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Phosphatidate Phosphatase

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Definition: A phosphomonoesterase involved in the synthesis of triacylglycerols. It catalyzes the hydrolysis of phosphatidates with the formation of diacylglycerols and orthophosphate. EC 3.1.3.4.      Other names Phosphatidate Phosphohydrolase; Phosphohydrolase, Phosphatidic Acid; Phosphohydrolase, Phosphatidate; Phosphatase, Phosphatidic Acid; Phosphatase, Phosphatidate; Phosphatidic Acid Phosphohydrolase; Phosphatidic Acid Phosphatase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Lipin 2 protein, mouse  EC 3.1.3.4.   *Phosphatidate Phosphatase. J Biol Chem 2009 Mar 13;284(11):6763-72
DPPL2 protein, human  EC 3.1.3.4   *Phosphatidate Phosphatase. Gene 2007 Sep 15;399(2):174-80
DPPL1 protein, human  EC 3.1.3.4   *Phosphatidate Phosphatase. Gene 2007 Sep 15;399(2):174-80
LPP3 protein, human  EC 3.1.3.4   *Phosphatidate Phosphatase. FEBS Lett 2007 Jun 26;581(16):3063-8
PAP2d protein, human  EC 3.1.3.4   *Phosphatidate Phosphatase. Mol Cell Biochem 2005 Apr;272(1-2):91-6
Wun2 protein, Drosophila  EC 3.1.3.4   *Phosphatidate Phosphatase *Drosophila Proteins. Science 2004 Sep 24;305(5692):1963-6
LPIN1 protein, human  EC 3.1.3.4   *Phosphatidate Phosphatase Membrane Proteins Nuclear Proteins.
LPP3 protein, mouse  EC 3.1.3.4   *Phosphatidate Phosphatase. Development 2003 Oct;130(19):4623-37
Lpin1 protein, mouse  EC 3.1.3.4   *Nuclear Proteins *Phosphatidate Phosphatase. Genomics 1999 Dec 15;62(3):436-44; Nat Genet 201 Jan;27(1):121-4
phosphatidic acid phosphatase type 2  EC 3.1.3.-   *Phosphatidate Phosphatase. Genomics 2000 Jan 1;63(1):142-4
lipid phosphate phosphatase  EC 3.1.3.-   *Phosphatidate Phosphatase Arabidopsis Proteins Saccharomyces cerevisiae Proteins. J Biol Chem 1998 Jun 5;273(23):14331-8
wunen protein, Drosophila  EC 3.1.3.4   *Membrane Proteins *Phosphatidate Phosphatase *Drosophila Proteins. Nature 1997 Jan 2;385(6611):64-7
SMP2 protein, S cerevisiae  EC 3.1.3.4   *Phosphatidate Phosphatase *Saccharomyces cerevisiae Proteins Saccharomyces cerevisiae. Mol Gen Genet 1993 Jan;236(2-3):283-8

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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