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Creatine Kinase

More information in Books or onNLM PubMed
Definition: A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.     
Examples Creatine Kinase, BB Form; Creatine Kinase, MB Form; Creatine Kinase, Mitochondrial Form; Creatine Kinase, MM Form 		Other names Creatine Phosphokinase; Phosphotransferase, ATP Creatine; Phosphotransferase, ADP Phosphocreatine; Phosphokinase, Creatine; Phosphocreatine Phosphotransferase, ADP; Macro Creatine Kinase; Kinase, Creatine; Creatine Phosphotransferase, ATP; Macro-Creatine Kinase; ATP Creatine Phosphotransferase; ADP Phosphocreatine Phosphotransferase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
CKMT2 protein, human  EC 2.7.3.2   *Creatine Kinase.
CKMT1A protein, human  EC 2.7.3.2   *Creatine Kinase. J Med Genet 2007 Apr;44(4):233-40
N-dibenzylphospho-N'-3-(2,6-dichlorophenyl)propylguanidine  0   *Guanidines Creatine Kinase/antagonists & inhibitors. Biochim Biophys Acta 1997 Sep 26;1342(1):83-9
KC 764  94457-09-7   *Bicyclo Compounds *Nicotinic Acids Aspartate Aminotransferases/antagonists & inhibitors Creatine Kinase/antagonists & inhibitors L-Lactate Dehydrogenase/antagonists & inhibitors. Arzneimittelforschung 1992 Jan;42(1):32-9
estrogen-induced uterine creatine kinase, rat  0   *Creatine Kinase *Muscle Proteins Estrogens Uterus. Endocrinology 1979;105(5):1248; J Endocrinol 63(3):439;1974; Life Sci 1980;27(12):111; Life Sci 22:217;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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