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Chromosomal Proteins, Non-Histone

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Definition: Nucleoproteins, which in contrast to HISTONES, are acid insoluble. They are involved in chromosomal functions; e.g. they bind selectively to DNA, stimulate transcription resulting in tissue-specific RNA synthesis and undergo specific changes in response to various hormones or phytomitogens.     
Examples Centromere Protein B; High Mobility Group Proteins; Methyl-CpG-Binding Protein 2; Telomere-Binding Proteins 		Other names Non-Histone Chromosomal Proteins; Proteins, Non-Histone Chromosomal; Nonhistone Chromosomal Proteins; Non Histone Chromosomal Proteins; Non Histone Chromosomal Phosphoproteins; Chromosomal Phosphoproteins, Non-Histone; Non-Histone Chromosomal Phosphoproteins; Chromosomal Proteins, Nonhistone; Chromosomal Proteins, Non Histone
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
toutatis protein, Drosophila  0   *Chromosomal Proteins, Non-Histone *Drosophila Proteins Zinc Fingers. Genet Res. 2001 Oct;78(2):137-48.
Smarce1 protein, rat  0   *Chromosomal Proteins, Non-Histone. J Biol Chem. 2012 Feb 24;287(9):6387-405.
Brdt protein, rat  0   *Chromosomal Proteins, Non-Histone. J Biol Chem. 2012 Feb 24;287(9):6387-405.
Wdr82 protein, mouse  0   *Chromosomal Proteins, Non-Histone Protein Subunits. Biol Reprod. 2011 Apr;84(4):756-64.
CENP-N protein, human  0   *Chromosomal Proteins, Non-Histone. Nat Cell Biol. 2006 May;8(5):458-69.
VIP4 protein, Arabidopsis  0   *Chromosomal Proteins, Non-Histone *Arabidopsis Proteins. Plant J. 2002 Sep;31(5):663-73.
Cbx4 protein, rat  EC 6.3.2.-   *Chromosomal Proteins, Non-Histone.
Cbx4 protein, mouse  EC 6.3.2.-   *Chromosomal Proteins, Non-Histone.
Cbx2 protein, rat  0   *Chromosomal Proteins, Non-Histone.
CBX2 protein, human  0   *Chromosomal Proteins, Non-Histone.
methylosome protein 50, Xenopus  0   *Chromosomal Proteins, Non-Histone *Xenopus Proteins. J Biol Chem. 2011 Dec 9;286(49):42221-31.
SMC-3 protein, C elegans  EC 3.6.1.3   *Chromosomal Proteins, Non-Histone *Caenorhabditis elegans Proteins Adenosine Triphosphatases Protein Subunits. PLoS One. 2011;6(9):e24799.
STRUCTURE SPECIFIC RECOGNITION PROTEIN 1, Arabidopsis  0   *Chromosomal Proteins, Non-Histone *Arabidopsis Proteins High Mobility Group Proteins. Plant J 2004 Dec;40(5):660-71
XLR6 protein, mouse  0   *Chromosomal Proteins, Non-Histone Nuclear Proteins. Biol Reprod 2011 Jul;85(1):165-71
no child left behind protein, Drosophila  0   *Chromosomal Proteins, Non-Histone *Drosophila Proteins. Development 2011 Aug;138(16):3357-66
RBL protein, Arabidopsis  0   *Chromosomal Proteins, Non-Histone *Arabidopsis Proteins. PLoS Genet 2011 Mar;7(3):e1001330
ASH2R protein, Arabidopsis  0   *Chromosomal Proteins, Non-Histone *Arabidopsis Proteins. PLoS Genet 2011 Mar;7(3):e1001330
Ctf4 protein, Drosophila  0   *Cell Cycle Proteins *Drosophila Proteins Chromosomal Proteins, Non-Histone. BMC Mol Biol 2011;12:13
CAP-H protein, human  0   *Chromosomal Proteins, Non-Histone. Nature. 2011 Jun 23;474(7352):477-83
CENP-Q protein, human  0   *Chromosomal Proteins, Non-Histone Centromere. J Biol Chem 2011 Jun 3;286(22):19744-57
LIN-61 protein, C elegans  0   *Chromosomal Proteins, Non-Histone *Caenorhabditis elegans Proteins. PLoS Genet 2011 Mar;7(3):e1002017
Fft3 protein, S pombe  0   *Chromosomal Proteins, Non-Histone *Schizosaccharomyces pombe Proteins. PLoS Genet 2011 Mar;7(3):e1001334
BAHD1 protein, mouse  0   *Chromosomal Proteins, Non-Histone. Science 2011 Mar 11;331(6022):1319-21
GINS2 protein, human  0   *Chromosomal Proteins, Non-Histone. Neoplasia 2010 Nov;12(11):877-88
RAD21L protein, mouse  0   *Chromosomal Proteins, Non-Histone *Cell Cycle Proteins Protein Subunits. J Cell Biol 2011 Jan 24;192(2):263-76
MCM-BP protein, Xenopus  0   *Chromosomal Proteins, Non-Histone *Xenopus Proteins. Genes Dev 2011 Jan 15;25(2):165-75
chromosome alignment-maintaining phosphoprotein, human  0   *Chromosomal Proteins, Non-Histone *Phosphoproteins Zinc Fingers. EMBO J 2011 Jan 5;30(1):130-44
MCM2 protein, Drosophila  0   *Chromosomal Proteins, Non-Histone *Drosophila Proteins. Genetics 2010 Aug;185(4):1151-65
Cbh1 protein, S pombe  0   *Chromosomal Proteins, Non-Histone *Schizosaccharomyces pombe Proteins. Nature. 2011 Jan 6;469(7328):112-5
MRG15 protein, Drosophila  0   *Chromosomal Proteins, Non-Histone *Drosophila Proteins. Exp Gerontol 2010 Nov;45(11):825-33
dalmatian protein, Drosophila  0   *Chromosomal Proteins, Non-Histone *Drosophila Proteins. Cell 2010 Nov 24;143(5):737-49
Wapl protein, Drosophila  0   *Chromosomal Proteins, Non-Histone *Drosophila Proteins. Cell 2010 Nov 24;143(5):737-49
mitoshell protein, Drosophila  0   *Chromosomal Proteins, Non-Histone *Drosophila Proteins. DNA Cell Biol 2010 Sep;29(9):487-98
SMC4 protein, mouse  0   *Chromosomal Proteins, Non-Histone. Nucleic Acids Res. 2010 Jun;38(10):3454-65
SMC2 protein, mouse  0   *Chromosomal Proteins, Non-Histone. Nucleic Acids Res. 2010 Jun;38(10):3454-65
EXPAND1 protein, human  0   *Chromosomal Proteins, Non-Histone. Mol Cell 2010 Mar 26;37(6):854-64
solo protein, Drosophila  0   *Chromosomal Proteins, Non-Histone *Drosophila Proteins. J Cell Biol 2010 Feb 8;188(3):335-49
MCPH1 protein, mouse  0   *Chromosomal Proteins, Non-Histone. PLoS Genet 2010;6(1):e1000826
Asf1a protein, mouse  0   *Chromosomal Proteins, Non-Histone. BMC Mol Biol 2009;10:110
MBTD1 protein, human  0   *Chromosomal Proteins, Non-Histone. PLoS One 2009;4(10):e7274
SYP-3 protein, C elegans  0   *Chromosomal Proteins, Non-Histone *Caenorhabditis elegans Proteins. PLoS Genet 2009 Oct;5(10):e1000668
RRP1B protein, mouse  0   *Chromosomal Proteins, Non-Histone. J Biol Chem 2009 Oct 16;284(42):28660-73
BAHD1 protein, human  0   *Chromosomal Proteins, Non-Histone. Proc Natl Acad Sci U S A 2009 Aug 18;106(33):13826-31
SMC3 protein, Drosophila  EC 3.6.1.3   *Adenosine Triphosphatases *Drosophila Proteins Chromosomal Proteins, Non-Histone. Chromosome Res 2009;17(2):185-200
SCC3 protein, Xenopus  0   *Chromosomal Proteins, Non-Histone *Xenopus Proteins. J Cell Biol 2000 Aug 7;150(3):405-16
SMC3 protein, Xenopus  0   *Chromosomal Proteins, Non-Histone *Xenopus Proteins. Chromosome Res 2009;17(2):165-84
psm3 protein, S pombe  0   *Chromosomal Proteins, Non-Histone *Schizosaccharomyces pombe Proteins.
psm1 protein, S pombe  0   *Chromosomal Proteins, Non-Histone *Schizosaccharomyces pombe Proteins.
psc3 protein, S pombe  0   *Chromosomal Proteins, Non-Histone *Schizosaccharomyces pombe Proteins.
CENP-O protein, human  0   *Chromosomal Proteins, Non-Histone. J Rheumatol 2009 Apr;36(4):781-6
Hip protein, Drosophila  0   *Chromosomal Proteins, Non-Histone *Drosophila Proteins. Chromosome Res 2009;17(1):19-36
umbrea protein, Drosophila  0   *Chromosomal Proteins, Non-Histone *Drosophila Proteins DNA-Binding Proteins. Chromosome Res 2009;17(1):19-36
Cep63 protein, Xenopus  0   *Chromosomal Proteins, Non-Histone *Xenopus Proteins. Nat Cell Biol 2009 Mar;11(3):278-85
modigliani protein, Drosophila  0   *Chromosomal Proteins, Non-Histone *Drosophila Proteins. Proc Natl Acad Sci U S A 2009 Feb 17;106(7):2271-6
ZFP541 protein, mouse  0   *Carrier Proteins *Chromosomal Proteins, Non-Histone Zinc Fingers. J Biol Chem 2008 Dec 12;283(50):35283-94
STN1 protein, Arabidopsis  0   *Chromosomal Proteins, Non-Histone *Arabidopsis Proteins. Proc Natl Acad Sci U S A 2008 Dec 16;105(50):19815-20
WDR82 protein, human  0   *Chromosomal Proteins, Non-Histone. Mol Cell Biol 2008 Jan;28(2):609-18
CENP-T protein, human  0   *Chromosomal Proteins, Non-Histone. Cell 2008 Dec 12;135(6):1039-52
CENP-W protein, human  0   *Chromosomal Proteins, Non-Histone. Cell 2008 Dec 12;135(6):1039-52
Chp2 protein, S cerevisiae  0   *Chromosomal Proteins, Non-Histone *Saccharomyces cerevisiae Proteins. Mol Cell Biol 2008 Dec;28(23):6973-88
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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