encyclopedia of medical concepts
ψ 

Quinacrine

More information in Books or onNLM PubMed
Definition: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.     
Pharmacological Action Anticestodal Agents; Antimalarials; Antinematodal Agents; Antineoplastic Agents; Enzyme Inhibitors
Examples Quinacrine Mustard 		Other names Mepacrine; Monomesylate, Quinacrine; Monohydrochloride, Quinacrine; Monoacetate, Quinacrine; Hydrochloride, Quinacrine; Dimesylate, Quinacrine; Dihydrochloride, Quinacrine; Quinacrine, (S)-Isomer; Quinacrine, (R)-Isomer; Quinacrine, (+-)-Isomer; Quinacrine Monomesylate; Quinacrine Monohydrochloride; Quinacrine Monoacetate; Quinacrine Hydrochloride; Quinacrine Dimesylate; Quinacrine Dihyrochloride, (S)-Isomer; Quinacrine Dihyrochloride, (R)-Isomer; Quinacrine Dihydrochloride, Dihydrate; Quinacrine Dihydrochloride; Atebrin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
aminobenzoic acid, calcium pantothenate, chloroquine, quinacrine, pyridoxine drug combination  0   *Chloroquine *4-Aminobenzoic Acid *Pantothenic Acid *Pyridoxine *Quinacrine Drug Combinations. Presse Med 1986;15(39):1974
quinacrine half mustard  68725-63-3   Quinacrine/*analogs & derivatives. Cancer Res 1981;41(10):3844
dimethylquinacrine  65370-56-1 Acridinium, 6-chloro-9-((4-(diethylmethylammonio)-1-methylbutyl)amino)-2-methoxy-10-methyl-, diiodide  Quinacrine/*analogs & derivatives. Biochemistry 17(20):4220;1978
Preparation ABP  78393-40-5 Imidodicarbonimidic diamide, N-(4-chlorophenyl)-N'-(1-methylethyl)-, mixt. with N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-1,4-pentanediamine dihydrochloride and N,N-diethyl-N'-(6-methoxy-8-quinolinyl)-1,3-propanediamine  *Aminoquinolines *Proguanil *Quinacrine Drug Combinations. Veterinariia 3:64;1975
ethosuximide, quinacrine drug combination  76270-09-2 2,5-Pyrrolidinedione, 3-ethyl-3-methyl-, mixt. with N(4)-(6-chloro-2-methoxy-9-acridinyl)-N(1),N(1)-diethyl-1,4-pentanediamine dihydrochloride  *Quinacrine *Ethosuximide Drug Combinations.

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy