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Plasma Substitutes

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Definition: Any liquid used to replace blood plasma, usually a saline solution, often with serum albumins, dextrans or other preparations. These substances do not enhance the oxygen- carrying capacity of blood, but merely replace the volume. They are also used to treat dehydration.  BLOOD SUBSTITUTES is also available    Other names Plasma Volume Expanders; Blood Expanders; Volume Expanders, Plasma; Substitutes, Plasma; Expanders, Plasma Volume; Expanders, Blood
Substances having this pharmacologic action: plasma protein fraction; Polygeline; Povidone; Hetastarch; Dextrans
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
protesalin  136511-35-8   Proteins Sodium Chloride Plasma Substitutes. Fiziol Zh 1991;37(1):42
polystarch  0   *Starch Plasma Substitutes. Lancet 1990;335(8683):233
succinylated gelatin  39340-57-3   *Gelatin *Succinates Plasma Substitutes. Anaesthesia 1989;44(5):392
adenosine triphosphate-stroma-free hemoglobin  0   *Hemoglobins Adenosine Triphosphate/*analogs & derivatives Plasma Substitutes. Arch Surg 1987;122(3):355
SAG-M blood  0   *Erythrocytes Plasma Substitutes. Anaesthesia 1986;41(11):1163
Plasmalyte A  97397-05-2   *Electrolytes Plasma Substitutes. J Trauma 1986;26(2):168
Plasmalyte R  97397-06-3   *Electrolytes Plasma Substitutes. J Trauma 1986;26(2):168
alpha,beta poly((2-hydroxyethyl)aspartamide)tyramine  0   *Peptides Plasma Substitutes. Biomaterials 1985;6(3):203
hemoce  110120-01-9   *Gelatin Plasma Substitutes. Rev Esp Anestesiol Reanim 1984;31(4):173
physiogel  9049-67-6   *Gelatin Plasma Substitutes. Vox Sang 1984;47(1):41
hyperoncotic albumin  0   *Albumins Plasma Substitutes. J Trauma 1981;21(1):63
stable plasma protein solution  0   *Blood Proteins Plasma Substitutes. Anaesth Intensive Care 1980;8(4):474
poly-N(5)-(2-hydroxyethyl)glutamine  27878-59-7   *Peptides Plasma Substitutes. Farmaco (Prat) 1980;35(11):575
modified fluid gelatins  0   *Gelatin Plasma Substitutes. Acta Physiol Pol 1980;31(2):201
plasmagel  39290-10-3   *Gelatin Plasma Substitutes. Acta Physiol Pol 1980;31(2):201
rheogluman  0   *Dextrans *Mannitol Drug Combinations Plasma Substitutes. Klin Khir 1980;(3):4
hexamethylene diisocyanate cross-linked polypeptides  0   *Cyanates *Peptides Plasma Substitutes. Eur J Clin Pharmacol 14(6):405;1978
hydroxyethylamylopectin  56448-79-4 Amylopectin, 2-hydroxyethyl ether  Amylopectin/*analogs & derivatives Plasma Substitutes. Br J Haematol 40(2):231;1978; J Lab Clin Med 1979;94(6):841
normosol R  68073-09-6 normosol R-pH 7.4  *Isotonic Solutions Plasma Substitutes. Anesthesiology 49(2):99;1978
Fluosol-DA  75216-20-5 Fluosol DA  *Fluorocarbons Drug Combinations Blood Substitutes Plasma Substitutes.
Pharma Action Contrast Media ; Radiation-Sensitizing Agents
JAMA 1980;243(8):719; JAMA 1980;243(8):721; Jpn J Anesthesiol 27(7):717;1978; Kokyu To Junkan 1979;27(8):869; Masui 1979;28(9):929
hemoglobin, stroma free  0   *Hemoglobins Blood Substitutes Plasma Substitutes. Am J Surg 135(5):656;1978
Gelvisol  0   *Glutamates *Hexoses Drug Combinations Cholecystitis/drug therapy Palliative Care Plasma Substitutes Vitamins. Probl Gematol Pereliv Krovi 23(10):43;1978; Vest Khirur 120(3):114;1978
Gelatinol  39340-56-2   *Gelatin Plasma Substitutes. Probl Gematol Pereliv Krovi 21(4):56;1976
plasmion  54847-63-1   *Gelatin Plasma Substitutes. Anesth Analg (Paris) 33(1):37;1976
Duxon  40704-75-4   *Polymethacrylic Acids Plasma Substitutes. Cas Lek Cesk 114(41):1268;1975; J Biomed Mater Res 10:953;1976; Rev Czech Med 22(3):152;1976
polidez  0   *Polyvinyl Alcohol *Sodium Chloride Drug Combinations Plasma Substitutes. Khirurgiia (1):97;1979; Orthop Travmatol Protez 8:5;1977; Patol Fiziol Eksp Ter (5):37;1978; Probl Gematol Pereliv Krovi 22(7):40;1977; Vestn Khir 115(10):62;1975
Plasma, artificial FSB-FSP  0   Isotonic Solutions Plasma Substitutes. Eur J Toxicol 8(4):205;1975
alpha,beta-poly((2-hydroxyethyl)-aspartamide)  0   *Peptides Plasma Substitutes. Farmaco (Prat) 34(4):146;1979; J Med Chem 16(8):893;1973
perfluorodecalin  306-94-5   *Fluorocarbons Blood Substitutes Plasma Substitutes Vitreous Body. Adv Exp Med Biol 37B:687;1973; Jpn J Anesthesiol 25(3):293;1976; Pflugers Arch 376(1):1;1978; Verh Dtsch Ges Pathol 62:312;1978
hydrolysin  12798-06-0   *Protein Hydrolysates Plasma Substitutes. Probl Gematol Pereliv Krovi (Moskva) 17(7):29;1972
hemodes  53795-75-8   *Povidone Plasma Substitutes.
Pharma Action Adjuvants, Immunologic ; Anti-Inflammatory Agents, Non-Steroidal
Farmakol Toksikol 41(5):568;1978; Sud Med Ekspert 1979;22(4):53; Vestn Oftalmol 2:57;1973; Z Nevropatol Psychiatr 76(2):278;1976
aminokrovin  76773-71-2   Blood Proteins Plasma Substitutes. Kardiologiia 18(3):76;1978; Probl Gematol Pereliv Krovi 18(2):8;1973; Probl Gematol Pereliv Krovi 22(12):16;1977
oxypolygelatine  9005-91-8   *Gelatin Plasma Substitutes.
Pharma Action Contrast Media
Z Prakt Anaesth Wiederbeleb 7(5):283;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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