Cryptorchidism (definition)

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Cryptorchidism

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Definition: A developmental defect in which a TESTIS or both TESTES failed to descend from high in the ABDOMEN to the bottom of the SCROTUM. Testicular descent is essential to normal SPERMATOGENESIS which requires temperature lower than the BODY TEMPERATURE. Cryptorchidism can be subclassified by the location of the maldescended testis.

Other names Testis, Undescended; Undescended Testis; Undescended Testes; Cryptorchidism, Unilateral; Cryptorchidism, Inguinal; Cryptorchidism, Bilateral; Cryptorchidism, Abdominal; Unilateral Cryptorchidism; Testes, Undescended; Inguinal Cryptorchidism; Cryptorchism; Bilateral Cryptorchidism; Abdominal Cryptorchidism

Substance	Categories	Source
McDonough syndrome	Abnormalities, Multiple Cryptorchidism Heart Defects, Congenital Kyphosis Intellectual Disability Facies Rectus Abdominis/abnormalities.
Lynch Lee Murday syndrome	Spine Cryptorchidism Deafness Intellectual Disability Limb Deformities, Congenital.
Growth mental deficiency syndrome of Myhre	Facies Cryptorchidism Growth Disorders Hand Deformities, Congenital Hypertrophy Joint Diseases *Intellectual Disability.	J Med Genet. 2003; 40(7):546-51
Arroyo Garcia Cimadevilla syndrome	Anophthalmos Cryptorchidism *Esophageal Atresia.
Ichthyosis and male hypogonadism	Cryptorchidism Hypogonadism Intellectual Disability Ichthyosis, X-Linked.
Singh Chhaparwal Dhanda syndrome	Cataract Cryptorchidism Dwarfism Intellectual Disability Nystagmus, Pathologic Strabismus Patella/abnormalities.
Torticollis keloids cryptorchidism renal dysplasia	Cryptorchidism Keloid *Torticollis Kidney/abnormalities.
Arthrogryposis multiplex congenita pulmonary hypoplasia	Abnormalities, Multiple Arthrogryposis Cryptorchidism Eye Abnormalities *Craniofacial Abnormalities.
Urioste Martinez-Frias syndrome	Abnormalities, Multiple Cryptorchidism Polydactyly Craniofacial Abnormalities *46, XY Disorders of Sex Development Mullerian Ducts/abnormalities.
Carnevale syndrome	Blepharoptosis Cryptorchidism Hip Dislocation, Congenital Strabismus Abdominal Muscles/abnormalities.
RXFP2 protein, human	*Receptors, G-Protein-Coupled Cryptorchidism.	Hum Mol Genet 2002 Sep 15;11(19):2309-18

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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