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Iduronidase

More information in Books or onNLM PubMed
Definition: An enzyme that hydrolyzes iduronosidic linkages in desulfated dermatan. Deficiency of this enzyme produces Hurler's syndrome. EC 3.2.1.76.  /defic: consider also MUCOPOLYSACCHARIDOSIS I   
See Also Mucopolysaccharidosis I 		Other names alpha L Iduronidase; alpha L Idosiduronase; alpha-L-Iduronidase; alpha-L-IdosiduronaseDrugs* : ALDURAZYME
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
AGT-181  0   *Antibodies, Monoclonal *Iduronidase *Recombinant Fusion Proteins. J Biotechnol. 2009 Oct 26;144(2):135-41
2-carboxy-3,4,5-trihydroxypiperidine  0   *Pipecolic Acids Glucuronidase/antagonists & inhibitors Iduronidase/antagonists & inhibitors. FEBS Lett 1984;176(1):61

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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