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RNA, Ribosomal, 23S

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Definition: Constituent of 50S subunit of prokaryotic ribosomes containing about 3200 nucleotides. 23S rRNA is involved in the initiation of polypeptide synthesis.  IM; /drug eff /ultrastruct permitted; DF: 23S RRNA    Other names 23S Ribosomal RNA; Ribosomal RNA, 23S; RNA, 23S Ribosomal
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
cethromycin  0   *Ketolides Protein Synthesis Inhibitors RNA, Ribosomal, 23S.
Pharma Action Anti-Bacterial Agents 		Antimicrob Agents Chemother 2000 Feb;44(2):447-9
telithromycin  0   *Ketolides Protein Synthesis Inhibitors RNA, Ribosomal, 23S.
Pharma Action Anti-Bacterial Agents 		Diagn Microbiol Infect Dis 1997 Jan-Feb;27(1-2):7-12; The Annals of Pharmacotherapy 2002 36:452-64KETEK
linezolid  165800-03-3   *Acetamides *Oxazolidinones RNA, Ribosomal, 23S.
Pharma Action Anti-Infective Agents ; Protein Synthesis Inhibitors 		J Med Chem 1996 Feb 2;39(3):673-9ZYVOX; LINEZOLID

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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