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Lysosomes

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Definition: A class of morphologically heterogeneous cytoplasmic particles in animal and plant tissues characterized by their content of hydrolytic enzymes and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured. Such rupture is supposed to be under metabolic (hormonal) control. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)  A 11 qualif except /cytol; /genet permitted   
Examples Acrosome
Other names Lysosome
 
SubstanceCAS Registry & nameCategoriesSource
NCU-G1 protein, mouse  0   *Membrane Proteins Lysosomes. Biochem J 2009 Aug 15;422(1):83-90
WDR48 protein, human  0   *Proteins Lysosomes. Immunity 2002 Aug;17(2):221-33
Laptm5 protein, rat  0   *Membrane Proteins *Nerve Tissue Proteins *Apoptosis Regulatory Proteins Lysosomes Microglia. Brain Res Mol Brain Res 2001 Mar 31;88(1-2):1-13
Kif2b protein, mouse  0   *Kinesin Lysosomes. EMBO J 1998 Oct 15;17(20):5855-67
Lgp107 protein, rat  0   *Sialoglycoproteins *Lysosome-Associated Membrane Glycoproteins Lysosomes. Histochemistry 1993 Aug;100(2):93-9
SCARB2 protein, human  0   *Receptors, Scavenger *Lysosome-Associated Membrane Glycoproteins Lysosomes Sialoglycoproteins. Biochem Biophys Res Commun 1992 Apr 30;184(2):604-11
lysosomal proteins  0   *Proteins Lysosomes. Z Exp Chir 11(6):375;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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