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Kinesin

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Definition: A microtubule-associated mechanical adenosine triphosphatase, that uses the energy of ATP hydrolysis to move organelles along microtubules toward the plus end of the microtubule. The protein is found in squid axoplasm, optic lobes, and in bovine brain. Bovine kinesin is a heterotetramer composed of two heavy (120 kDa) and two light (62 kDa) chains. EC 3.6.1.-.  a microtubule-associated protein   
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
EMD 534085  0   *Quinolines Kinesin/antagonists & inhibitors. Bioorg Med Chem Lett 2010 Mar 1;20(5):1491-5
kinesin family member 16B  EC 3.6.1.-   *Kinesin. Dev Cell. 2011 Jan 18;20(1):60-71
KIF18B protein, human  EC 3.6.1.-   *Kinesin. Gene. 2010 Oct 15;466(1-2):16-25
fluorastrol  0   *Pyrimidines *Thiones Kinesin/antagonists & inhibitors. J Med Chem 2010 Aug 12;53(15):5676-83
KIF21B protein, human  EC 3.6.1.-   *Kinesin. Hum Mol Genet 2010 Mar 1;19(5):953-62
MCAK protein, mouse  EC 3.6.1.-   *Kinesin *Cell Cycle Proteins. Development 2010 Jul;137(13):2133-8
KAC2 protein, Arabidopsis  EC 3.6.1.-   *Kinesin *Arabidopsis Proteins. Proc Natl Acad Sci U S A 2010 May 11;107(19):8860-5
KAC1 protein, Arabidopsis  EC 3.6.1.-   *Kinesin *Arabidopsis Proteins. Proc Natl Acad Sci U S A 2010 May 11;107(19):8860-5
Kif5A protein, rat  EC 3.6.1.-   *Kinesin. Neuron 2010 Jan 14;65(1):53-65
KLP59D protein, Drosophila  EC 3.6.1.-   *Kinesin *Drosophila Proteins. Mol Biol Cell 2009 Nov;20(22):4696-705
Kif7 protein, mouse  EC 3.6.1.-   *Kinesin. Proc Natl Acad Sci U S A 2009 Aug 11;106(32):13377-82
KIF1B protein, zebrafish  EC 3.6.1.-   *Kinesin *Zebrafish Proteins. Nat Genet 2009 Jul;41(7):854-8
MKLP1 protein, mouse  EC 3.6.1.-   *Kinesin. Biol Reprod 2009 Mar;80(3):449-57
KIF4 protein, rat  EC 3.6.1.-   *Kinesin. J Biol Chem 2009 Apr 3;284(14):9489-97
MRH2 protein, Arabidopsis  EC 3.6.1.-   *Kinesin *Arabidopsis Proteins. PLoS ONE 2007;2(10):e1074
Kif17 protein, zebrafish  EC 3.6.1.-   *Kinesin *Zebrafish Proteins. Dev Biol 2008 Apr 1;316(1):160-70
nephrocystin-3, mouse  EC 3.6.1.-   *Kinesin. Am J Hum Genet 2008 Apr;82(4):959-70
nephrocystin-3, human  EC 3.6.1.-   *Kinesin. Am J Hum Genet 2008 Apr;82(4):959-70
KAP3A protein, human  EC 3.6.1.-   *Kinesin Protein Subunits. Cell Signal 2008 Feb;20(2):432-42
Kid protein, mouse  EC 3.6.1.-   *DNA-Binding Proteins *Kinesin. Cell 2008 Mar 7;132(5):
KIF6 protein, human  EC 3.6.1.-   *Kinesin. J Am Coll Cardiol 2008 Jan 29;51(4):435-43
kinesin 2 protein, Drosophila  EC 3.6.1.-   *Kinesin *Drosophila Proteins. RNA 2007 Nov;13(11):1860-7
Pakrp1l protein, Arabidopsis  EC 3.6.1.-   *Kinesin *Arabidopsis Proteins. Plant Cell 2007 Aug;19(8):2595-605
KIF2B protein, human  EC 3.6.1.-   *Kinesin. Mol Biol Cell 2007 Aug;18(8):2970-9
KIF2 protein, Xenopus  EC 3.6.1.-   *Kinesin *Xenopus Proteins. Curr Biol 2007 Jun 5;17(11):953-9
KIF5B protein, rat  0   *Kinesin. J Neurosci 2007 Jul 4;27(27):7284-96
Eg5 protein, mouse  EC 3.6.1.-   *Kinesin. Biochem Biophys Res Commun 2007 Jun 8;357(3):694-9
kinesin-1 protein, Drosophila  EC 3.6.1.-   *Kinesin *Drosophila Proteins. Proc Natl Acad Sci U S A 2006 Oct 24;103(43):15812-7
KIF5C protein, human  EC 3.6.1.-   *Kinesin. J Biol Chem 2006 Sep 15;281(37):27216-28
KIF13B protein, human  EC 3.6.1.-   *Kinesin. J Cell Biol 2006 Jul 31;174(3):425-36
POK2 protein, Arabidopsis  EC 3.6.1.-   *Kinesin *Arabidopsis Proteins. Curr Biol 2006 May 9;16(9):888-94
POK1 protein, Arabidopsis  EC 3.6.1.-   *Kinesin *Arabidopsis Proteins. Curr Biol 2006 May 9;16(9):888-94
KIF2A protein, human  0   *Kinesin.
mitotic centromere-associated kinesin, Xenopus  0   *Kinesin *Xenopus Proteins. Mol Biol Cell 2006 Feb;17(2):700-10
Kif5A protein, mouse  0   *Kinesin. J Mol Biol 2005 Dec 9;354(4):872-82
KP1 protein, Arabidopsis thaliana  0   *Kinesin *Arabidopsis Proteins. Cell Res 2005 Sep;15(9):725-33
KIF13B protein, rat  EC 3.6.1.-   *Kinesin. J Cell Sci 2005 Jun 1;118(Pt 11):2471-84
KIF16B protein, human  0   *Kinesin. Cell 2005 May 6;121(3):437-50
KIF12 protein, mouse  0   *Kinesin. J Am Soc Nephrol 2005 Apr;16(4):905-16
ATK5 protein, Arabidopsis  EC 3.6.1.-   *Kinesin *Arabidopsis Proteins. Mol Biol Cell 2005 Apr;16(4):1584-92
Kif11 protein, rat  EC 3.6.1.-   *Kinesin. Cell Motil Cytoskeleton 2005 Apr;60(4):181-90
MCAK protein, C elegans  EC 3.6.1.-   *Kinesin *Caenorhabditis elegans Proteins. Mol Biol Cell 2005 Mar;16(3):1056-70
KIF18A protein, human  EC 3.6.1.-   *Kinesin. Gene 2005 May 23;351:19-28
kinesin light chain 1 protein, C elegans  0   *Kinesin *Cell Cycle Proteins *Caenorhabditis elegans Proteins. J Cell Biol 2005 May 9;169(3):447-57
UNC-116 protein, C elegans  0   *Kinesin *Cell Cycle Proteins *Caenorhabditis elegans Proteins. J Cell Biol 2005 May 9;169(3):447-57
KIF14 protein, human  EC 3.6.1.-   *Oncogene Proteins *Kinesin. Oncogene 2005 Jul 14;24(30):4741-53
KIF7 protein, human  0   *Kinesin.
KLP-6 protein, C elegans  EC 3.6.1.-   *Kinesin *Caenorhabditis elegans Proteins. Curr Biol 2005 Mar 8;15(5):394-404
KIF5A protein, human  0   *Kinesin. Neurology. 2004 Sep 28;63(6):1108-10
costal2 protein, zebrafish  0   *Kinesin *Zebrafish Proteins Signal Transduction. Development 2005 Feb;132(4):625-34
MYLK protein, human  EC 2.7.11.18   *Calcium-Binding Proteins *Myosin-Light-Chain Kinase Kinesin.
xklp3A protein, Xenopus  0   *Kinesin *Xenopus Proteins.
XKLP3 protein, Xenopus  0   *Kinesin *Xenopus Proteins.
klp-11 protein, C elegans  0   *Kinesin *Caenorhabditis elegans Proteins.
KIF12 protein, human  0   *Kinesin. Oncol Rep. 2005 Feb;13(2):367-70
KIF27 protein, human  0   *Kinesin. Int J Oncol. 2004 Dec;25(6):1875-80
KLP-19 protein, C elegans  0   *Kinesin *Caenorhabditis elegans Proteins. J Cell Biol 2004 Sep 27;166(7):991-1001
Xkid protein, Xenopus  0   *DNA-Binding Proteins *Kinesin *Xenopus Proteins.
Kif3b protein, mouse  0   *Kinesin.
AF-6 protein, C elegans  0   *Myosins *Kinesin *Caenorhabditis elegans Proteins.
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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