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Serine Proteases

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Definition: Peptide hydrolases that contain at the active site a SERINE residue involved in catalysis.  do not confuse with SERINE ENDOPEPTIDASES   
Examples Cathepsin A; Dipeptidyl Peptidase 4; Serine Endopeptidases; Serine-Type D-Ala-D-Ala Carboxypeptidase
Other names Proteinases, Serine; Proteinase, Serine; Protein Hydrolases, Serine; Proteases, Serine; Protease, Serine; Serine Proteinase; Serine Protein Hydrolases; Serine Protease; Serine Proteinases
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
cordysobin protein, Cordyceps sobolifera  EC 3.4.-   *Fungal Proteins *Serine Proteases Reverse Transcriptase Inhibitors HIV Reverse Transcriptase. J Biosci Bioeng. 2012 Jan;113(1):42-7.
PsLon protein, human  EC 3.4.-   *Serine Proteases. J Biol Chem. 2011 Dec 30;286(52):44367-79.
Tysnd1 protein, human  EC 3.4.-   *Serine Proteases. J Biol Chem. 2011 Dec 30;286(52):44367-79.
ABHD11 protein, human  EC 3.4.-   *Serine Proteases. J Proteomics. 2011 Sep 6;74(10):1884-94
TMPRSS11A protein, mouse  EC 3.4.-   *Membrane Proteins *Serine Proteases. PLoS One. 2011;6(8):e23261.
Pic protein, Shigella flexneri  EC 3.4.-   *Bacterial Proteins *Serine Proteases Virulence Factors. Infect Immun 1999 Nov;67(11):5587-96
Tmprss3 protein, mouse  EC 3.4.-   *Membrane Proteins *Serine Proteases. J Biol Chem 2011 May 13;286(19):17383-97
PRSS56 protein, human  EC 3.4.-   *Serine Proteases. Am J Hum Genet 2011 Mar 11;88(3):382-90
rhinocerase protein, Bitis gabonica rhinoceros  EC 3.4.-   *Viper Venoms *Serine Proteases. PLoS One 2010;5(3):e9687
PRSS35 protein, human  EC 3.4.-   *Serine Proteases. J Dent Res 2010 Sep;89(9):927-32
Api m 7 allergen, Apis mellifera  EC 3.4.-   *Allergens *Serine Proteases Bee Venoms. Mol Biosyst 2010 Jun 18;6(6):1056-60
scarface protein, Drosophila  EC 3.4.-   *Drosophila Proteins *Serine Proteases. EMBO Rep 2010 May;11(5):373-9
bhalternin protein, Bothrops alternatus  EC 3.4.-   *Viper Venoms *Serine Proteases. Toxicon 2010 Jun 15;55(7):1365-77
Ssy5 protein, S cerevisiae  EC 3.4.-   *Saccharomyces cerevisiae Proteins *Serine Proteases. Mol Cell Biol 2010 Jul;30-(13):3299-309
RHBDL2 protein, human  EC 3.4.21.105   *Serine Proteases. J Mol Biol 2009 Dec 18;394(5):815-25
SBT5.4 protein, Arabidopsis  EC 3.4.21.-   *Arabidopsis Proteins *Serine Proteases. Planta 2009 Sep;230(4):687-97
PAMR1 protein, human  EC 3.4.24.-   *Serine Proteases. Am J Pathol. 2004 May;164(5):1773-82
ECRG-1 protein, human  0   *Membrane Proteins *Serine Proteases. Zhonghua Zhong Liu Za Zhi 2000 May;22(3):198-200; Zhonghua Zhong Liu Za Zhi. 1998 Jul;20(4):254-7
limulus factor D, Tachypleus tridentatus  EC 3.4.-   *Glycoproteins *Serine Proteases *Arthropod Proteins. FEBS Lett 1996 Dec 2;398(2-3):146-50
tripeptidyl-peptidase 1  EC 3.4.14.9   *Aminopeptidases *Dipeptidyl-Peptidases and Tripeptidyl-Peptidases *Serine Proteases Neuronal Ceroid-Lipofuscinoses Biological Markers. Arch Biochem Biophys 1993 Nov 1;306(2):354-9

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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