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Polychlorinated Biphenyls

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Definition: Industrial products consisting of a mixture of chlorinated biphenyl congeners and isomers. These compounds are highly lipophilic and tend to accumulate in fat stores of animals. Many of these compounds are considered toxic and potential environmental pollutants.  "yusho poisoning": see note on RICE   
Pharmacological Action Environmental Pollutants
Other names Polychlorobiphenyl Compounds; PCBs; Compounds, Polychlorobiphenyl; Biphenyls, Polychlorinated
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2,3,3'-trichlorobiphenyl  0   *Polychlorinated Biphenyls. Chem Commun (Camb). 2011 Apr 7;47(13):3808-10
2,3,4,4',5-pentachlorobiphenyl  0   *Polychlorinated Biphenyls. Bull Environ Contam Toxicol. 2010 Jan;84(1):66-70
2,4,4',5-tetrachlorobiphenyl  0   *Polychlorinated Biphenyls. Toxicol Appl Pharmacol 2009 Jun 1;237(2):237-45
2,2',3,3',4,4',5-heptachlorobiphenyl  0   *Polychlorinated Biphenyls. Toxicol Appl Pharmacol 2009 Jun 1;237(2):168-77
(2S)-3-(2',5'-dichlorobiphenyl-4-yl)-2-(((1-(2-methoxybenzoyl)piperidin-3-yl)carbonyl)amino)propanoic acid  0   *Polychlorinated Biphenyls. Eur J Pharmacol 2007 Mar 22;559(2-3):202-9
2,3,6,7-tetrachlorobiphenylene  0   *Polychlorinated Biphenyls. Toxicol In Vitro. 2006 Oct;20(7):1234-7
2,3,6-trichlorobiphenylene  0   *Polychlorinated Biphenyls. Toxicol In Vitro. 2006 Oct;20(7):1234-7
2,3-dichlorobiphenylene  0   *Polychlorinated Biphenyls. Toxicol In Vitro. 2006 Oct;20(7):1234-7
2,3,4,5-tetrachlorobiphenyl  0   *Polychlorinated Biphenyls. FEMS Microbiol Ecol 2006 Feb;55(2):248-61
clophen T 64  0   *Polychlorinated Biphenyls. J Environ Sci Health A Tox Hazard Subst Environ Eng 2005;40(9):1665-78
4-OH-2',3,3',4',5,5'-hexachlorrobiphenyl  0   *Polychlorinated Biphenyls. Brain Res Dev Brain Res 2005 Feb 8;154(2
4-OH-2',3,3',4',5'-pentachlorobiphenyl  0   *Polychlorinated Biphenyls. Brain Res Dev Brain Res 2005 Feb 8;154(2):259-63
2,2',4,4',5-pentachlorobiphenyl  0   *Polychlorinated Biphenyls. Reprod Toxicol 2004 Dec;19(2):169-80
4-amino-3,3'-dichloro-5,4'-dinitrobiphenyl  0   *Polychlorinated Biphenyls. Mutat Res 2004 May 9;560(1);33-40
KC 500  0   *Polychlorinated Biphenyls. Toxicol Sci 2003 Apr;72(2):235-41
2,2',4,6-tetrachlorobiphenyl  0   *Polychlorinated Biphenyls. Toxicol Appl Pharmacol 2002 Jan 1;178(1):37-43
2,4,5,2',3',4'-hexachlorobiphenyl  0   *Polychlorinated Biphenyls. Fukuoka Igaku Zasshi 2001 May;92(5)167-76
4-hydroxy-2',3',4'-5'-tetrachlorobiphenyl  67651-34-7   *Polychlorinated Biphenyls. Environ Toxicol Chem 2001 Feb;20(2):351-8
2,2',4,6,6'-pentachlorobiphenyl  0   *Polychlorinated Biphenyls. Toxicol Appl Pharmacol 2000 Nov 15;169(1):1-7
PCB 180  35065-29-3   *Polychlorinated Biphenyls. Pediatr Res 2000 May;47(5) 598-601
2,2',3,4',5',6-hexachlorobiphenyl  0   *Polychlorinated Biphenyls. Arch Environ Contam Toxicol 1999 Jul;37(1):135-42
2,2',6,6'-tetrachlorobiphenyl  0   *Polychlorinated Biphenyls. J Cell Biochem 1999 Jan 1;72(1):94-102
2,3,3',4',5-pentachloro-4-hydroxybiphenyl  0   *Polychlorinated Biphenyls. Xenobiotica 1998 Jan;28(1):21-30
2',3,3',4',5-pentachloro-4-hydroxybiphenyl  0   *Polychlorinated Biphenyls. Xenobiotica 1998 Jan;28(1):21-30
3,3',4',5-tetrachloro-4-hydroxybiphenyl  0   *Polychlorinated Biphenyls. Xenobiotica 1998 Jan;28(1):21-30
5,5'-bis-trifluoromethyl-2,2'-dichlorobiphenyl  0   *Polychlorinated Biphenyls. Toxicology 1997 Jul 11;120(3):197-205
4-hydroxy-2',4',6'-trichlorobiphenyl  0   *Polychlorinated Biphenyls. Biol Reprod 1997 Feb;56(2):341-7
2',3',4',5'-tetrachloro-4-biphenylol  0   *Polychlorinated Biphenyls. Toxicol Appl Pharmacol 1997 Jan;142(1):160-8
2,4,6-trichlorobiphenyl  35693-92-6   *Polychlorinated Biphenyls. Reprod Toxicol 1996 Jan-Feb;10(1):21-8
2,2',3,3',4,6'-hexachlorobiphenyl  38380-05-1   *Polychlorinated Biphenyls. Chemosphere 1995 Jun;30(11):2079-85
4'-trifluoromethyl-2,3,4,5-tetrachlorobiphenyl  88966-73-8   *Polychlorinated Biphenyls. J Biochem Toxicol 1994 Oct;9(5):241-8
2,5,3'-trichlorobiphenyl  38444-81-4   *Polychlorinated Biphenyls. J Bacteriol 1995 Jan;177(1):20-6
2,3'-dichlorobiphenyl  25569-80-6   *Polychlorinated Biphenyls. J Bacteriol 1995 Jan;177(1):20-6
2,3,3',4,4',5-hexachlorobiphenyl  38380-08-4   *Polychlorinated Biphenyls. Toxicol Appl Pharmacol 1994 Jun;126(2):202-13
2,4,4'-trichlorobiphenyl  7012-37-5   *Polychlorinated Biphenyls. Toxicol Lett 1993 Jun;68(3):311-23
2,2',5-trichlorobiphenyl  37680-65-2 1,1'-Biphenyl, 2,2',5-trichloro  *Polychlorinated Biphenyls. Bull Environ Contam Toxicol 1992 Dec;49(6):839-46
2,3,5,6-tetrachlorobiphenyl  33284-54-7   *Polychlorinated Biphenyls. FEMS Microbiol Lett 1992 Jul 15;73(3):247-50
Delor 106  71662-08-3   *Polychlorinated Biphenyls. Teratogenesis Carcinog Mutagen 1991;11(2):77-82
3-hydroxy-2,5,2',5'-tetrachlorobiphenyl  51274-67-0   *Polychlorinated Biphenyls. Fukuoka Igaku Zasshi 1991;82(5):191
2,3',4,4',5-pentachlorobiphenyl  31508-00-6   *Polychlorinated Biphenyls. Arch Environ Contam Toxicol 1991;20(3):349
2,2',3,3'-tetrachlorobiphenyl  38444-93-8   *Polychlorinated Biphenyls. Immunology 1991;72(2):287
2,3,3',4,4'-pentachlorobiphenyl  32598-14-4   *Polychlorinated Biphenyls. Pharmacol Toxicol 1990;67(4):344
4'-hydroxy-3,4,5,3',5'-pentachlorobiphenyl  130689-92-8   *Polychlorinated Biphenyls. J Pharmacobiodyn 1990;13(8):497
2,2',3,5,5',6-hexachlorobiphenyl  52663-63-5   *Polychlorinated Biphenyls. Biochim Biophys Acta 1990;1036(3):167
2,2',3,4'-tetrachlorobiphenyl  36559-22-5   *Polychlorinated Biphenyls. J Anal Toxicol 1990;14(3):143
5,5',6-trichlorobiphenyl  38444-84-7   *Polychlorinated Biphenyls. Bull Environ Contam Toxicol 1990;44(5):790
2,2',3,3',4,4',6,6'-octachlorobiphenyl  33091-17-7   *Polychlorinated Biphenyls. Biochem Pharmacol 1989;38(8):1345
2,2',3,4,4',6-hexachlorobiphenyl  56030-56-9   *Polychlorinated Biphenyls. Biochem Pharmacol 1989;38(8):1345
2,2',4,4',5-pentachlorodiphenyl ether  119036-18-9   *Ethers *Polychlorinated Biphenyls. Arch Toxicol 1988;62(4):258
2,3',4,4'-tetrachlorobiphenyl  32598-10-0 1,1'-Biphenyl, 2,3',4,4'-tetrachloro  *Polychlorinated Biphenyls. Environ Res 1987;44(2):213
3-methylsulfonyl-4,5,3',4'-tetrachlorobiphenyl  104104-34-9   *Polychlorinated Biphenyls Aryl Hydrocarbon Hydroxylases/antagonists & inhibitors. Fukuoka Igaku Zasshi 1987;78(5):199
Sovol  37353-77-8   *Polychlorinated Biphenyls. Eksp Onkol 1987;9(3):20
2,3,4',6-tetrachlorobiphenyl  52663-58-8   *Polychlorinated Biphenyls. Xenobiotica 1987;17(4):477
Fenclor 64  72841-24-8   *Polychlorinated Biphenyls. Vet Res Commun 1987;11(1):57
4-methylsulfonyl-2,2',5,5'-tetrachlorobiphenyl  60640-55-3   *Polychlorinated Biphenyls. Toxicol Lett 1986;32(3):261
4,4'-bis(ethylsulfonyl)-2,2',5,5'-tetrachlorobiphenyl  94659-41-3 1,1'-Biphenyl, 2,2',5,5'-tetrachloro-4,4'-bis(ethyl-2-14C-sulfonyl)-, (+-)  *Polychlorinated Biphenyls. Acta Pharmacol Toxicol (Copenh) 1984;55(5):429
4,4'-bis(methylsulfonyl)-2,2',5,5'-tetrachlorobiphenyl  66640-68-4   *Polychlorinated Biphenyls. Mol Pharmacol 1985;27(2):314
2,2',5,5'-tetrachlorobiphenyl 3,4-oxide  68099-35-4 7-Oxabicyclo(4.1.0)hepta-2,4-diene, 2,5-dichloro-3-(2,5-dichlorophenyl)  *Polychlorinated Biphenyls. Chem Biol Interact 1984;50(3):289
clophen A60  11096-99-4   *Polychlorinated Biphenyls. Toxicol Appl Pharmacol 1984;75(2):278
clophen A30  55600-34-5   *Polychlorinated Biphenyls. Toxicol Appl Pharmacol 1984;75(2):278
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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