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Peptide Hydrolases
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Definition
: Hydrolases that specifically cleave the peptide bonds found in PROTEINS and PEPTIDES. Examples of sub-subclasses for this group include EXOPEPTIDASES and ENDOPEPTIDASES.
Examples
Aspartic Acid Proteases
;
ATP-Dependent Proteases
;
Cathepsins
;
Cysteine Proteases
;
Endopeptidases
;
Exopeptidases
;
Metalloproteases
;
Proprotein Convertases
;
Proteasome Endopeptidase Complex
;
Serine Proteases
Other names
Proteolytic Enzymes; Proteinases; Proteases; Peptidases; Esteroproteases
Substance
CAS Registry & name
Categories
Source
Drugs
*
ALV003
EC 3.4.-
*Peptide Hydrolases
Celiac Disease/drug therapy.
Dig Dis Sci. 2012 Feb;57(2):440-50
ERMP1 protein, human
EC 3.4.-
*Peptide Hydrolases.
Oncogene. 2012 Jan 19;31(3):333-41.
TRY-
5 protein, C elegans
EC 3.4.-
*Peptide Hydrolases
*Caenorhabditis elegans Proteins
Seminal Plasma Proteins.
PLoS Genet. 2011 Nov;7(11):e1002375.
48-
kDa protease, Artocarpus heterophyllus
EC 3.4.-
*Peptide Hydrolases.
Eur Rev Med Pharmacol Sci. 2012 Jan;16(1):132-7
SepA protein, E coli
EC 3.4.-
*Peptide Hydrolases
*Escherichia coli Proteins
Virulence Factors.
J Infect Dis. 2012 Feb;205(3):431-44.
ROM4 protein, Toxoplasma gondii
EC 3.4.-
*Peptide Hydrolases
*Protozoan Proteins.
Med Sci (Paris). 2011 Jun-Jul;27(6-7):576-8
Aph1b protein, rat
EC 3.4.-
*Membrane Proteins
*Peptide Hydrolases.
Aph1a protein, rat
EC 3.4.-
*Membrane Proteins
*Peptide Hydrolases.
Arxes2 protein, mouse
EC 3.4.-
*Peptide Hydrolases.
Nucleic Acids Res 2011 Apr;39(8):3224-39
Arxes1 protein, mouse
EC 3.4.-
*Peptide Hydrolases.
Nucleic Acids Res 2011 Apr;39(8):3224-39
Losac protein, Lonomia obliqua
EC 3.4.-
*Peptide Hydrolases
*Insect Proteins
Factor X/agonists.
J Biol Chem 2011 Mar 4;286(9):6918-28
FSAP protein, rat
0
*Peptide Hydrolases.
Int J Mol Med 2010 Oct;26(4):549-55
SENP6 protein, rat
EC 3.4.-
*Peptide Hydrolases.
J Androl 2010 Jul-Aug;31(4):406-18
SLC7A6OS protein, human
0
*Peptide Hydrolases.
BMB Rep 2010 May;43(5):375-81
eumiliin, Euphorbia milii
EC 3.4.-
*Peptide Hydrolases.
Phytochemistry. 2010 May;71(7):708-15
CRBN protein, zebrafish
EC 3.4.-
*Peptide Hydrolases
*Zebrafish Proteins.
Science. 2010 Mar 12;327(5971):1345-50
SPC1 protein, S cerevisiae
0
*Peptide Hydrolases
*Saccharomyces cerevisiae Proteins.
SpyCEP protein, Streptococcus pyogenes
EC 3.4.-
*Peptide Hydrolases.
J Infect Dis 2005 Sep 1;192(5):783-90
ClpX protein, Campylobacter jejuni
EC 3.4.-
*Peptide Hydrolases.
Appl Environ Microbiol 2007 Dec;73(24):7803-13
ClpA protein, Campylobacter jejuni
EC 3.4.-
*Peptide Hydrolases.
Appl Environ Microbiol 2007 Dec;73(24):7803-13
DUG2 protein, S cerevisiae
EC 3.4.-
*Peptide Hydrolases
*Saccharomyces cerevisiae Proteins.
Genetics 2007 Mar;175(3):1137-51
CSN4 protein, Drosophila
EC 3.4.-
*Peptide Hydrolases.
Mol Biol Cell 2007 Apr;18(4):1179-86
Avizyme 1502
0
*Amylases
*Peptide Hydrolases
*Endo-1,4-beta Xylanases
Dietary Supplements.
Poult Sci. 2007 Mar;86(3)
Gcp glycoprotease, Staphylococcus aureus
EC 3.4.-
*Peptide Hydrolases.
FEMS Microbiol Lett 2005 Apr 15;245(2):279-85
ALTU-
135
EC 3.-
*Amylases
*Lipase
*Peptide Hydrolases.
J Pediatr 2006 Nov;149(5):658-662
ROM4 protein, Plasmodium falciparum
EC 3.4.-
*Peptide Hydrolases
*Protozoan Proteins.
J Cell Biol 2006 Sep 25;174(7):1023-33
PrtV protein, Vibrio cholerae
EC 3.4.-
*Peptide Hydrolases.
Proc Natl Acad Sci U S A 2006 Jun 13;103(24):9280-5
Senp5 protein, human
EC 3.4.-
*Peptide Hydrolases.
J Biol Chem 2006 Jun 9;281(23):15869-77
presequence protease PreP, Arabidopsis
EC 3.4.-
*Peptide Hydrolases
*Arabidopsis Proteins.
EMBO J 2006 May 3;25(9):1977-86
tropolysin, Trypanosoma
EC 3.4.-
*Peptide Hydrolases
*Protozoan Proteins.
Biochemistry 2005 Nov 8;44(44):14658-69
microfilarial protease, Brugia malayi
EC 3.4.-
*Peptide Hydrolases.
Indian J Exp Biol 2005 Sep;43(9):759-68
AVP protein, Human adenovirus type 2
EC 3.4.-
*Peptide Hydrolases
Viral Proteins.
Biochemistry 2005 Jun 21;44(24):8721-9
CRBN protein, human
EC 3.4.-
*Peptide Hydrolases.
Neurology 2004 Nov 23;63(10):1927-31
PrePII protein, Arabidopsis
EC 3.4.-
*Peptide Hydrolases
*Arabidopsis Proteins.
J Mol Biol 2005 Jun 17;349(4):847-60
PrePI protein, Arabidopsis
EC 3.4.-
*Peptide Hydrolases
*Arabidopsis Proteins.
J Mol Biol 2005 Jun 17;349(4):847-60
CSN5 protein, Drosophila
EC 3.4.-.-
*Peptide Hydrolases
*Intracellular Signaling Peptides and Proteins.
Cops5 protein, mouse
EC 3.4.-.-
*Peptide Hydrolases
*Intracellular Signaling Peptides and Proteins.
COPS5 protein, human
EC 3.4.-.-
*Peptide Hydrolases
*Intracellular Signaling Peptides and Proteins.
ompT protein, E coli
0
*Bacterial Outer Membrane Proteins
*Peptide Hydrolases
*Escherichia coli Proteins.
Senp3 protein, mouse
EC 3.4.
*Peptide Hydrolases.
Stambpl1 protein, mouse
EC 3.4.19.-
*Peptide Hydrolases.
Biochem Biophys Res Commun 2003 Sep 12;309(1):135-42
APH1B protein, human
EC 3.4.-
*Membrane Proteins
*Peptide Hydrolases.
Biochem Biophys Res Commun. 2003 Jun 6;305(3):502-9
APH1A protein, human
EC 3.4.-
*Membrane Proteins
*Peptide Hydrolases.
Biochem Biophys Res Commun. 2003 Jun 6;305(3):502-9
polyglutamyl gamma-
hydrolase
EC 3.4.-
*Peptide Hydrolases.
Biomacromolecules 2000 Spring;1(1):75-83
factor V activating enzyme
EC 3.4.-
*Peptide Hydrolases
Coagulants
Viper Venoms.
Biochem Biophys Res Commun 1999 Aug 27;262(2):328-32
cyanophycinase
EC 3.4.-
*Peptide Hydrolases.
Eur J Biochem 1999 Jul;263(1):163-9
DEVDase
EC 3.4.99.-
*Peptide Hydrolases
Caspase 3.
Oncogene 1997 Sep 25;15(13):1573-81
catalytin
0
*Quaternary Ammonium Compounds
*Amylases
*Peptide Hydrolases
Enzymes, Immobilized.
Antibio Khimioter 1997;42(3):11-4
SOM1 protein, S cerevisiae
0
*Peptide Hydrolases
*Mitochondrial Proteins
*Saccharomyces cerevisiae Proteins.
Mol Gen Genet 1996 Sep 25;252(4):437-45
peptidase L1
EC 3.4.99.-
*Peptide Hydrolases.
Biokhimiia 1996 Apr;61(4):656-63
PepB oligopeptidase, Streptococcus
EC 3.4.-
*Bacterial Proteins
*Peptide Hydrolases.
Infect Immun 1996 Aug;64(8):3401-6
protease I, Pyrococcus furiosus
EC 3.4.-
*Peptide Hydrolases
*Recombinant Fusion Proteins
*Archaeal Proteins
Archaeal Proteins.
J Bacteriol 1996 May;178(9):2605-12
pfaP protein, Leptospira borgpetersenii
EC 3.4.21.-
*Bacterial Proteins
*Peptide Hydrolases.
Gene 1995 Jul 4;160(1):133-4
COP9 signalosome complex
0
*Peptide Hydrolases
*Multiprotein Complexes.
Cell 1994 Jul 15;78(1):117-24
p80 protein, bovine viral diarrhea virus
156532-58-0
*Peptide Hydrolases
*Viral Nonstructural Proteins
*RNA Helicases.
J Virol 1994 May;68(5):3289-97
Persil
0
Lipids
*Peptide Hydrolases
*Polyphosphates
Surface-Active Agents.
Int Endod J 1993 Nov;26(6):334-43
somilase
EC 3.-
*Amylases
*Peptide Hydrolases.
Eksp Klin Farmakol 1992 May-Jun;55(3):24-6
teralgim
0
*Alginates
*Amylases
*Peptide Hydrolases
Drug Combinations.
Stomatologiia (Mosk) 1991 Sep-Oct;(5):46-7
immozymase
EC 3.4.99.-
*Peptide Hydrolases
Enzymes, Immobilized.
Probl Tuberk 1991;(6):42-5
SpoIIGA protein, Bacillus subtilis
EC 3.4.23.-
*Bacterial Proteins
*Membrane Proteins
*Peptide Hydrolases.
J Bacteriol 1991;173(24):7821
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