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Kynurenic Acid

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Definition: A broad-spectrum excitatory amino acid antagonist used as a research tool.     
Pharmacological Action Excitatory Amino Acid Antagonists 		Other names Acid, Kynurenic; Kynurenate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-(2-N,N-dimethylaminoethylamine-1-carbonyl)-1H-quinolin-4-one hydrochloride  0   Kynurenic Acid/*analogs & derivatives. J Neural Transm. 2010 Feb;117(2):183-8
3-(2'-pyrrolidinyl)-kynurenic acid  0   *Pyrrolidines Kynurenic Acid/*analogs & derivatives. Magn Reson Chem. 2009 May;47(5):456-9
3-hydroxyquinaldic acid  0   Kynurenic Acid/*analogs & derivatives. Mol Biosyst. 2008 Jun;4(6):622-8
SZR 72  0   Kynurenic Acid/*analogs & derivatives. Neurosci Res 2008 Aug;61(4):429-32
6-hydroxykynurenic acid  0   Kynurenic Acid/*analogs & derivatives. J Neurochem 2001 May;77(4):1108-15
4-quinolone-2-carboxylic acid  0   *Kynurenic Acid. J Nat Prod 1998 Feb;61(2):262-3
7-chloro-5-iodokynurenic acid  0   Kynurenic Acid/*analogs & derivatives Iodine Radioisotopes. Appl Radiat Isot 1997 Sep;48(9):1173-7
4,6-dichlorokynurenine  0   Kynurenic Acid/*analogs & derivatives. Neuroreport 1996 Dec 20;8(1):15-8
7-chlorothiokynurenic acid  135025-56-8   Kynurenic Acid/*analogs & derivatives. J Pharmacol Exp Ther 1993 Nov;267(2):937-41
5-chlorothiokynurenic acid  136036-87-8   Kynurenic Acid/*analogs & derivatives. J Pharmacol Exp Ther 1993 Nov;267(2):937-41
thiokynurenate  135025-53-5   Kynurenic Acid/*analogs & derivatives. Pharmacol Res 1992 Feb-Mar;25(Suppl 1):33-4
5,7-dichlorokynurenic acid  131123-76-7   Kynurenic Acid/*analogs & derivatives.
Pharma Action Excitatory Amino Acid Antagonists 		Mol Pharmacol 1990;38(4):554
7-chlorokynurenic acid  18000-24-3   Kynurenic Acid/*analogs & derivatives Receptors, Glycine/antagonists & inhibitors.
Pharma Action Excitatory Amino Acid Antagonists ; Neuroprotective Agents 		Proc Natl Acad Sci USA 1988;85(17):6547
4,6,8-trihydroxyquinaldic acid  0   Kynurenic Acid/*analogs & derivatives. Wakayama Med Rep 14(4):139;1971

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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