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Receptors, GABA-B

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Definition: A subset of GABA RECEPTORS that signal through their interaction with HETEROTRIMERIC G-PROTEINS.      Other names GABA-B Receptors; Baclofen Receptors; Receptors, GABA B; Receptor, GABA-B; Receptor, Baclofen; GABA B Receptors; GABA B Receptor; Receptors, Baclofen; GABA-B Receptor; Baclofen Receptor
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-(bicyclo(2.2.1)hept-2-yl)-2-methyl-5-(4-(trifluoromethyl)phenyl)-4-pyrimidinamine  0   *Norbornanes *Pyrimidines Receptors, GABA-B GABA Modulators. Psychopharmacology (Berl) 2011 May;215(1):117-28
3-amino-2-hydroxypropylcyclohexylmethylphosphinic acid  0   *Phosphinic Acids Receptors, GABA-B/antagonists & inhibitors. Br J Pharmacol 2006 Nov;149(5):581-90
Gabbr2 protein, mouse  0   *Receptors, GABA-B.
GABBR2 protein, human  0   *Receptors, GABA-B.
CGP 13501  0   *Phenols Receptors, GABA-B/agonists. Mol Pharmacol 2001 Nov;60(5):963-71
CGP 7930  0   *Phenols Receptors, GABA-B/agonists. Mol Pharmacol 2001 Nov;60(5):963-71
5-amino-3-(4-chlophenyl)pentanoic acid  0   Baclofen/*analogs & derivatives Receptors, GABA-B. Eur J Pharmacol 2001 Apr 13;417(3):177-80
CGP 47332A  0   *Phosphinic Acids Receptors, GABA-B/antagonists & inhibitors. Eur J Pharmacol 1999 Oct 27;383(2):137-41
3-aminopropyl-(1,1,-difluoro-n-butyl)phosphinic acid  0   *Phosphinic Acids Receptors, GABA-B/antagonists & inhibitors. Eur J Pharmacol 1999 Jun 25;374(3):351-4
3-aminopropyl-P-(alpha-hydroxybenzyl)phosphinic acid  0   *Phosphinic Acids Receptors, GABA-B/antagonists & inhibitors. Eur J Pharmacol 1999 Jun 25;374(3):351-4
Gabbr2 protein, rat  0   *Receptors, GABA-B. Genomics 1999 Mar 15;56(3):288-95; Nature 1998 Dec 17;396(6712):674-9; Science 1999 Jan 1;283(5398):74-7
4-hydroxy-4-(4'-chlorophenyl)hexanamide  0   *Amides Receptors, GABA-B/antagonists & inhibitors. Arzneimittelforschung 1998 Aug;48(8):797-801
3-hydroxy-3-(4'-chlorophenyl)pentanamide  0   *Amides Receptors, GABA-B/antagonists & inhibitors. Arzneimittelforschung 1998 Aug;48(8):797-801
2-hydroxy-2-(4'-chlorophenyl)butyramide  0   *Amides Receptors, GABA-B/antagonists & inhibitors. Arzneimittelforschung 1998 Aug;48(8):797-801
CGP 44532  0   *Phosphinic Acids gamma-Aminobutyric Acid/*analogs & derivatives Receptors, GABA-B/agonists. Life Sci 1998;62(17-18):1525-30
CGP 61334  0   *Phosphinic Acids *Benzoic Acids Receptors, GABA-B/antagonists & inhibitors. Eur J Pharmacol 1997 Feb 5;320(1):9-13
(3-(1-((3-(cyclohexylmethyl)hydroxyphosphinyl)-2-hydroxypropyl)amino)ethyl)benzoic acid  153994-81-1   *Phosphinic Acids *Benzoic Acids Receptors, GABA-B/antagonists & inhibitors. Eur J Pharmacol 1997 Feb 5;320(1):9-13
GABA type B receptor, subunit 1  0   *Receptors, GABA-B. Nature 1997 Mar 20;386(6622):239-46
CGP 71872  0   *Azides *Organophosphorus Compounds Iodine Radioisotopes Receptors, GABA-B/antagonists & inhibitors. Nature 1997 Mar 20;386(6622):239-46

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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