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Pipecolic Acids
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Definition
:
Other names
Acids, Pipecolic
Substance
CAS Registry & name
Categories
Source
Drugs
*
nigriventrine
0
*Pipecolic Acids
*Spider Venoms.
Toxicon. 2011 Feb;57(2):266-74
(2S,4R)-
4-
methylpipecolic acid
0
*Pipecolic Acids.
J Org Chem. 2010 Dec 17;75(24):8728-31
6-
methyl-
3-
hydroxypiperidine-
2-
carboxylic acid
0
*Pipecolic Acids
alpha-Galactosidase/antagonists & inhibitors
alpha-Glucosidases/antagonists & inhibitors.
Bioorg Med Chem 2010 Nov 15;18(22):7799-803
1-
(4-
(2-
(5-
methyl-
2-
p-
tolyloxazol-
4-
yl)ethoxy)benzyl)piperidine-
2-
carboxylic acid
0
*Oxazoles
*Pipecolic Acids
PPAR alpha/agonists
PPAR gamma/agonists.
Mol Pharmacol 2010 Nov;78(5):877-85
tubulysin B
0
*Oligopeptides
*Pipecolic Acids.
Org Lett. 2009 Dec 17;11(24):5567-9
Refsum disease with increased pipecolic acidemia
0
*Hepatomegaly
*Refsum Disease
Developmental Disabilities
Pipecolic Acids/urine.
N-
Boc-
(2R,3R)-
3-
methyl-
3-
hydroxypipecolic acid
0
*Pipecolic Acids.
J Org Chem. 2008 Apr 18;73(8):3295-8
3-
hydroxy-
4,5-
dehydropipecolic acid
0
*Pipecolic Acids.
Bioorg Med Chem Lett 2008 Mar 15;18(6):1810-3
3-
hydroxypipecolic acid
0
*Pipecolic Acids.
Bioorg Med Chem Lett 2008 Mar 15;18(6):1810-3
tubulysin V
0
*Oligopeptides
*Pipecolic Acids.
Angew Chem Int Ed Engl. 2006 Nov 6;45(43):7235-9
tubulysin U
0
*Oligopeptides
*Pipecolic Acids.
Angew Chem Int Ed Engl 2006 Nov 6;45(43):7235-9
heptakis(2,3-
dideoxy-
2,3-
epithio)-
beta-
cycloallin
0
*Pipecolic Acids.
Angew Chem Int Ed Engl. 2005 Jul 4;44(27):4201-4
penasulfate A
0
*Fatty Acids
*Pipecolic Acids.
J Nat Prod 2004 Aug;67(8):1346-50
3-
phenylpipecolic acid
0
*Pipecolic Acids.
J Org Chem 2002 Mar 8;67(5):1448-52
1-
(1,1-
dimethylethyl) hydrogen 3-
(3-
(((1,1-
dimethylethyl)diphenylsilyl)oxy)propyl)-
1,2-
piperidinedicarboxylate
0
*Pipecolic Acids.
J Org Chem 2000 Feb 25;65(4):1222-4
4-
phenyl-
1-
(N(alpha)-
(7-
methoxy-
2-
naphthalenesulfonyl)arginyl)-
2-
piperidinecarboxylic acid
0
*Pipecolic Acids
*Sulfonamides.
J Biol Chem 2000 Jun 23;275(25):18995-9
3-
(1-
hydroxy-
2-
phosphonoethyl)-
2-
piperidinecarboxylic acid
0
*Phosphonic Acids
*Pipecolic Acids
Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors.
Bioorg Med Chem 1997 Jul;5(7):1293-9
MDL 100925
138738-21-3
*Phosphonic Acids
*Pipecolic Acids
Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors.
Bioorg Med Chem 1997 Jul;5(7):1293-9
cycasthioamide
0
*Pipecolic Acids.
Phytochemistry 1997 Jun;45(3):517-9
4,5-
dehydropipecolic acid
498-98-6
*Pipecolic Acids.
J Med Chem 1996 Aug 2;39(16):3046-8
4-
hydroxypipecolic acid
14228-16-1
*Pipecolic Acids.
Naunyn Schmiedebergs Arch Pharmacol 1995 Apr;351(4):371-6
2,4,5-
piperidinetricarboxylic acid
0
*Pipecolic Acids
*Tricarboxylic Acids.
Z Naturforsch (C) 1994 Nov-Dec;49(11-12):707-11
LY 221501
145512-35-2 4-
Piperidinebutanoic acid, 2-
carboxy-
, (2R-
cis)
*Pipecolic Acids.
Mol Pharmacol 1992 Oct;42(4):679-86
LY 257883
118183-22-5
*Pipecolic Acids.
Mol Pharmacol 1992 Oct;42(4):679-86
cyclopentenosine
145853-95-8
*Amino Acids
*Pipecolic Acids.
Biochem Biophys Res Commun 1992 Aug 14;186(3):1533-8
delta(2)-
piperidine-
2-
carboxylic acid
99839-26-6
*Pipecolic Acids.
J Biochem (Tokyo) 1991;109(5):705
azacaine
98036-85-2
*Pipecolic Acids
Anesthesia, Conduction
Anesthesia, Epidural.
Klin Khir 1991(1):58
LY 233053
125546-04-5
*Pipecolic Acids
*Tetrazoles.
J Pharmacol Exp Ther 1990;255(3):1301
selfotel
110347-85-8 2-
Piperidinecarboxylic acid, 4-
(phosphonomethyl)-
, cis
*Pipecolic Acids.
Pharma Action
Excitatory Amino Acid Antagonists
Pharmacol Biochem Behav 1987;27(3):553
5-
hydroxypipecolic acid
13096-31-6
*Pipecolic Acids.
Anal Biochem 1987;163(2):303
2-
carboxy-
3,4,5-
trihydroxypiperidine
0
*Pipecolic Acids
Glucuronidase/antagonists & inhibitors
Iduronidase/antagonists & inhibitors.
FEBS Lett 1984;176(1):61
2,4-
piperidinedicarboxylic acid
85819-03-0
*Pipecolic Acids.
Neuropharmacology 1984;23(1):23
2,5-
piperidinedicarboxylic acid
84619-48-7
*Pipecolic Acids.
Neuropharmacology 1984;23(1):23
2,6-
piperidinedicarboxylic acid
499-82-1
*Pipecolic Acids.
Neuropharmacology 1984;23(1):23
delta(1)-
piperidine-
2-
carboxylic acid
2756-89-0
*Pipecolic Acids.
Anal Biochem 1982;125(2):376
4-
methyl-
6-
(2-
oxobutyl)-
2-
piperidinecarboxylic acid
74235-25-9 2-
Piperidinecarboxylic acid, 4-
methyl-
6-
(2-
oxobutyl)-
, (2S-
(2alpha,4alpha,6beta))
*Pipecolic Acids.
J Antibiot (Tokyo) 1982;35(4):543
argatroban
74863-84-6 2-
Piperidinecarboxylic acid, 1-
(5-
((aminoiminomethyl)amino)-
1-
oxo-
2-
(((1,2,3,4-
tetrahydro-
3-
methyl-
8-
quinolinyl)sulfonyl)amino)pentyl)-
4-
methyl
*Pipecolic Acids.
Pharma Action
Antithrombins
;
Platelet Aggregation Inhibitors
Biochem Biophys Res Commun 1981;101(2):440
ARGATROBAN
;
ACOVA
;
ARGATROBAN IN SODIUM CHLORIDE
;
ARGATROBAN IN DEXTROSE
pipecolic acid
535-75-1 2-
piperidinecarboxylic acid
*Pipecolic Acids.
Neurochem Res 1981;6(4):391
6-
oxopiperidine-
2-
carboxylic acid
0
*Pipecolic Acids.
J Antibiot (Tokyo) 1980;33(11):1348
isoguvacine oxide
77736-02-8 7-
Oxa-
3-
azabicyclo(4.1.0)heptane-
6-
carboxylic acid
*Pipecolic Acids.
Adv Biochem Psychopharmacol 1981;29:69
2,3-
piperidinedicarboxylic acid
46026-75-9 2,3-
Piperidinedicarboxylic acid, cis
*Pipecolic Acids.
Pharma Action
Anticonvulsants
;
Excitatory Amino Acid Antagonists
J Neurochem 1981;36(3):1305
ethyl pipecolylacetate
77306-10-6 2-
Piperidinepropanoic acid, beta-
oxo-
, ethyl ester
*Pipecolic Acids.
Biochemistry 18(17):3663;1979
dicolin
382-82-1 piperidinium, 2-
((2-
(diethylmethylammonio)ethoxy)carbonyl)-
1,1,6-
trimethyl-
, diiodide
*Pipecolic Acids
Choline/*analogs & derivatives.
Farmatsiia 1979;28(5):26; Farmatsiia 27(2):26;1978
cycloalliin
455-41-4 3-
Thiomorpholinecarboxylic acid, 5-
methyl-
, 1-
oxide, (1S-
(1alpha,3beta,5beta))
*Pipecolic Acids.
Atherosclerosis 27(3):347;1977
dimecolin
3425-97-6 1,1,6-
trimethyl-
2-
((2-
(trimethylammonio)ethoxy)carbonyl)piperidinium, diiodide
*Pipecolic Acids.
Biull Eksp Biol Med 1980;89(2):232; Farm Zh 31(1):37;1976; Farmatsiia 1979;28(6):24; Farmatsiia 27(2):26;1978; Vrach Delo 3:31;1974