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Oxyphenbutazone

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Definition: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)  a non-steroidal anti-inflamm agent   
Pharmacological Action Anti-Inflammatory Agents, Non-Steroidal
Other names Tanderil; Oxyphenylbutazone; Novartis Ophthalmics Brand of Oxyphenbutazone; Diflamil; Belmac Brand of Oxyphenbutazone; HydroxyphenylbutazoneDrugs* : OXYPHENBUTAZONE; TANDEARIL
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-hydroxy-oxyphenbutazone  0   Oxyphenbutazone/*analogs & derivatives. Eur Cytokine Netw. 2005 Jun;16(2):144-51
4-hydroxyphenylbutazone  16860-43-8   Oxyphenbutazone/*analogs & derivatives. Acta Pharm Hung 1980;50(4):173
kymalzone  0   *Oxyphenbutazone *Peptide Hydrolases Drug Combinations. Ann Otolaryngol Chir Cervicofac 1980;97(12):1065

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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