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Heparin, Low-Molecular-Weight

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Definition: Heparin fractions with a molecular weight usually between 4000 and 6000 kD. These low-molecular-weight fractions are effective antithrombotic agents. Their administration reduces the risk of hemorrhage, they have a longer half-life, and their platelet interactions are reduced in comparison to unfractionated heparin. They also provide an effective prophylaxis against postoperative major pulmonary embolism.  /antag   
Pharmacological Action Anticoagulants; Fibrinolytic Agents
Examples Dalteparin; Enoxaparin; Nadroparin 		Other names Low-Molecular-Weight Heparin; LMWH; Heparin, Low Molecular Weight; Low Molecular Weight Heparin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
semuloparin  0   *Heparin, Low-Molecular-Weight Fibrinolytic Agents. Thromb Res. 2011 Oct;128(4):361-7
CDSO3 heparin  0   Heparin, Low-Molecular-Weight/*analogs & derivatives Antithrombins. Biochem Biophys Res Commun. 2011 Sep 23;413(2):348-52.
M-118 compound  0   *Heparin, Low-Molecular-Weight. Curr Opin Investig Drugs. 2010 Sep;11(9):1059-65
LMWH-DOCA conjugate  0   Deoxycholic Acid/*analogs & derivatives Heparin, Low-Molecular-Weight/*analogs & derivatives. J Control Release. 2006 Apr 10;111(3):290-8
NA-LMWH  0   Heparin, Low-Molecular-Weight/*analogs & derivatives. Thromb Haemost 2006 Dec;96(6):816-21
bemiparin  0   *Heparin, Low-Molecular-Weight. Thromb Haemost 2000 Apr;83(4):523-9
sulfhydryl low-molecular-weight heparin  0   *Heparin, Low-Molecular-Weight. FEBS Lett 2000 Feb 25;468(2-3):115-9
certoparin  0   *Heparin, Low-Molecular-Weight.
Pharma Action Anticoagulants 		Thromb Haemost 1999 Nov;82(5):1462-8
GM 1892  0   Heparin, Low-Molecular-Weight/*analogs & derivatives. J Surg Res 1995 Jul;59(1):211-8
reviparin  0   *Heparin, Low-Molecular-Weight.
Pharma Action Anticoagulants ; Fibrinolytic Agents 		Thromb Res 1994 Jan 15;73(2):85-93
ardeparin  0   *Heparin, Low-Molecular-Weight.
Pharma Action Anticoagulants ; Fibrinolytic Agents 		Thromb Res 1995 Jan 15;77(2):175-85NORMIFLO
Sandoparin  0   *Heparin, Low-Molecular-Weight. Semin Thromb Hemost 1993;19 Suppl 1:31-5
iodo-ardeparin  0   Heparin, Low-Molecular-Weight/*analogs & derivatives Iodine Radioisotopes. Drug Metab Dispos Biol Fate Chem 1994 Jan-Feb;22(1):175-6
ML 009723  0   *Heparin, Low-Molecular-Weight. Semin Thromb Hemost 1993;19 Suppl 1:58-62
tinzaparin  0   *Heparin, Low-Molecular-Weight.
Pharma Action Fibrinolytic Agents 		Haemostasis 1993 Mar;23 Suppl 1:10-14INNOHEP
parnaparin  0   *Heparin, Low-Molecular-Weight. Thromb Res 1992 May 1;66(2-3):141-50
CY 222  0   *Heparin, Low-Molecular-Weight.
Fluxum  0   *Heparin, Low-Molecular-Weight.
Logiparin  0   *Heparin, Low-Molecular-Weight.
ITF 1331  144965-07-1 Heparin, compd. with bis(4-(dibutylamino)butyl) carbonate  Heparin, Low-Molecular-Weight/*analogs & derivatives Factor Xa/antagonists & inhibitors. Haemostasis 1992;22(3):113-6
heparin-dihydergot  0   *Dihydroergotamine *Heparin, Low-Molecular-Weight Drug Combinations. Med Welt 1981;32(25):1021EMBOLEX

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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