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Ursodeoxycholic Acid

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Definition: An epimer of chenodeoxycholic acid. It is a mammalian bile acid found first in the bear and is apparently either a precursor or a product of chenodeoxycholate. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic.  /biosyn /defic /physiol permitted; urso- refers to its first isol from URSIDAE (Latin ursus)   
Pharmacological Action Cholagogues and Choleretics 		Other names Urso; Deoxyursocholic Acid; Ursodeoxycholate, Sodium; Acid, Ursodeoxycholic; Acid, Ursacholic; Acid, Deoxyursocholic; 3 alpha,7 beta Dihydroxy 5 beta cholan 24 oic Acid; Zambon Brand of Ursodeoxycholic Acid; Vita Brand of Ursodeoxycholic Acid; Ursolvan; Ursolite; Ursogal; Ursofalk; Ursodiol; Ursochol; Ursobilane; Urso Heumann; Ursacholic Acid; Tramedico Brand of Ursodeoxycholic Acid; Sodium UrsodeoxycholateDrugs* : URSO 250; URSODIOL; ACTIGALL; URSO FORTE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
6-ethyl-23-methyl-3,7-dihydroxycholan-24-oic acid  0   Ursodeoxycholic Acid/*analogs & derivatives. J Med Chem 2007 Sep 6;50(18):4265-8
2-methyl-3-(2-((4-nitrooxybutyloxy)carbonyl)vinyl)phenyl ursodeoxycholic acid ester  0   *Nitrates Ursodeoxycholic Acid/*analogs & derivatives. Proc Natl Acad Sci U S A 2001 Jul 17;98(15):8897-902
Bamet-UD2  0   *Organoplatinum Compounds *Ursodeoxycholic Acid. Anticancer Res 2000 Sep-Oct;20(5A):3315-22
diamminebis(ursodeoxycholate(O,O'))platinum(II)  0   *Organoplatinum Compounds Ursodeoxycholic Acid/*analogs & derivatives. Bioconjug Chem 2000 Mar-Apr;11(2):167-74
HS 1183  0   Ursodeoxycholic Acid/*analogs & derivatives. Cancer Lett 1999 Nov 15;146(2):147-53
HS 1030  0   Ursodeoxycholic Acid/*analogs & derivatives. Cancer Lett 1999 Nov 15;146(2):147-53
N''-ursodeoxycholyldiethylene-N,N,N'-triacetic acid  0   Ursodeoxycholic Acid/*analogs & derivatives Calcium. Biol Pharm Bull 1998 Jun;21(6):551-7
isoursodeoxycholic acid  78919-26-3   Ursodeoxycholic Acid/*analogs & derivatives. J Hepatol 1997 Apr;26(4):863-70
5-(7-hydroxy-3-O-phosphonocholyl)aminosalicylic acid  0   *Aminosalicylic Acids Ursodeoxycholic Acid/*analogs & derivatives. Biol Pharm Bull 1997 Apr;20(4):370-5
ursodeoxycholate-3-sulfate  89232-83-7   Ursodeoxycholic Acid/*analogs & derivatives. Dig Dis Sci 1996 Oct;41(10):1953-8
cholane-3,7,24-triol-24-sulfate  0   Ursodeoxycholic Acid/*analogs & derivatives. Biol Pharm Bull 1995 Jan;18(1):28-32
6-fluoro-ursodeoxycholic acid  0   Ursodeoxycholic Acid/*analogs & derivatives. Gastroenterology 1995 Apr;108(4):1204-14
6-methylursodeoxycholic acid  0   Ursodeoxycholic Acid/*analogs & derivatives. J Lipid Res 1994 Dec;35(12):2268-79
24-norursodeoxycholic acid  99697-24-2 24-Norcholan-23-oic acid, 3,7-dihydroxy-, (3alpha,5beta,7beta)  Ursodeoxycholic Acid/*analogs & derivatives. J Biol Chem 1993 May 25;268(15):11239-46
ursodeoxycholylcysteic acid  119059-81-3   Cysteic Acid/*analogs & derivatives Ursodeoxycholic Acid/*analogs & derivatives. J Pharmacobiodyn 1992 Oct;15(10):573-80
ursodeoxycholic acid-3-O-glucuronide  0   Ursodeoxycholic Acid/*analogs & derivatives. J Hepatol 1992 May;15(1-2):77-84
ursodeoxycholic acid 3,7-disulfate  0   Ursodeoxycholic Acid/*analogs & derivatives. J Hepatol 1992 May;15(1-2):77-84
ursodeoxycholyl N-carboxymethylglycine  99956-32-8   Ursodeoxycholic Acid/*analogs & derivatives. J Pharmacobiodyn 1991 Oct;14(10):561-6
3,7-dihydroxy-20,22-methylenecholan-23-oic acid  95498-96-7   Ursodeoxycholic Acid/*analogs & derivatives. Chem Phys Lipids 1991;57(1):97
23-methylursodeoxycholic acid  113301-20-5 Cholane-23-carboxylic acid, 3,7-dihydroxy-, (3alpha,5beta,7beta)  Ursodeoxycholic Acid/*analogs & derivatives. Chem Phys Lipids 1991;57(1):97
3,6-dihydroxy-6-methylcholanoic acid  123202-27-7   Ursodeoxycholic Acid/*analogs & derivatives. J Lipid Res 1989;30(7):1005
3,7-dihydroxy-7-ethylcholanoic acid  124729-57-3   Ursodeoxycholic Acid/*analogs & derivatives. Steroids 1989;53(1-2):97
3,7-dihydroxy-7-n-propylcholanoic acid  124729-58-4   Ursodeoxycholic Acid/*analogs & derivatives. Steroids 1989;53(1-2):97
sarcosylsarcoursodeoxycholic acid  125347-55-9   Ursodeoxycholic Acid/*analogs & derivatives. J Lipid Res 1989;30(5):771
ursodeoxycholic acid N-acetylglucosaminide  122908-04-7 Cholan-24-oic acid, 3-((2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)oxy)-7-hydroxy-, (3alpha,5beta,7beta)  Acetylglucosamine/*analogs & derivatives Ursodeoxycholic Acid/*analogs & derivatives. J Biol Chem 1989;264(22):12989
Ursometh  122018-96-6   *Menthol *Ursodeoxycholic Acid Drug Combinations. Gut 1988;29(4):428
PABA-ursodeoxycholic acid  105877-77-8   4-Aminobenzoic Acid/*analogs & derivatives Ursodeoxycholic Acid/*analogs & derivatives. Hiroshima J Med Sci 1987;36(4):377
homoursodeoxycholic acid  102044-28-0   Ursodeoxycholic Acid/*analogs & derivatives. Steroids 1984;44(6):549
ursodeoxycholic acid 7-oleyl ester  85572-47-0   Ursodeoxycholic Acid/*analogs & derivatives. Boll Chim Farm 1985;124(3):150
sarcoursodeoxycholic acid  88446-87-1   Ursodeoxycholic Acid/*analogs & derivatives. Yakugaku Zasshi 1984;104(5):466
3,7-dihydroxy-7-methylcholanoic acid  91414-09-4 Cholan-24-oic acid, 3,7-dihydroxy-7-methyl-, (3alpha,5beta,7beta)  Ursodeoxycholic Acid/*analogs & derivatives. J Lipid Res 1984;25(4):407
3,7-dihydroxy-22,23-methylenecholan-24-oic acid  89414-91-5   Ursodeoxycholic Acid/*analogs & derivatives. J Med Chem 1984;27(6):746
taurine-ursodeoxycholate conjugate  0   *Taurine *Ursodeoxycholic Acid. J Lipid Res 1981;22(2):254
glycoursodeoxycholic acid  64480-66-6 N-((3 alpha,5 beta,7 beta)-7-hydroxy-24-oxo-3-(sulfooxy) cholan-24-yl)glycine  Ursodeoxycholic Acid/*analogs & derivatives. J Lipid Res 21(1):72;1980

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