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Erythritol

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Definition: A four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator.     
Pharmacological Action Vasodilator Agents
Examples Erythrityl Tetranitrate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
FCH(2)-methyl-D-erythritol 4-phosphate  0   Erythritol/*analogs & derivatives. Bioorg Med Chem Lett. 2008 May 15;18(10):3090-4
1,3,4,5-tetragalloylapiitol  0   Erythritol/*analogs & derivatives. J Nat Prod 2007 Oct;70(10):1647-9
2-C-trifluoromethylerythritol  0   Erythritol/*analogs & derivatives. J Org Chem. 2006 Apr 14;71(8):3278-81
1,4-anhydroerythritol  0   Erythritol/*analogs & derivatives. Anal Chem 2005 Jul 15;77(14):4503-8
phosphoric acid 3-fluoro-2,4-dihdyroxy-3-methylbutyl ester  0   *Sugar Phosphates Erythritol/*analogs & derivatives. Org Biomol Chem 2007 Jan 7;5(1):97-102
methyl-D-erythritol 2,4-cyclodiphosphate  0   Erythritol/*analogs & derivatives. Eur J Biochem 2001 Dec;268(23):6302-10
diacylmannosylerythritol  0   *Mannosides Erythritol/*analogs & derivatives. Biotechnol Prog 2001 Mar-Apr;17(2):362-5
1'-((1,4-dideoxy-1,4-iminoarabinitol)-4-N-ammonium)-1'-deoxyerythritol-3'-sulfate  0   *Quaternary Ammonium Compounds Arabinose Erythritol Imino Furanoses Glycoside Hydrolases/antagonists & inhibitors. J Am Chem Soc 2001 Jul 4;123(26):6268-71
bis(meso-oxolanediolato)borate  0   *Borates Erythritol/*analogs & derivatives. Carbohydr Res 2000 Jul 24;327(3):287-92
4-diphosphocytidyl-2C methylerythritol 2-phosphate  0   *Sugar Phosphates Erythritol/*analogs & derivatives. Proc Natl Acad Sci U S A 2000 Mar 14;97(6):2486-90
pentaerythritol dinitrate  1607-01-8   Erythritol/*analogs & derivatives. Arzneimittelforschung 1999 Nov;49(11):891-5
4-diphosphocytidyl-2-C-methylerythritol  0   Erythritol/*analogs & derivatives. Proc Natl Acad Sci U S A 1999 Oct 12;96(21):11758-63
2-C-methylerythritol 4-phosphate  0   *Sugar Phosphates Erythritol/*analogs & derivatives. Proc Natl Acad Sci U S A 1998 Aug 18;95(17):9879-84
2-C-methyl-1,3,4-triacetylerythritol  0   Erythritol/*analogs & derivatives. J Nat Prod 1996 Dec;59(12):1171-3
2,3-O-isopropylideneerythritol  0   Erythritol/*analogs & derivatives. Carbohydr Res 1994 Nov 15;264(2):237-51
erythritol 4-phosphate  7183-41-7 1,2,3,4-Butanetetrol, 1-(dihydrogen phosphate), (S-(R*,S*))  *Sugar Phosphates Erythritol/*analogs & derivatives. J Bacteriol 1993 Jul;175(13):3941-8
erythritol methacrylate  0   *Methacrylates Erythritol/*analogs & derivatives. Dent Mater J 1992 Jun;11(1):77-82
2-methyl-butan-1,2,3,4-tetraol-2,4-cyclopyrophosphate  141816-32-2   Erythritol/*analogs & derivatives Brevibacterium. FEBS Lett 1992 Feb 24;298(2-3):159-61
kelletinin I  87697-99-2 Benzoic acid, 4-hydroxy-, 1,2,3,4-butanetetrayl ester, (R*,S*)  *Hydroxybenzoic Acids Erythritol/*analogs & derivatives DNA Polymerase II/antagonists & inhibitors. Experientia 1991;47(1):64
3-C-methylerythritol  93921-83-6 1,2,3,4-Butanetetrol, 2-methyl-, (S-(R*,S*))  Erythritol/*analogs & derivatives. Carbohydr Res 1984;133(2):235
3-(hydroxymethyl)erythritol  10592-17-3   Erythritol/*analogs & derivatives. Carbohydr Res 1984;133(2):235
4-O-(3,4-O-(1-carboxyethylidene)-beta-galactopyranosyl)erithritol  87810-47-7 beta-D-Galactopyranoside, 2,3,4-trihydroxybutyl 3,4-O-(1-carboxyethylidene)-, (1(2R-(2R*,3S*)))  Erythritol/*analogs & derivatives Galactose/*analogs & derivatives. Carbohydr Res 1983;121:205
2,3-anhydroerythritol  57302-79-1   Erythritol/*analogs & derivatives. Carbohydrate Res 56:43;1977
ritrosulfan  4148-16-7 1,4-bis(2'-mesyloxyethylamino)-1,4-dideoxy-meso-erythritol  Erythritol/*analogs & derivatives. Acta Biol Acad Sci Hung 27(1):37;1976; Acta Pharm Hung 48(Suppl):49;1978; Mutation Res 57:241;1978; Neoplasma 18(3):277;1971; Ther Hung 1979;27(2):68

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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