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Pregnadienetriols

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Definition: Doubly unsaturated pregnane derivatives substituted with three hydroxy groups anywhere within the ring structure or side chains.     
Examples Beclomethasone; Betamethasone; Desonide; Dexamethasone; Flumethasone; Paramethasone; Prednisolone 		Other names Trihydroxypregnadienes
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
methyl 3,20-dioxo-9-fluoro-11,17,21-trihydroxy-1,4-pregnadiene-16-carboxylate  0   *Pregnadienetriols. Steroids 1997 Jun;62(6):491-99
flucloronide  3693-39-8   *Pregnadienetriols.
fluprednidene acetate  1255-35-2   *Pregnadienetriols.
Pharma Action Glucocorticoids
prednazoline  6693-90-9   *Imidazoles *Pregnadienetriols. J Radiol 1984;65(4):267
SQ 20589  749-69-9 21-chloro-11 beta,16 alpha,17 alpha-trihydroxypregna-1,4-diene-3,20-dione, 16,17-acetonide  *Pregnadienetriols. Curr Ther Res 16(7):748;1974; J Investig Dermatol 66(3):157;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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