encyclopedia of medical concepts
ψ 

L-Iditol 2-Dehydrogenase

More information in Books or onNLM PubMed
Definition: An alcohol oxidoreductase which catalyzes the oxidation of L-iditol to L-sorbose in the presence of NAD. It also acts on D-glucitol to form D-fructose. It also acts on other closely related sugar alcohols to form the corresponding sugar. EC 1.1.1.14      Other names Sorbitol Dehydrogenase; Iditol Dehydrogenase; L Iditol 2 Dehydrogenase; Dehydrogenase, Sorbitol; Dehydrogenase, Polyol; Dehydrogenase, Iditol; 2-Dehydrogenase, L-Iditol; Polyol Dehydrogenase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-(4-(4-(2-(1-hydroxyethyl)pyrimidin-4-yl)-2,6-dimethylpiperazin-1-yl)pyrimidin-2-yl)ethanol  0   *Piperazines *Pyrimidines L-Iditol 2-Dehydrogenase/antagonists & inhibitors. J Med Chem 2002 Jan 17;45(2):511-28
4-(2-hydroxyethylpyrimidin-1-yl)piperazine-1-sulfonic acid dimethylamide  0   *Pyrimidines *Sulfonamides L-Iditol 2-Dehydrogenase/antagonists & inhibitors. J Med Chem 2001 Aug 16;44(17):2695-700
SDI 157  0   *Piperazines *Pyrimidines L-Iditol 2-Dehydrogenase/antagonists & inhibitors. Biochem Pharmacol 1999 Dec 15;58(12):1945-54
2-hydroxymethyl-4-(4-(N,N-dimethylaminosulfonyl)-1-piperazino)pyrimidine  140687-51-0   *Piperazines *Pyrimidines L-Iditol 2-Dehydrogenase/antagonists & inhibitors. Diabetologia 1997 Mar;40(3):271-81
SDI 158  0   *Pyrimidines L-Iditol 2-Dehydrogenase/antagonists & inhibitors. Biochem J 1997 Jan 1;321(Pt 1):239-46
S 0773  0   *Pyrimidines L-Iditol 2-Dehydrogenase/antagonists & inhibitors. Diabetes 1995 Feb;44(2):234-42
TMS1 protein, S pombe  EC 1.1.1.14   *L-Iditol 2-Dehydrogenase *Schizosaccharomyces pombe Proteins. Eur J Biochem 1993 Oct 15;217(2):731-6

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy