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Etomidate
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Definition
: Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.
Pharmacological Action
Anesthetics, Intravenous
;
Hypnotics and Sedatives
Other names
R26490; R 26490; Radenarkon; R-
26490; Hypnomidate; Ethomidate
Drugs
*
:
AMIDATE
;
ETOMIDATE
Substance
CAS Registry & name
Categories
Source
Drugs
*
ethyl 1-
(1-
(4-
(3-
(trifluoromethyl)-
3H-
diazirin-
3-
yl)phenyl)ethyl)-
1H-
imidazole-
5-
carboxylate
0
Diazomethane/*analogs & derivatives
Etomidate/*analogs & derivatives.
J Med Chem 2010 Sep 9;53(17):6432-44
carboetomidate
0
*Pyrroles
Etomidate.
Anesthesiology. 2010 Mar;112(3):637-44
methoxycarbonyletomidate
0
Etomidate/*analogs & derivatives.
Anesthesiology 2009 Aug;111(2):240-9
iodophenyl metomidate
0
Etomidate/*analogs & derivatives
Iodine Radioisotopes.
J Med Chem 2008 Apr 10;51(7):2244-53
acyl azide etomidate
0
Etomidate/*analogs & derivatives.
J Biol Chem 2007 Apr 20;282(16):12038-47
4-
benzoylbenzyl 1-
(1-
phenylethyl)-
1H-
imidazole-
5-
carboxylate
0
*Benzophenones
Etomidate/*analogs & derivatives.
J Med Chem 2006 Aug 10;49(16):4818-25
4-
(3-
(trifluoromethyl)-
3H-
diazirin-
3-
yl)benzyl 1-
(1-
phenylethyl)-
1H-
imidazole-
5-
carboxylate
0
Diazomethane/*analogs & derivatives
Etomidate/*analogs & derivatives.
J Med Chem 2006 Aug 10;49(16):4818-25
azietomidate
0
Etomidate/*analogs & derivatives
Ligands.
J Med Chem 2003 Mar 27;46(7):1257-65
metomidate
5377-20-8 1H-
Imidazole-
5-
carboxylic acid, 1-
(1-
phenylethyl)-
, methyl ester
Etomidate/*analogs & derivatives
Carbon Radioisotopes
Radioactive Tracers.
R 8110
109872-40-4 1H-
Imidazole-
5-
carboxylic acid, 1-
(1-
(4-
fluorophenyl)ethyl)-
, ethyl ester, monohydrochloride
Etomidate/*analogs & derivatives.
Res Vet Sci 1987;42(2):200