encyclopedia of medical concepts
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RNA Helicases

More information in Books or onNLM PubMed
Definition: A family of proteins that promote unwinding of RNA during splicing and translation. EC 2.7.7.-.     
Examples DEAD-box RNA Helicases; Eukaryotic Initiation Factor-4A
Other names Helicases, RNA; Helicase, RNA; RNA Helicase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
URH49 protein, mouse  EC 2.7.7.-   *RNA Helicases. J Biol Chem. 2011 Oct 7;286(40):34743-51.
HELZ protein, mouse  EC 2.7.7.-   *RNA Helicases. Nat Cell Biol 2004 Aug;6(8):731-40
HELZ protein, human  EC 2.7.7.-   *RNA Helicases. Nat Cell Biol 2004 Aug;6(8):731-40
DHX34 protein, human  EC 2.7.7.-   *RNA Helicases. Nucleic Acids Res 2011 May;39(9):3686-94
DHX34 protein, zebrafish  EC 2.7.7.-   *RNA Helicases *Zebrafish Proteins. Nucleic Acids Res 2011 May;39(9):3686-94
Bel protein, Drosophila  EC 2.7.7.-.   *RNA Helicases *Drosophila Proteins. Development. 2011 May;138(9):1737-45
DHX30 protein, human  EC 2.7.7.-   *RNA Helicases. Protein Cell 2010 Oct;1(10):956-64
RIG-I protein, rat  EC 2.7.7.-   *RNA Helicases. Neoplasia 2010 Nov;12(11):906-14
DHX16 protein, human  EC 2.7.7.-   *RNA Helicases. J Biol Chem 2010 Nov 12;285(46):35624-32
1-N,4-N-bis(4-(1H-benzimidazol-2-yl)phenyl)benzene-1,4-dicarboxamide  0   *Benzimidazoles RNA Helicases/antagonists & inhibitors. Biochemistry. 2010 Mar 9;49(9):1822-32
LGP2 protein, mouse  EC 2.7.7.-   *RNA Helicases. Proc Natl Acad Sci U S A 2010 Jan 26;107(4):1512-7
sen1 protein, S pombe  EC 3.6.1.-   *DNA Helicases *RNA Helicases.
SEN1 protein, S cerevisiae  EC 3.6.1.-   *DNA Helicases *RNA Helicases *Saccharomyces cerevisiae Proteins.
Dbp4 protein, human  EC 2.7.7.-   *RNA Helicases. Mol Cell Biol 2009 Jun;29(11):3007-17
Prp43 protein, human  EC 2.7.7.-   *RNA Helicases. Nucleic Acids Res 2009 Feb;37(3):891-902
DHX29 protein, human  EC 2.7.7.-   *RNA Helicases. Cell 2008 Dec 26;135(7):1237-50
DDX3 protein, Drosophila  EC 2.7.7.-   *RNA Helicases *Drosophila Proteins. Nucleic Acids Res 2008 Aug;36(14):4708-18
Mov10 protein, human  EC 2.7.7.-   *RNA Helicases. Nat Struct Mol Biol 2008 Jul;15(7):714-21
INCREASED SIZE EXCLUSION LIMIT2 protein, Arabidopsis  EC 2.7.7.-   *RNA Helicases *Arabidopsis Proteins. Plant Cell 2007 Jun;19(6):1885-97
DHX58 protein, human  EC 2.7.7.-   *RNA Helicases. J Immunol 2005 Oct 15;175(8):5260-8
DICER-1 protein, Drosophila  EC 2.7.7.-   *RNA Helicases *Drosophila Proteins *Ribonuclease III. Curr Biol 2006 Oct 10;16(19):1884-94
Ddx3x protein, mouse  EC 2.7.7.-   *RNA Helicases. Biochem J 1995 Jun 15;308(Pt 3):839-46
Upf1 protein, S pombe  EC 2.7.7.-   *RNA Helicases *Schizosaccharomyces pombe Proteins. Mol Cell Biol 2006 Sep;26(17):6347-56
UPF1 protein, Arabidopsis  EC 2.7.7.-   *RNA Helicases *Arabidopsis Proteins. Plant Cell Physiol 2006 May;47(5):572-80
SKIV2L2 protein, human  EC 3.6.1.-   *RNA Helicases. Biochem Biophys Res Commun 2006 Aug 4;346(3):1075-82
sum3 protein, S pombe  EC 2.7.7.-.   *Cell Cycle Proteins *Schizosaccharomyces pombe Proteins *DEAD-box RNA Helicases RNA Helicases.
SETX protein, human  EC 3.6.1.-   *RNA Helicases. Nat Genet 2004 Mar;36(3):225-7
armi protein, Drosophila  EC 2.7.7.-   *RNA Helicases *Drosophila Proteins. Cell 2004 Mar 19;116(6):817-29
DCR-2 protein, Drosophila  EC 2.7.7.-   *RNA Helicases *Drosophila Proteins *Ribonuclease III. Science 2003 Sep 26;301(5641):1921-5
Mov10l1 protein, mouse  EC 3.6.1.-   *RNA Helicases. Dev Biol. 2001 Jun 15;234(2):497-509; J Biol Chem 2003 Aug 1;278(31):28750-7; Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2043-8
TGBp1 protein, Poa semilatent virus  EC 2.7.7.-   *Viral Proteins *RNA Helicases Adenosine Triphosphatases. Virology 2002 May 10;296(2):321-9
SDE3 protein, Arabidopsis  EC 2.7.7.-   *RNA Helicases *Arabidopsis Proteins Gene Silencing. EMBO J 2001 Apr 17;20(8):2069-78
BRIP1 protein, human  EC 3.6.1.-   *DNA-Binding Proteins *RNA Helicases. Cell 2001 Apr 6;105(1):149-60
p66HEL protein, Human coronavirus 229E  EC 2.7.7.-   *DNA Helicases *Viral Proteins *RNA Helicases. RNA 2000 Jul;6(7):1056-68
2C helicase  EC 2.7.7.-   *Viral Proteins *RNA Helicases. Exp Mol Med 1998 Jun 30;30(2):101-7
degradosome  0   *Endoribonucleases *Multienzyme Complexes *Polyribonucleotide Nucleotidyltransferase *RNA Helicases. Proc Natl Acad Sci U S A 1998 Mar 17;95(6):3157-61
protein CI, plum pox potyvirus  EC 2.7.7.-   *Viral Proteins *RNA Helicases. Nucleic Acids Res 1997 Nov 15; 25(22):4474-80
Hel25E protein, Drosophila  EC 2.7.7.-   *RNA Helicases *Drosophila Proteins. Genetics 1997 Jul;146(3):951-63
BRR2 protein, S cerevisiae  EC 3.6.1.-   *RNA Helicases *Saccharomyces cerevisiae Proteins. Mol Biol Cell 1996 Oct;7(10):1601-21
p80 protein, bovine viral diarrhea virus  156532-58-0   *Peptide Hydrolases *Viral Nonstructural Proteins *RNA Helicases. J Virol 1994 May;68(5):3289-97
DB10 protein, Nicotiana sylvestris  0   *Plant Proteins *RNA Helicases. Plant Mol Biol 1994 Jan;24(1):249-52
NS3 protein, hepatitis C virus  0   *Viral Nonstructural Proteins Adenosine Triphosphatases Serine Endopeptidases Hepacivirus RNA Helicases. Chin Med J (Engl) 1993 Jul;106(7):522-6
nsP2 proteinase  EC 3.4.22.-   *Cysteine Endopeptidases RNA Helicases. Virology 1992 Dec;191(2):932-40
PRP16 protein, S cerevisiae  EC 3.6.1.-   *Adenosine Triphosphatases *RNA Helicases *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1992 Aug;12(6):3540-7
NAM7 protein, S cerevisiae  EC 3.6.1.-   *RNA Helicases *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1992 May;12(5):2165-77
NS3 protein, flavivirus  0   *Viral Nonstructural Proteins Serine Endopeptidases RNA Helicases Antigens, Viral. Nucleic Acids Res 1989;17(10):3889
RNA-dependent ATPase  EC 3.6.1.-   *Adenosine Triphosphatases RNA Helicases Saccharomyces cerevisiae Proteins. J Biol Chem 1980;255(24):11704

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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