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Deoxycholic Acid

More information in Books or onNLM PubMed
Definition: A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.     
Pharmacological Action Cholagogues and Choleretics
Examples Chenodeoxycholic Acid; Glycodeoxycholic Acid; Taurodeoxycholic Acid; Ursodeoxycholic Acid 		Other names Desoxycholic Acid; Deoxycholate; Deoxycholic Acid, 5alpha Isomer; Deoxycholic Acid, 3beta Isomer; Deoxycholic Acid, 12beta Isomer; Deoxycholate, Sodium; Acid, Lagodeoxycholic; Acid, Dihydroxycholanoic; Acid, Desoxycholic; Acid, Deoxycholic; Acid, Choleic; Acid, 5alpha-Isomer Deoxycholic; 5alpha-Isomer Deoxycholic Acid; 3beta-Isomer Deoxycholic Acid; 12beta-Isomer Deoxycholic Acid; Sodium Deoxycholate; Lagodeoxycholic Acid; Dihydroxycholanoic Acid; Deoxycholic Acid, Sodium Salt, 12beta-Isomer; Deoxycholic Acid, Monosodium Salt
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-((norbornyl-2-acetyl)amino)-7,12-dihydroxycholan-24-oic acid  0   *Norbornanes Deoxycholic Acid/*analogs & derivatives. Steroids 2009 Sep;74(9):735-41
LMWH-DOCA conjugate  0   Deoxycholic Acid/*analogs & derivatives Heparin, Low-Molecular-Weight/*analogs & derivatives. J Control Release. 2006 Apr 10;111(3):290-8
3,6-dihydroxy-7-fluorocholanoic acid  0   Deoxycholic Acid/*analogs & derivatives. Toxicol Appl Pharmacol 2006 Jul 15;214(2):199-208
N-deoxychoylethylenediamine  0   Deoxycholic Acid/*analogs & derivatives. J Pharm Sci. 2005 Nov;94(11):2541-8
1-O-(24-deoxycholyl)-2-deoxyglucopyranuronic acid  0   *Glucuronides Deoxycholic Acid/*analogs & derivatives. Lipids 2003 Aug;38(8):873-9
6-fluoro-3,7-dihydroxy-5-cholan-24-oic acid  0   Deoxycholic Acid/*analogs & derivatives. Steroids 2002 Jan;67(1):51-6
3-hydroxy-polydeoxycholic acid  115349-14-9   *Polymers Deoxycholic Acid/*analogs & derivatives. J Lipid Res 1993 Dec;34(12):2121-34
6-hydroxycholanoic acid  77059-14-4   Deoxycholic Acid/*analogs & derivatives. Steroids 1993 Aug;58(8):362-9
3,7-dioxocholanoic acid  28332-53-8   Deoxycholic Acid/*analogs & derivatives. J Pharmacobiodyn 1990;13(10):637
6-methylmurideoxycholic acid  123202-28-8   Deoxycholic Acid/*analogs & derivatives. Gastroenterology 1990;98(2):397
amphotericin B, deoxycholate drug combination  87687-70-5   *Amphotericin B *Deoxycholic Acid Drug Combinations.
Pharma Action Antifungal Agents 		Antimicrob Agents Chemother 1989;33(3):362
hyodeoxycholate-6-O-glucuronide  76060-17-8   Deoxycholic Acid/*analogs & derivatives. J Lipid Res 1987;28(11):1370
deoxycholyltyrosine  103528-66-1   Deoxycholic Acid/*analogs & derivatives. Biochim Biophys Acta 1987;926(2):154
7-methyldeoxycholic acid  109582-23-2 Cholan-24-oic acid, 3,12-dihydroxy-7-methyl-, (3alpha,5beta,12alpha)  Deoxycholic Acid/*analogs & derivatives. Hepatology 1987;7(2):229
dehydrodeoxycholic acid  2958-05-6   Deoxycholic Acid/*analogs & derivatives. J Steroid Biochem 1985;22(6):817
3-sulfodeoxycholic acid  67030-48-2   Deoxycholic Acid/*analogs & derivatives. Am J Physiol 1985;248(4 Pt 1):G485
deoxycholic acid receptor  0   *Receptors, Steroid Deoxycholic Acid. Br J Surg 1983;70(9):549
23-nordeoxycholic acid  53608-86-9 24-Norcholan-23-oic acid, 3,12-dihydroxy-, (3alpha,5beta,12alpha)  Deoxycholic Acid/*analogs & derivatives. J Lipid Res 1981;23(1):211
7-ketodeoxycholic acid  911-40-0 (3 alpha,5 beta,12 alpha)-3,12-dihydroxy-7-oxocholan-24-oic acid  Deoxycholic Acid/*analogs & derivatives. Microbiol Immunol 1979;23(9):839
hyodeoxycholic acid  83-49-8 3 alpha,6 alpha-dihydroxy- 5 beta-cholan-24-oic acid  *Deoxycholic Acid. J Steroid Biochem 1979;11(3):1227; Lipids 11(2):93;1976; Pharmazie 30(1):22;1975; Pharmazie 30(8):506-12;1975; Pharmazie 32(3):146;1977; Steroids 1979;34(6):717; Steroids 32(5):589;1978
desoxybilianic acid  438-06-2   Deoxycholic Acid/*analogs & derivatives.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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