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Quipazine

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Definition: A pharmacologic congener of serotonin that contracts smooth muscle and has actions similar to those of tricyclic antidepressants. It has been proposed as an oxytocic.     
Pharmacological Action Antidepressive Agents, Second-Generation; Oxytocics; Serotonin Receptor Agonists 		Other names MA1291; MA 1291; Quipazine Maleate (1:1); Quipazine Maleate; Quipazine Hydrochloride; MA-1291; 2-(1-Piperazinyl)quinoline
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5-methyl-6-nitroquipazine  0   Quipazine/*analogs & derivatives Carbon Radioisotopes Ligands. Nucl Med Biol 2002 Aug;29(6):651-6
3'-methyl-6-nitroquipazine  0   Quipazine/*analogs & derivatives. Bioorg Med Chem Lett 2000 Dec 4;10(23):2643-6
2'-methyl-6-nitroquipazine  0   Quipazine/*analogs & derivatives. Bioorg Med Chem Lett 2000 Dec 4;10(23):2643-6
5-bromo-6-nitroquipazine  0   Quipazine/*analogs & derivatives. Nucl Med Biol 1999 Jul;26(5):501-7
N-methylquipazine  0   Quipazine/*analogs & derivatives. Nucl Med Biol 1997 Jul;24(5):405-12
4-bromo-6-nitroquipazine  143954-73-8 Quinoline, 4-bromo-6-nitro-2-(1-piperazinyl)  Quipazine/*analogs & derivatives Receptors, Serotonin. Neuropharmacology 1992 Sep;31(9):869-74
6-bromoquipazine  124782-95-2 Quinoline, 6-bromo-2-(1-piperazinyl)  Quipazine/*analogs & derivatives Receptors, Serotonin. Neuropharmacology 1992 Sep;31(9):869-74
5-iodo-6-nitro-2-piperazinylquinoline  139593-11-6   Quipazine/*analogs & derivatives Iodine Radioisotopes Ligands. Eur J Pharmacol 1992 Jan 7;210(1):103-4
2-(4-(3-chloropropyl)piperazinyl)quinoline  111035-53-1   Quipazine/*analogs & derivatives. J Pharm Pharmacol 1990;42(7):522
6-nitroquipazine  77372-73-7 Quinoline, 6-nitro-2-(1-piperazinyl)  Quipazine/*analogs & derivatives.
Pharma Action Serotonin Antagonists 		Eur J Pharmacol 1981;70(2):195

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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