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Oxidoreductases, O-Demethylating

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Definition: Drug metabolizing enzymes which oxidize methyl ethers. Usually found in liver microsomes.     
Examples Nitroanisole O-Demethylase 		Other names O-Demethylating Oxidoreductases; O Demethylating Oxidoreductases; O Demethylases; Demethylating Oxidoreductases, O; Oxidoreductases, O Demethylating; O-Demethylases
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
dicamba O-demethylase  EC 1.-   *Oxidoreductases, O-Demethylating. J Biol Chem 2005 Jul 1;280(26):24759-67
ligX protein, Sphingomonas paucimobilis  EC 1.-   *Bacterial Proteins *Oxidoreductases, O-Demethylating. Appl Environ Microbiol 2000 May;66(5):2125-32
methyl-CpG DNA demethylase  EC 1.-   *Oxidoreductases, O-Demethylating. Nature 1999 Feb 18;397(6720):579-83
scoparone O-demethylase  EC 1.-   *Cytochrome P-450 Enzyme System *Oxidoreductases, O-Demethylating. Biol Pharm Bull 1993 Jan;16(1):90-2
pisatin demethylase  EC 1.14.99.-   *Cytochrome P-450 Enzyme System *Oxidoreductases, O-Demethylating. Gene 1988;68(2):335
methoxyphenamine O-demethylase  EC 1.-   *Oxidoreductases, O-Demethylating. Pharmacol Ther 1987;33(1):73
dextromethorphan O-demethylase  EC 1.-   *Cytochrome P-450 Enzyme System *Oxidoreductases, O-Demethylating Cytochrome P-450 CYP2D6. Anal Biochem 1987;162(1):24
7-methoxycoumarin-O-demethylase  EC 1.-   *Oxidoreductases, O-Demethylating. Xenobiotica 1985;15(8-9):681
veratrate 3-O-demethylase  EC 1.14.99.-   *Oxidoreductases, O-Demethylating. Acta Biochim Pol 1984;31(4):383
guaiacol glycerol ether O-demethylase  EC 1.-   *Oxidoreductases, O-Demethylating. Arch Toxicol 1980;45(2):149
2-methoxyestrogen demethylase  EC 1.-   *Oxidoreductases, O-Demethylating. Endocrinology 1980;107(4):1192
4-nitroanisole O-demethylase  EC 1.-   *Oxidoreductases, O-Demethylating. J Biochem (Tokyo) 1980;87(5):1457
norcodeine O-demethylase  EC 1.-   *Oxidoreductases, O-Demethylating. J Pharmacol Exp Ther 1980;213(1):28
vanillate O-demethylase  EC 1.14.13.82   *Oxidoreductases, O-Demethylating. Microbios 3(9):113;1971
methyl etherase  EC 1.-   *Oxidoreductases, O-Demethylating.
methoxyphenol-O-demethylase  EC 1.-   *Oxidoreductases, O-Demethylating. Comp Biochem Physiol 53(1c):37;1976
4-methoxybenzoate monooxygenase (O-demethylating)  EC 1.14.99.15   *Oxidoreductases, O-Demethylating. Eur J Biochem 72:107;1977; Eur J Biochem 92(1):209;1978; Microbiol Rev 43(3):384;1979; Microbios 3(9):113;1971
dichloro-p-nitroanisole O-demethylase  EC 1.-   *Oxidoreductases, O-Demethylating. Biochem Pharmacol 27(8):1129;1978
3-O-demethylases  EC 1.-   *Oxidoreductases, O-Demethylating. Microbios 19(16):89;1978
anisole O-demethylase  EC 1.-   *Oxidoreductases, O-Demethylating. Int J Biochem 9(1):63;1978

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