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Receptors, G-Protein-Coupled
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Definition
: The largest family of cell surface receptors involved in SIGNAL TRANSDUCTION. They share a common structure and signal through HETEROTRIMERIC G-PROTEINS.
GEN or unspecified; prefer specifics
Examples
Calcitonin Receptor-Like Protein
;
Frizzled Receptors
;
Receptor, Anaphylatoxin C5a
;
Receptor, PAR-2
;
Receptors, Adrenomedullin
;
Receptors, Angiotensin
;
Receptors, Bombesin
;
Receptors, Bradykinin
;
Receptors, Calcitonin
;
Receptors, Calcitonin Gene-Related Peptide
;
Receptors, Calcium-Sensing
;
Receptors, Cannabinoid
;
Receptors, Catecholamine
;
Receptors, Chemokine
;
Receptors, Cholecystokinin
;
Receptors, Corticotropin-Releasing Hormone
;
Receptors, Eicosanoid
;
Receptors, Endothelin
;
Receptors, Formyl Peptide
;
Receptors, FSH
;
Receptors, GABA-B
;
Receptors, Galanin
;
Receptors, Ghrelin
;
Receptors, Glucagon
;
Receptors, Histamine H1
;
Receptors, Histamine H2
;
Receptors, Islet Amyloid Polypeptide
;
Receptors, LH
;
Receptors, LHRH
;
Receptors, Lysophospholipid
;
Receptors, Melanocortin
;
Receptors, Melatonin
;
Receptors, Metabotropic Glutamate
;
Receptors, Muscarinic
;
Receptors, Neuropeptide Y
;
Receptors, Neurotensin
;
Receptors, Odorant
;
Receptors, Opioid
;
Receptors, Oxytocin
;
Receptors, Parathyroid Hormone
;
Receptors, Pheromone
;
Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide
;
Receptors, Purinergic
;
Receptors, Serotonin
;
Receptors, Somatostatin
;
Receptors, Thrombin
;
Receptors, Vasoactive Intestinal Peptide
;
Receptors, Vasopressin
;
Rhodopsin
Other names
Receptors, G Protein Coupled; G Protein Coupled Receptors; G-
Protein-
Coupled Receptors
Substance
CAS Registry & name
Categories
Source
Drugs
*
GPR18 protein, mouse
0
*Receptors, G-Protein-Coupled.
Mamm Genome. 1996 Dec;7(12):920-1.
CG4395 protein, Drosophila
0
*Drosophila Proteins
*Receptors, G-Protein-Coupled.
PLoS One. 2011;6(11):e28369.
GPR21 protein, mouse
0
*Receptors, G-Protein-Coupled.
Biochem Biophys Res Commun. 2012 Feb 3;418(1):1-5.
Cand7 protein, Arabidopsis
0
*Arabidopsis Proteins
*Receptors, G-Protein-Coupled.
Biochem Biophys Res Commun. 2012 Jan 20;417(3):991-5.
Cand2 protein, Arabidopsis
0
*Arabidopsis Proteins
*Receptors, G-Protein-Coupled.
Biochem Biophys Res Commun. 2012 Jan 20;417(3):991-5.
MrgF protein, mouse
0
*Receptors, G-Protein-Coupled.
Mol Pain. 2008 Jan 15;4:2.
GPR133 protein, mouse
0
*Cell Adhesion Molecules
*Receptors, G-Protein-Coupled.
J Biol Chem. 2011 Dec 9;286(49):41912-6.
Gpr153 protein, human
0
*Receptors, G-Protein-Coupled.
Biochim Biophys Acta. 2005 Apr 15;1722(3):235-46.
Gpr162 protein, human
0
*Receptors, G-Protein-Coupled.
Biochim Biophys Acta. 2005 Apr 15;1722(3):235-46.
dihydrocaffeic acid receptor 1, C elegans
0
*Caenorhabditis elegans Proteins
*Receptors, G-Protein-Coupled.
J Neurosci. 2011 Nov 16;31(46):16603-10
STR-
33 protein, C elegans
0
*Caenorhabditis elegans Proteins
*Receptors, G-Protein-Coupled.
J Biol Chem. 2011 Nov 18;286(46):39860-70
Lgr6 protein, zebrafish
0
*Zebrafish Proteins
*Receptors, G-Protein-Coupled.
Gene Expr Patterns. 2011 Oct;11(7):378-83.
Lgr4 protein, zebrafish
0
*Receptors, G-Protein-Coupled.
Gene Expr Patterns. 2011 Oct;11(7):378-83.
GPR55 protein, rat
0
*Receptors, G-Protein-Coupled
*Receptors, Cannabinoid.
Br J Pharmacol. 2007 Dec;152(7):1092-101.
GPR172B protein, human
0
*Membrane Transport Proteins
*Receptors, G-Protein-Coupled.
Hum Mutat. 2011 Jan;32(1):E1976-84.
TAS2R1 protein, human
0
*Receptors, G-Protein-Coupled
Taste.
J Recept Signal Transduct Res. 2011 Jun;31(3):229-40.
GPR61 protein, mouse
0
*Receptors, G-Protein-Coupled.
Life Sci. 2011 Nov 21;89(21-22):765-72
CG34381 protein, Drosophila
0
*Drosophila Proteins
*Receptors, G-Protein-Coupled.
Biochem Biophys Res Commun. 2011 Oct 14;414(1):44-8.
RXFP4 protein, mouse
0
*Receptors, G-Protein-Coupled.
Biochemistry. 2011 Oct 4;50(39):8352-61.
GPRC5C protein, mouse
0
*Receptors, G-Protein-Coupled.
Biochem Biophys Res Commun 2011 Sep 2;412(3):460-5
Tas2R108 protein, mouse
0
*Receptors, G-Protein-Coupled.
Proc Natl Acad Sci U S A 2011 Jun 7;108(23):9478-83
Tas2R105 protein, mouse
0
*Receptors, G-Protein-Coupled.
Proc Natl Acad Sci U S A 2011 Jun 7;108(23):9478-83
Rxfp1 protein, zebrafish
0
*Zebrafish Proteins
*Receptors, G-Protein-Coupled
Receptors, Peptide.
Dev Growth Differ 2010 Dec;52(9):799-806
OCTR-
1 protein, C elegans
0
*Caenorhabditis elegans Proteins
*Receptors, G-Protein-Coupled.
Science. 2011 May 6;332(6030):729-32
GPR91 protein, human
0
*Receptors, G-Protein-Coupled.
J Mol Biol 2001 Mar 30;307(3):799-813
RXFP2 protein, mouse
0
*Receptors, G-Protein-Coupled.
Mamm Genome. 2010 Oct;21(9-10):442-9
CG30106 protein, Drosophila
0
*Drosophila Proteins
*Receptors, G-Protein-Coupled.
Biochem Biophys Res Commun 2011 Jan 7;404(1):184-9
CG14593 protein, Drosophila
0
*Drosophila Proteins
*Receptors, G-Protein-Coupled.
Biochem Biophys Res Commun 2011 Jan 7;404(1):184-9
GPR160 protein, human
0
*Receptors, G-Protein-Coupled.
Cell Prolif 2011 Feb;44(1):59-66
GPR177 protein, zebrafish
0
*Zebrafish Proteins
*Receptors, G-Protein-Coupled.
Dev Dyn 2010 Sep;239(9):2426-34
Hcar2 protein, rat
0
*Receptors, Nicotinic
*Receptors, G-Protein-Coupled.
Bioorg Med Chem Lett 2010 Sep 15;20(18):5426-30
GPRC5A protein, mouse
0
*Receptors, G-Protein-Coupled.
Cancer Res. 2010 Nov 1;70(21):8917-26
GPR124 protein, mouse
0
*Receptors, G-Protein-Coupled.
Science 2010 Nov 12;330(6006):985-9
Gpr183 protein, rat
0
*Receptors, G-Protein-Coupled.
Nature. 2010 Sep 23;467(7314):460-4
Gpr155 protein, mouse
0
*Receptors, G-Protein-Coupled.
Biochem Biophys Res Commun 2010 Jul 16;398(1):19-25
Gpr126 protein, mouse
0
*Receptors, G-Protein-Coupled.
PLoS One 2010;5(2):e9198
GPER protein, zebrafish
0
*Zebrafish Proteins
*Receptors, G-Protein-Coupled.
Dev Biol 2010 Jun 15;342(2):194-206
GPR177 protein, rat
0
*Receptors, G-Protein-Coupled
*Intracellular Signaling Peptides and Proteins.
BMC Neurosci. 2010;11() (dup#18):33
GPR177 protein, human
0
*Receptors, G-Protein-Coupled
*Intracellular Signaling Peptides and Proteins.
BMC Neurosci. 2010;11() (dup#18):33
GPR125 protein, human
0
*Receptors, G-Protein-Coupled.
Biol Reprod 2010 Feb;82(2):363-72
Lgr6 protein, mouse
0
*Receptors, G-Protein-Coupled.
Science. 2010 Mar 12;327(5971):1385-9
Gpr149 protein, mouse
0
*Receptors, G-Protein-Coupled.
Endocrinology 2010 Jan;151(1):358-68
GPR133 protein, human
0
*Receptors, G-Protein-Coupled.
Hum Mol Genet 2009 Dec 1;18(23):4662-8
MrgprA3 protein, mouse
0
*Receptors, G-Protein-Coupled.
Cell. 2009 Dec 24;139(7):1353-65
SRBC-
66 protein, C elegans
0
*Caenorhabditis elegans Proteins
*Receptors, G-Protein-Coupled.
Science. 2009 Nov 13;326(5955):994-8
SRBC-
64 protein, C elegans
0
*Caenorhabditis elegans Proteins
*Receptors, G-Protein-Coupled.
Science. 2009 Nov 13;326(5955):994-8
Gpr177 protein, mouse
0
*Receptors, G-Protein-Coupled
*Intracellular Signaling Peptides and Proteins.
Proc Natl Acad Sci U S A 2009 Nov 3;106(44):18598-603
Gpr183 protein, mouse
0
*Receptors, G-Protein-Coupled.
Immunity 2009 Aug 21;31(2):259-69
gpr126 protein, Zebrafish
0
*Zebrafish Proteins
*Receptors, G-Protein-Coupled.
Science. 2009 Sep 11;325(5946):1353-4
TDAG8 protein, rat
0
*Receptors, G-Protein-Coupled.
Biochem Biophys Res Commun 2009 Aug 28;386(3):420-5
moody protein, Drosophila
0
*Drosophila Proteins
*Receptors, G-Protein-Coupled.
Cell 2005 Oct 7;123(1):145-56
sensory neuron-
specific receptor 1, rat
0
*Receptors, G-Protein-Coupled.
Pain. 2009 May;143(1-2):130-7
GPR30 protein, zebrafish
0
*Receptors, Estradiol
*Receptors, G-Protein-Coupled.
Gen Comp Endocrinol 2009 Mar;161(1):58-61
GPR172A protein, human
0
*Receptors, G-Protein-Coupled.
Proc Natl Acad Sci U S A 2009 Apr 7;106(14):5848-53
ceramide 1-
phosphate receptor, mouse
0
*Receptors, G-Protein-Coupled.
Cell Signal 2009 Mar;21(3):405-12
GPR63 protein, human
0
*Receptors, G-Protein-Coupled.
Clin Genet 2009 Feb;75(2):199-202
pyrokinin receptor, C elegans
0
*Caenorhabditis elegans Proteins
*Receptors, G-Protein-Coupled.
Biochem Biophys Res Commun 2009 Feb 13;379(3):760-4
GPR39 protein, rat
0
*Receptors, G-Protein-Coupled.
Peptides 2008 Dec;29(12):2150-8
GPR17 protein, mouse
0
*Nerve Tissue Proteins
*Receptors, G-Protein-Coupled.
EMBO J 2006 Oct 4;25(19):4615-27
GTG2 protein, Arabidopsis
EC 3.6.1.-
*Arabidopsis Proteins
*Receptors, G-Protein-Coupled
GTP-Binding Proteins.
Cell 2009 Jan 9;136(1):136-48
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