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Phenylglyoxal

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Definition: A reagent that is highly selective for the modification of arginyl residues. It is used to selectively inhibit various enzymes and acts as an energy transfer inhibitor in photophosphorylation.     
Pharmacological Action Enzyme Inhibitors; Indicators and Reagents
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4,4'-dihydroxybenzil  0   Phenylglyoxal/*analogs & derivatives. Angew Chem Int Ed Engl 2009;48(42):7783-6
4-(3-methyl-2-butenoxy)isonitrosoacetophenone  0   Phenylglyoxal/*analogs & derivatives. Phytochemistry 1999 Mar;50(6):983-9
3-methoxyphenylglyoxal  32025-65-3   Phenylglyoxal/*analogs & derivatives. Biochim Biophys Acta 1992 Sep 21;1110(1):75-80
4-methoxyphenylglyoxal  1076-95-5   Phenylglyoxal/*analogs & derivatives. Biochim Biophys Acta 1992 Sep 21;1110(1):75-80
4,4'-dimethylbenzil  3457-48-5   Phenylglyoxal/*analogs & derivatives. J Biolumin Chemilumin 1992 Jan;7(1):27-35
4,4'-dimethoxybenzil  1226-42-2   Phenylglyoxal/*analogs & derivatives. J Biolumin Chemilumin 1992 Jan;7(1):27-35
fluorescein isothiocyanate-phenylglyoxal  116843-39-1   Phenylglyoxal/*analogs & derivatives Fluorescein-5-isothiocyanate/*analogs & derivatives. Am J Physiol 1989;256(4 Pt 1):G645
isonitrosoacetophenone  532-54-7   Phenylglyoxal/*analogs & derivatives. J Neurochem 1988;51(4):1097
4-sulfonylphenylglyoxal  67014-03-3 Benzenesulfonic acid, 4-(oxoacetyl)  Phenylglyoxal/*analogs & derivatives. Thromb Haemost 1983;49(3):176
4-azidophenylglyoxal  65322-07-8 Benzeneacetaldehyde, 4-azido-alpha-oxo  *Azides Phenylglyoxal/*analogs & derivatives. Biochemistry 1981;20(2):372; J Biol Chem 1981:21;11313
4-carboxyphenylglyoxal  20099-54-1 Benzoic acid, 4-(oxoacetyl)  Phenylglyoxal/*analogs & derivatives. Eur J Biochem 1981;116(3):505
4-nitrophenylglyoxal  4974-57-6   Phenylglyoxal/*analogs & derivatives. Anal Biochem 1981;111(2):220
4-hydroxyphenylglyoxal  24645-80-5   Phenylglyoxal/*analogs & derivatives. Anal Biochem 1980;109(1):32
4-hydroxy-3-nitrophenylglyoxal  71222-21-4 Benzeneacetaldehyde, 4-hydroxy-3-nitro-alpha-oxo  Phenylglyoxal/*analogs & derivatives. Biochem Biophys Res Commun 1980;96(3):1071
diphenylglyoxal bis(2-hydroxybenzoyl hydrazone)  73319-79-6 Benzoic acid, 2-hydroxy-, 2,2'-(1,2-diphenyl-1,2-ethanediylidene)dihydrazide  Phenylglyoxal/*analogs & derivatives. Analyst 1980;105(1248):193
Rec-15/0209  24518-45-4 N,p-dichloroacetylanilinoethoxy-4-nitrophenylglyoxal diacetal  Phenylglyoxal/*analogs & derivatives.
1,4-phenyldiglyoxal  2673-16-7 1,4-Benzenediacetaldehyde, alpha,alpha'-dioxo  Phenylglyoxal/*analogs & derivatives. Nucleic Acids Res 5(11):4065;1978
benzil  134-81-6   Phenylglyoxal/*analogs & derivatives. Arch Farmacol Toxicol 3(3):231;1977; Cancer Chemotherapy Reports 4(2):261;1973; J Am Chem Soc 99(25):8332;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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