); Synthetase II, Carbamoylphosphate; Carbamyl-Phosphate Synthase (Glutamine); Carbamyl Phosphate Synthase II; Carbamoylphosphate Synthetase II; Carbamoyl-Phosphate Synthase (Glutamine)
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
CPA1 protein, S cerevisiae  EC 6.3.5.5   *Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) *Saccharomyces cerevisiae Proteins. J Biol Chem 1999 Dec 31;274(53):37565-74
URA2 protein, S cerevisiae  0   *Aspartate Carbamoyltransferase *Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) *Saccharomyces cerevisiae Proteins. FEBS Lett 1998 Jan 30;422(2):170-4
CAD trifunctional enzyme  0   *Aspartate Carbamoyltransferase *Dihydroorotase *Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) Neoplasm Proteins. Cell 1981;27(2)267
carbamoyl phosphate synthase-aspartatecarbamoyl transferase complex  0   *Aspartate Carbamoyltransferase *Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing). Mol Gen Genet 161(3):297;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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