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Cryptorchidism

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Definition: A developmental defect in which a TESTIS or both TESTES failed to descend from high in the ABDOMEN to the bottom of the SCROTUM. Testicular descent is essential to normal SPERMATOGENESIS which requires temperature lower than the BODY TEMPERATURE. Cryptorchidism can be subclassified by the location of the maldescended testis.      Other names Testis, Undescended; Undescended Testis; Undescended Testes; Cryptorchidism, Unilateral; Cryptorchidism, Inguinal; Cryptorchidism, Bilateral; Cryptorchidism, Abdominal; Unilateral Cryptorchidism; Testes, Undescended; Inguinal Cryptorchidism; Cryptorchism; Bilateral Cryptorchidism; Abdominal Cryptorchidism
 
SubstanceCAS Registry & nameCategoriesSource
McDonough syndrome  0   *Abnormalities, Multiple *Cryptorchidism *Heart Defects, Congenital *Kyphosis *Intellectual Disability *Facies Rectus Abdominis/abnormalities.
Lynch Lee Murday syndrome  0   Spine *Cryptorchidism *Deafness *Intellectual Disability *Limb Deformities, Congenital.
Growth mental deficiency syndrome of Myhre  0   *Facies *Cryptorchidism *Growth Disorders *Hand Deformities, Congenital *Hypertrophy *Joint Diseases *Intellectual Disability. J Med Genet. 2003; 40(7):546-51
Arroyo Garcia Cimadevilla syndrome  0   *Anophthalmos *Cryptorchidism *Esophageal Atresia.
Ichthyosis and male hypogonadism  0   *Cryptorchidism *Hypogonadism *Intellectual Disability *Ichthyosis, X-Linked.
Singh Chhaparwal Dhanda syndrome  0   *Cataract *Cryptorchidism *Dwarfism *Intellectual Disability *Nystagmus, Pathologic *Strabismus Patella/abnormalities.
Torticollis keloids cryptorchidism renal dysplasia  0   *Cryptorchidism *Keloid *Torticollis Kidney/abnormalities.
Arthrogryposis multiplex congenita pulmonary hypoplasia  0   *Abnormalities, Multiple *Arthrogryposis *Cryptorchidism *Eye Abnormalities *Craniofacial Abnormalities.
Urioste Martinez-Frias syndrome  0   *Abnormalities, Multiple *Cryptorchidism *Polydactyly *Craniofacial Abnormalities *46, XY Disorders of Sex Development Mullerian Ducts/abnormalities.
Carnevale syndrome  0   *Blepharoptosis *Cryptorchidism *Hip Dislocation, Congenital *Strabismus Abdominal Muscles/abnormalities.
RXFP2 protein, human  0   *Receptors, G-Protein-Coupled Cryptorchidism. Hum Mol Genet 2002 Sep 15;11(19):2309-18

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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