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Demecolcine
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Definition
: An alkaloid isolated from Colchicum autumnale L. and used as an antineoplastic.
/biosyn permitted if by plant
Pharmacological Action
Tubulin Modulators
;
Antineoplastic Agents, Phytogenic
Other names
Demecolcine, (+-
)-
Isomer; Colchamine; Colcemide; Colcemid
Substance
CAS Registry & name
Categories
Source
Drugs
*
NBD-
colcemid
108964-31-4
Demecolcine/*analogs & derivatives
4-Chloro-7-nitrobenzofurazan/*analogs & derivatives.
J Biol Chem 1987;262(13):6318
thiodemecolcine
76129-11-8
Demecolcine/*analogs & derivatives.
J Med Chem 1985;28(9):1204