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Motilin

More information in Books or onNLM PubMed
Definition: A peptide of about 22-amino acids isolated from the DUODENUM. At low pH it inhibits gastric motor activity, whereas at high pH it has a stimulating effect.     
Pharmacological Action Gastrointestinal Agents
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
atilmotin  0   *Motilin *Peptide Fragments Motilin/agonists. Neurogastroenterol Motil 2006 Jan;18(1):1-5
SK896  0   Motilin/*analogs & derivatives. Eur J Pharmacol. 2000 Jul 28;401(1):97-107
OHM 11526  0   Motilin/*analogs & derivatives. Eur J Pharmacol 1995 Nov 24;286(3):241
biotinyl(Cys(23))motilin  0   Biotin/*analogs & derivatives Motilin/*analogs & derivatives. Peptides 1994;15(2):257-62
ANQ 11125  153966-48-4 ANQ 11125  Motilin/*antagonists & inhibitors. Biochem Biophys Res Commun 1994 Jan 28;198(2):411-6
pMot (1-14), Leu(13)  138143-07-4   *Peptide Fragments Motilin/*analogs & derivatives. Peptides 1992 Nov-Dec;13(6):1103-7
motilin-associated peptide  0   *Peptides Motilin. Biochim Biophys Acta 1992 Jul 15;341-4
prepromotilin  112820-96-9 Motilin, prepro  *Motilin *Protein Precursors. Synapse 1988;2(3):266
13-Leu-motilin  59530-69-7   Motilin/*analogs & derivatives. Hoppe Seylers Z Physiol Chem 357(3):447-67;1976
motilin, Nle(13)  55524-56-6   Motilin/*analogs & derivatives. Am J Dig Dis 21(9):789;1976; Gastroenterology 68(6):1485;1975; Gastroenterology 72:413;1977; Gut 17(5):362;1976; Hoppe Seylers Z Physiol Chem 357(3):447;1976; Hoppe Seylers Z Physiol Chem 357(3):459;1976; Hoppe Seylers Z Physiol Chem 357(3):467;1976; Scand J Gastroenterol 10(2):199;1975; Scand J Gastroenterol 11(1):93;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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