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Protein-Arginine N-Methyltransferases

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Definition: Enzymes that catalyze the methylation of arginine residues of proteins to yield N-mono- and N,N-dimethylarginine. This enzyme is found in many organs, primarily brain and spleen.      Other names Protein-Arginine N-Methyltransferase; Protein Methyltransferase I; Protein Methylase I; Protein Arginine Methyltransferase; Protein Arginine N Methyltransferases; Protein Arginine N Methyltransferase; N-Methyltransferases, Protein-Arginine; N-Methyltransferase, Protein-Arginine; N-Methyltransferase, Histone-Arginine; Methyltransferase, Protein Arginine; Histone Arginine N Methyltransferase; Arginine Methyltransferase, Protein; Myelin Basic Protein (Arginine) Methyltransferase; Histone-Arginine N-Methyltransferase; Arginine Methylase; (Myelin Basic Protein)-Arginine N-Methyltransferas
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
NTMT protein, Drosophila  EC 2.1.1.-   *Protein-Arginine N-Methyltransferases *Drosophila Proteins. Nucleic Acids Res. 2012 Feb;40(4):1536-49.
ART8 protein, Drosophila  EC 2.1.1.-   *Protein-Arginine N-Methyltransferases *Drosophila Proteins. Nucleic Acids Res. 2012 Feb;40(4):1536-49.
PRMT7 protein, mouse  EC 2.1.1.125   *Protein-Arginine N-Methyltransferases. Exp Mol Med. 2011 Oct 31;43(10):550-60
PRMT5 protein, zebrafish  EC 2.1.1.-   *Protein-Arginine N-Methyltransferases *Zebrafish Proteins. PLoS One. 2011;6(10):e25427.
PRMT8 protein, mouse  EC 2.1.1.-   *Protein-Arginine N-Methyltransferases. Neuroscience 2009 Nov 10;163(4):1146-57
Prmt1 protein, mouse  EC 2.1.1.-   *Protein-Arginine N-Methyltransferases. Mol Cell Biol 2010 Jan;30(1):260-72
PRMT1 protein, rat  EC 2.1.1.-   *Protein-Arginine N-Methyltransferases. Life Sci 2009 Jul 17;85(3-4):161-6
PRMT5 protein, Arabidopsis  EC 2.1.1.23   *Protein-Arginine N-Methyltransferases *Arabidopsis Proteins. Plant Physiol 2007 Aug;144(4):1913-23
PRMT1 protein, Trypanosoma brucei  EC 2.1.1.-   *Protein-Arginine N-Methyltransferases Protozoan Proteins. RNA 2006 Aug;12(8):1545-55
PRMT8 protein, human  EC 2.1.1.23   *Membrane Proteins *Protein-Arginine N-Methyltransferases Nerve Tissue Proteins. J Biol Chem 2005 Sep 23;280(38):32890-6
protein arginine N-methyltransferase 3, mouse  EC 2.1.1.23   *Protein-Arginine N-Methyltransferases. Biochem J 2005 Feb 15;386(Pt 1):85-91
PRMT3 protein, S pombe  EC 2.1.1.-   *Protein-Arginine N-Methyltransferases *Schizosaccharomyces pombe Proteins. EMBO J 2004 Jul 7;23(13):2641-50
HSL7 protein, Xenopus  EC 2.7.1.-   *Protein-Arginine N-Methyltransferases *Xenopus Proteins. J Cell Biol 2004 Dec 6;167(5):841-9
PRMT7 protein, human  EC 2.1.1.125   *Protein-Arginine N-Methyltransferases. J Biol Chem 2004 May 28;279(22):22902-7
HMT1 protein, S cerevisiae  EC 2.1.1.-   *Protein-Arginine N-Methyltransferases *Repressor Proteins *Saccharomyces cerevisiae Proteins. RNA 2003 Jun;9(6):746-59
protein arginine methyltransferase 2  EC 2.1.1.23   *Protein-Arginine N-Methyltransferases. J Biol Chem 2002 Aug 9;277(32):28624-30
FBXO11 protein, human  EC 2.1.1.23   *Protein-Arginine N-Methyltransferases *F-Box Proteins Vitiligo. Pigment Cell Res 2001 Dec;14(6):475-84
PRMT6 protein, human  EC 2.1.1.-   *Nuclear Proteins *Protein-Arginine N-Methyltransferases. J Biol Chem 2002 Feb 1;277(5):3537-43
PRMT3 protein, human  EC 2.1.1.-   *Protein-Arginine N-Methyltransferases. EMBO J 2000 Jul 17;19(14):3509-19
HSL7 protein, S cerevisiae  EC 2.1.1.125   *Protein-Arginine N-Methyltransferases *Saccharomyces cerevisiae Proteins. Proc Natl Acad Sci USA 1999 Jul 20;96(15):8522-7
coactivator-associated arginine methyltransferase 1  EC 2.1.1.-   *Protein-Arginine N-Methyltransferases. Science 1999 Jun 25;284(5423):2174-7
RMT2 protein, S cerevisiae  EC 2.1.1.-   *Protein-Arginine N-Methyltransferases *Saccharomyces cerevisiae Proteins. J Biol Chem 1999 Jan 8;274(2):814-24
PRMT1 protein, human  EC 2.1.1.-   *Protein-Arginine N-Methyltransferases *Repressor Proteins. Gene 1996 May 24;171(1):107-11
PRMT2 protein, human  EC 2.1.1.-   *Protein-Arginine N-Methyltransferases *Intracellular Signaling Peptides and Proteins. EMBO J 1992 Oct;11(10):3491-9

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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