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Pentamidine

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Definition: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.     
Pharmacological Action Antifungal Agents; Antiprotozoal Agents; Trypanocidal Agents 		Other names Pentamidine Isethionate; Sicor Brand of Pentamidine Isethionate; Rh+¦ne-Poulenc Rorer Brand of Pentamidine Isethion; Pentamidine Mesylate; Pentamidin; Pentam; Pentacarinat; Lomidine; JHC Brand of Pentamidine Isethionate; NebuPent; GlaxoSmithKline Brand of Pentamidine Isethionate; Diamidine; Aventis Brand of Pentamidine Isethionate; American Pharmaceutical Partners Brand 2 of Pentam; American Pharmaceutical Partners Brand 1 of PentamDrugs* : PENTACARINAT; PENTAMIDINE ISETHIONATE; NEBUPENT; PENTAM
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
bis-benzimidazole diamidine  0   *Benzimidazoles Pentamidine/*analogs & derivatives. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3374-7
cis-platinum pentamidine thiocyanate  0   *Organoplatinum Compounds Pentamidine/*analogs & derivatives. J Chemother 2001 Feb;13(1):59-65
cis-platinum pentamidine seleniocyanate  0   *Organoplatinum Compounds Pentamidine/*analogs & derivatives. J Chemother 2001 Feb;13(1):59-65
cis-platinum pentamidine bromide  0   *Organoplatinum Compounds Pentamidine/*analogs & derivatives. J Chemother 2001 Feb;13(1):59-65
methoxypentamidine isethionate  0   Pentamidine/*analogs & derivatives. J Antimicrob Chemother 1996 Jul;38(1):145-50
butenamidine  0   Pentamidine/*analogs & derivatives. J Pharm Sci 1995 Apr;84(4): 448-55
gamma-oxapentamidine  0   Pentamidine/*analogs & derivatives. Eur J Biochem 1994 Dec 15;226(3):953-61
N,N'-dihydroxypentamidine  101689-95-6   Pentamidine/*analogs & derivatives. Antimicrob Agents Chemother 1990;34(9):1678
N-hydroxypentamidine  130349-07-4   Pentamidine/*analogs & derivatives. Antimicrob Agents Chemother 1990;34(9):1678
1,3-di-(4-imidazolino-2-methoxyphenoxy)propane  109444-03-3   Pentamidine/*analogs & derivatives Pneumonia, Pneumocystis/drug therapy. Antimicrob Agents Chemother 1990;34(6):1026
1,3-di(4-imidazolinophenoxyl)propane  129073-92-3   Pentamidine/*analogs & derivatives Pneumonia, Pneumocystis/drug therapy. Antimicrob Agents Chemother 1990;34(6):1026
butamidine  121324-49-0   Pentamidine/*analogs & derivatives. J Med Chem 1990;33(4):1252
platinum(II) pentamidine  101299-67-6   *Organoplatinum Compounds Pentamidine/*analogs & derivatives. Bull Soc Pathol Exot Filiales 1988;81(3 Pt 2):626

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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