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Oxymorphone

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Definition: An opioid analgesic with actions and uses similar to those of MORPHINE, apart from an absence of cough suppressant activity. It is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1092)     
Pharmacological Action Adjuvants, Anesthesia; Analgesics, Opioid; Narcotics 		Other names Hydrochloride, Oxymorphone; Oxymorphone Hydrochloride; Numorphan; Endo Brand of Oxymorphone Hydrochloride; Bristol-Myers Squibb Brand of Oxymorphone HydrochlDrugs* : OPANA ER; OPANA; OXYMORPHONE HYDROCHLORIDE; NUMORPHAN
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
14-O-methyloxymorphone  0   Oxymorphone/*analogs & derivatives. Brain Res Bull. 2010 Jan 15;81(1):178-84
14-benzyloxy-4,5-epoxy-3-hydroxy-17-methylmorphinan-6-one  0   Oxymorphone/*analogs & derivatives Receptors, Opioid, mu/agonists. J Med Chem 2005 May 5;48(9):3372-8
oxymorphone-3-glucuronide  0   *Glucuronides Oxymorphone/*analogs & derivatives. Pharmacotherapy 2004 Apr;24(4):468-76
4,5-epoxy-3,6,14-trihydroxy-17-methylmorphinan  0   Oxymorphone/*analogs & derivatives. Pharmacotherapy 2004 Apr;24(4):468-76
Mr 2264  148708-26-3   Oxymorphone/*analogs & derivatives. Eur J Clin Pharmacol 1994;46(4):301-4
7-spiroindanyloxymorphone  150380-34-0   *Spiro Compounds Oxymorphone/*analogs & derivatives. J Med Chem 1993 Aug 20;36(17):2572-4
oxymorphone-6-spirohydantoin  123016-74-0   *Hydantoins Oxymorphone/*analogs & derivatives. Pharmacol Biochem Behav 1989;32(4):939
oxymorphone 4-nitrophenylhydrazone  101365-17-7   Hydrazones Oxymorphone/*analogs & derivatives. J Pharmacol Exp Ther 1988;245(1):8
oxymorphone phenylhydrazone  101365-15-5   *Hydrazones Oxymorphone/*analogs & derivatives. J Pharmacol Exp Ther 1988;245(1):8
oxymorphone-naltrexonazine  110320-71-3   Naltrexone/*analogs & derivatives Oxymorphone/*analogs & derivatives. Life Sci 1987;41(6):783
oxymorphone-3-methoxynaltrexonazine  110320-72-4   Naltrexone/*analogs & derivatives Oxymorphone/*analogs & derivatives. Life Sci 1987;41(6):783
10-ketooxymorphone  96445-15-7   Oxymorphone/*analogs & derivatives. J Med Chem 1985;28(7):974
4,5-epoxy-3,6,14-trihydroxy-6-(2-carboxyallyl)-17-methylmorphinan gamma-lactone  92398-22-6   Oxymorphone/*analogs & derivatives. J Med Chem 1984;27(12):1718
6-fluoro-6-desoxyoxymorphone  92593-44-7 Morphinan-3,14-diol, 4,5-epoxy-6-fluoro-17-methyl-, (5alpha,6beta)  Oxymorphone/*analogs & derivatives. Neuropeptides 1984;4(4):311
oxymorphamine  84800-62-4 Morphinan-3,14-diol, 6-amino-4,5-epoxy-17-methyl-, (5alpha)  Oxymorphone/*analogs & derivatives. Life Sci 1982;31(12-13):1283
oxymorphonazine  82824-00-8 Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-methyl-, ((5alpha)-4,5-epoxy-3,14-dihydroxy-17-methylmorphinan-6-ylidene)hydrazone, (5alpha)  Oxymorphone/*analogs & derivatives. J Neurosci 1982;2(5);572
oxymorphazone  73697-35-5   Oxymorphone/*analogs & derivatives. J Neurosci 1982;2(5):572
oxymorphone fumarate methyl ester  72782-06-0 2-Butenoic acid, 4-(((5alpha,6beta)-4,5-epoxy-3,14-dihydroxy-17-methylmorphinan-6-yl)amino)-4-oxo-, methyl ester, monohydrochloride, (E)  Oxymorphone/*analogs & derivatives. J Med Chem 1980;23(3):233
chloroxymorphamine  71360-45-7 Morphinan-3,14-diol, 6-(bis(2-chloroethyl)amino)-4,5-epoxy-17-methyl-, (5alpha,6beta)  *Nitrogen Mustard Compounds Oxymorphone/*analogs & derivatives. Science 204(4390):316;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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