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Clofazimine

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Definition: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)     
Pharmacological Action Anti-Inflammatory Agents, Non-Steroidal; Coloring Agents; Leprostatic Agents
Other names G30,320; G 30,320; B663; B 663; N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-((1-methylet; Lamprene; G-30,320; B-663Drugs* : LAMPRENE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
B 4121  0   Clofazimine/*analogs & derivatives Drug Resistance, Multiple. Oncol Rep 2000 Jan-Feb;7(1):193-5
B 4157  0   Clofazimine/*analogs & derivatives. Antimicrob Agents Chemother 1996 Mar;40(3):633-6
B 4154  0   Clofazimine/*analogs & derivatives. Antimicrob Agents Chemother 1996 Mar;40(3):633-6
B 746  103051-26-9   Clofazimine/*analogs & derivatives. Tuber Lung Dis 1992 Aug;73(4):192-9
3-(beta-D-glucopyranosiduronic acid)-10-(4-chlorophenyl)-2,10-dihydro-2-isopropyliminophenazine  80832-47-9 beta-D-Glucopyranosiduronic acid, 5-(4-chlorophenyl)-3,5-dihydro-3-((1-methylethyl)imino)-2-phenazinyl  Clofazimine/*analogs & derivatives. Drug Metab Dispos 1981;9(6):521
3-(4-hydroxyanilino)-10-(4-chlorophenyl)-2,10-dihydro-2-isopropyliminophenazine  80832-46-8 Phenol, 4-((5-(4-chlorophenyl)-3,5-dihydro-3-((1-methylethyl)imino)-2-phenazinyl)amino)  Clofazimine/*analogs & derivatives. Drug Metab Dispos 1981;9(6):521
B 1056  78182-95-3 1,2-Ethanediamine, N,N-diethyl-N'-(10-phenyl-3-(phenylamino)-2(10H)-phenazinylidene)-, monohydrochloride  Clofazimine/*analogs & derivatives. Lepr Rev 1981;52(1):23
B 669  78182-92-0 2-Phenazinamine, 3-(cyclohexylimino)-3,5-dihydro-N,5-diphenyl  Clofazimine/*analogs & derivatives. Lepr Rev 1981;52(1):23
B 775  78182-94-2   Clofazimine/*analogs & derivatives. Lepr Rev 1981;52(1):23
B 749  78182-93-1 1,2-Ethanediamine, N'-(10-(4-chlorophenyl)-3-((4-chlorophenyl)amino)-2(10H)-phenazinylidene)-N,N-diethyl  Clofazimine/*analogs & derivatives. Lepr Rev 1981;52(1):23
B1912  24028-59-9 8-chloro-3-(cyclohexylmino)-3,5-dihydro-N,5-diphenyl-2-phenazinamine  Clofazimine/*analogs & derivatives. Chemotherapy 22(3-4):242;1976; Int J Lepr 5(2):188;1977; Lepr India 48(4 suppl)686;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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