encyclopedia of medical concepts
ψ 

Cotinine

More information in Books or onNLM PubMed
Definition: The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It has CNS stimulating properties.     
Pharmacological Action Indicators and Reagents 		Other names Scotine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5'-hydroxycotinine-N-oxide  0   Cotinine/*analogs & derivatives Nicotine/metabolism. Xenobiotica 1999 Aug;29(8):793-801
N-hydroxymethylnorcotinine  0   Cotinine/*analogs & derivatives. Xenobiotica 1994 May;24(5):409-15
cotinine N-glucuronide  0   Cotinine/*analogs & derivatives. Chem Res Toxicol 1992 Mar-Apr;5(2):280-5
norcotinine  17114-40-8   Cotinine/*analogs & derivatives. Toxicol Appl Pharmacol 1990;105(3):382
N-(4-hydroxyphenethyl)cotinine carboxamide  100333-39-9 3-Pyrrolidinecarboxamide, N-(2-(4-hydroxyphenyl)ethyl)-1-methyl-5-oxo-2-(3-pyridinyl)-, (2S-trans)  Cotinine/*analogs & derivatives. Clin Chem 1985;31(1):118
cotinine-N-oxide  36508-80-2   Cotinine/*analogs & derivatives. J Med Chem 15(8):840;1972
hydroxycotinine  27323-64-4 3-hydroxy-1-methyl-5-(3-pyridinyl)-2- pyrrolidinone  Cotinine/*analogs & derivatives. J Med Chem 15(4):356;1972

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy