encyclopedia of medical concepts
ψ 

Hydantoins

More information in Books or onNLM PubMed
Definition: Compounds based on imidazolidine dione. Some derivatives are ANTICONVULSANTS.     
Examples Allantoin; Dantrolene; Mephenytoin; Phenytoin; Thiohydantoins 		Other names Imidazolidine 2,4 Diones; Imidazolidine-2,4-Diones
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-cyclopropyl-1-(4-(6-(1,1-dioxo-1gamma6-thiomorpholin-4-ylmethyl)-5-fluoro-pyridin-2-yl)benzyl)imidazolidine-2,4-dione  0   *Cyclic S-Oxides *Hydantoins Receptor, Cannabinoid, CB2/agonists. J Med Chem. 2011 Oct 27;54(20):7350-62.
3-(4-chlorobenzyl)-5-(4-nitrobenzylidene)imidazolidine-2,4-dione  0   *Hydantoins. AAPS PharmSciTech 2011 Mar;12(1):401-10
5-hydroxy-5-methylhydantoin  0   *Hydantoins. J Biol Chem 1984 May 10;259(9):5543-8
5-methyl-5(4-pyridyl)hydantoin  0   *Hydantoins *Pyridines. Arch Pharm (Weinheim). 2011 Apr;344(4):209-16
5-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)-2,4-imidazolidinedione  0   *Hydantoins *Pyrazoles. Chem Biol 2011 Feb 25;18(2):177-86
4-hydroxyphenylmethylene hydantoin  0   *Benzylidene Compounds *Hydantoins. Nat Prod Commun 2010 Oct;5(10):1623-6
3-(5-methyl-5-hydantoinyl)acetanilide  0   *Acetanilides *Hydantoins. J Biomed Mater Res A 2009 Nov;91(2):385-90
spiroiminodihydantoin nucleoside  0   *Hydantoins *Nucleosides. Bioorg Med Chem Lett 2009 Sep 1;19(17):4944-7
3-(2-(3-(2-chloroethyl)-3-nitrosouriedo)ethyl)spiro(5,9'-fluorenyl)imidazolidiine-2,4-dione  0   *Hydantoins *Nitrosourea Compounds. Oncol Res 2009;17(9):387-96
3-amino-5-methyl-5-phenylhydantoin  0   *Hydantoins. Ann N Y Acad Sci 2009 Aug;1171:649-58
5-carboxamido-5-formamido-2-iminohydantoin  0   *Hydantoins. J Am Chem Soc 2009 May 6;131(17):6114-23
UPR1024  0   *Benzylidene Compounds *Hydantoins. Mol Cancer Ther 2008 Feb;7(2):361-70
DOTA-1-(4-aminobutyl)-5-(4-bromobenzyl)-3-(3,5-dichlorophenyl)-5-methylimidazolidine-2,4-dione  0   *Hydantoins. Cancer Biother Radiopharm 2006 Oct;21(5):418-26
5-(3,5-diiodo-4-(3-isopropyl-4-hydroxyphenoxy)benzyl)imidazolidine-2,4-dione  0   *Hydantoins Thyroid Hormone Receptors alpha/agonists. ACS Chem Biol 2006 Oct 24;1(9):585-93
guanidinohydantoin-2'-deoxynucleoside-5'-triphosphate  0   *Hydantoins *Nucleotides. J Org Chem 2006 Mar 3;71(5):2181-4
spiroiminodihydantoin-2'-deoxynucleoside-5'-triphosphate  0   *Hydantoins *Nucleotides. J Org Chem 2006 Mar 3;71(5):2181-4
3'-aminocyclohexanespiro-5'-hydantoin  0   *Hydantoins *Spiro Compounds. Acta Crystallogr C 2005 Aug;61(Pt 8):o524-6
5,5'-ethylenebis(5-methyl-3-(3-triethoxysilylpropyl)hydantoin)  0   *Hydantoins *Silanes. Biomaterials 2006 Sep;27(27):4825-30
1-(2-deoxypentofuranosyl)-5-hydroxyhydantoin  0   *Hydantoins *Pentoses. Nucleic Acids Res 2006;34(13):3660-9
glucopyranose spirohydantoin  0   *Hydantoins Glucose/*analogs & derivatives Glycogen Phosphorylase/antagonists & inhibitors. Proteins 2005 Dec 1;61(4):966-83
5-hydroxy-1-(2'-deoxyribofuranosyl)hydantoin  0   *Hydantoins *Nucleosides. Chem Res Toxicol 2005 Aug;18(8):1332-8
1-aminohydantoin  0   *Hydantoins. Food Addit Contam 2005 May;22(5):406-14
spirodihydantoin  0   *Hydantoins *Spiro Compounds. Org Lett 2004 Sep 16;6(19):3417-20
S 3429  0   *Hydantoins *Phenylurea Compounds Integrin alpha4beta1/antagonists & inhibitors. J Heart Lung Transplant 2004 Nov;23(11):1266-76
3-(3-(N,N-dimethyl)aminopropyl)spiro((dihydroimidazo-2,4-dione)-5,3'-(2',3'-dihydrothieno(2,3-b)naphtho-4',9'-dione))  0   *Hydantoins *Naphthoquinones. J Med Chem 2005 Feb 24;48(4):1152-7
7'-hydroxy-2',3'-dihydro-1'H,2H,5H-spiro(imidazolidine-4,4'-quinoline)-2,5-dione  0   *Hydantoins *Spiro Compounds. Bioorg Med Chem 2003 Nov 17;11(23):5059-68
5-methyl-5-phenylhydantoin Pt(II)  0   *Hydantoins *Organoplatinum Compounds. Eur J Med Chem. 2003 Jun;38(6):627-32
dehydroguanidinohydantoin  0   *Guanidines *Hydantoins. Chem Res Toxicol. 2002 Dec;15(12):1643-51
3-methyl-5-isopropylhydantoin  0   *Hydantoins. Int Arch Occup Environ Health 2002 Oct;75 Suppl:S93-6
guanidinohydantoin  0   *Guanidines *Hydantoins. Nucleic Acids Res 2001 May 1;29(9):1967-74
7,8-benzo-1,3-diazaspiro-(4,5)-decane-2,4-dione  0   *Hydantoins *Spiro Compounds. Pol J Pharmacol 2001 Jul-Aug;53(4):395-401
C-2-thioxo-hydantocidin  0   *Hydantoins. Carbohydr Res 2001 Oct 8;335(3):147-50
5-(3,4-dichlorophenyl)methylhydantoin  0   *Hydantoins. Antiviral Res 2000 Oct;48(1):61-9
glucopyranosylidene-spiro-hydantoin  0   *Hydantoins *Spiro Compounds Phosphorylases/antagonists & inhibitors. Bioorg Med Chem Lett 1999 May 17;9(10):1385-90
RU 58642  0   *Hydantoins. J Steroid Biochem Mol Biol 1998 Jan;64(1-2):103-11
5-methyl-5-phenylhydantoin  6843-49-8   *Hydantoins. J Pharm Biomed Anal 1997 Jun;15(9-10):1577-84
5'-phosphohydantocidin  0   *Hydantoins *Pentosephosphates Adenylosuccinate Synthase/antagonists & inhibitors. Plant Physiol 1997 Jun;114(2):549-55
5-phenylhydantoin  89-24-7   *Hydantoins. Enzyme Microb Technol 1996 Apr;18(5):353-7
N-acetyl-5'-phosphohydantocidin  0   *Hydantoins *Pentosephosphates Adenylosuccinate Synthase/antagonists & inhibitors. Plant Physiol 1996 Mar;110(3):753-8
3-((2-cyclohexyl-2-hydroxyethylidene)amino)-2,5-dioxo-4-imidazolidineheptanoic acid  160524-27-6   *Hydantoins. Arch Pharm (Weinheim) 1994 May;327(5):307-17
ethotoin  86-35-1 2,4-Imidazolidinedione, 3-ethyl-5-phenyl  *Hydantoins.
Pharma Action Anticonvulsants 		PEGANONE
cypenhymustine  150380-35-1 1,3-Diazaspiro(4.4)nonane-2,4-dione, 3-(2-(bis(2-chloroethyl)amino)ethyl)  *Hydantoins *Nitrogen Mustard Compounds. Cancer Lett 1993 Jun 15;70(1-2):1-6
AL 4114  139911-05-0   *Fluorenes *Hydantoins *Spiro Compounds Aldehyde Reductase/antagonists & inhibitors. Drug Metab Dispos Biol Fate Chem 1992 Nov-Dec;20(6):948-53
FCE 24220  121532-44-3   *Ergolines *Hydantoins. Drug Metabol Drug Interact 1992;10(3):185-97
AL 3152  126048-33-7 Spiro(9H-fluorene-9,4'-imidazolidine)-2',5'-dione, 2,7-difluoro-4-methoxy  *Fluorenes *Hydantoins Aldehyde Reductase/antagonists & inhibitors. Pharm Res 1992 Apr;9(4):469-73
5-(methoxymethylene)-2,4-imidazolidinedione  136308-39-9   *Hydantoins. Acta Crystallogr C 1992 Mar 15;48(Pt 3):477-80
valine methylhydantoin  0   *Hydantoins. Med Sci Law 1991 Oct;31(4):289-93
5-(2-methylthioethyl)hydantoin  13253-44-6 2,4-Imidazolidinedione, 5-(2-(methylthio)ethyl)  *Hydantoins. J Bacteriol 1992 Feb;174(3):962-9
hydantocidin  130607-26-0 6-Oxa-1,3-diazaspiro(4.4)nonane-2,4-dione, 8,9-dihydroxy-7-(hydroxymethyl)-, (5S-(5alpha,7alpha,8beta,9beta))  *Hydantoins. J Antibiot (Tokyo) 1991;44(3):293
M 16209  128851-36-5 2,4-Imidazolidinedione, 1-((3-bromo-2-benzofuranyl)sulfonyl)  *Benzofurans *Hydantoins Aldehyde Reductase/antagonists & inhibitors. Jpn J Pharmacol 1990;54(4):355
M 16287  128851-55-8 2,4-Imidazolidinedione, 1-((3-chloro-2-benzofuranyl)sulfonyl)  *Benzofurans *Hydantoins Aldehyde Reductase/antagonists & inhibitors. Jpn J Pharmacol 1990;54(4):355
5-indolylmethylhydantoin  108605-53-4   *Hydantoins. J Biotechnol 1990;14(3-4):363
5-(3-indolylmethyl)-3-N-methylhydantoin  74311-00-5   *Hydantoins. J Biotechnol 1990;14(3-4):345
1-(5-(carboxyphenylthio)-2-thenylideneamino)hydantoin  126384-99-4   *Benzoates *Hydantoins Schiff Bases. Farmaco 1989;44(12):1217
oxymorphone-6-spirohydantoin  123016-74-0   *Hydantoins Oxymorphone/*analogs & derivatives. Pharmacol Biochem Behav 1989;32(4):939
5-(2-methoxyphenyl)methylenehydantoin  21730-69-8   *Hydantoins. Jpn J Pharmacol 1989;49(3):309
5-phenylmethylenehydantoin  3775-01-7   *Hydantoins. Jpn J Pharmacol 1989;49(3):309
FCE 22716  95688-34-9   *Ergolines *Hydantoins. Pharmacology 1989;38(2):78
BW A868C  118675-50-6 4-Imidazolidineheptanoic acid, 3-((2-cyclohexyl-2-hydroxyethyl)amino)-2,5-dioxo-1-(phenylmethyl)  *Hydantoins Receptors, Prostaglandin/antagonists & inhibitors.
Pharma Action Platelet Aggregation Inhibitors 		Br J Pharmacol 1989;96(2):291
5-hydroxy-1-methylhydantoin  84210-26-4   *Hydantoins. Biochim Biophys Acta 1988;967(3):441
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy