Ketolides (definition)

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Ketolides

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Definition: Compounds based on ERYTHROMYCIN with the 3-cladinose replaced by a ketone. They bind the 23S part of 70S bacterial RIBOSOMES.

Other names Erythromycins, 3 Keto; 3-Keto Erythromycins; 3 Keto Erythromycins; Erythromycins, 3-Keto; 3-Keto-Erythromycins

Substance	Categories	Source	Drugs*
JNJ 17155528	Naphthyridines Ketolides.	Antimicrob Agents Chemother 2005 Jan;49(1):309-15
JNJ 17155437	Naphthyridines Ketolides.	Antimicrob Agents Chemother 2005 Jan;49(1):309-15
3-deoxy-3-oxo-erythronolide B	*Ketolides.	Sheng Wu Gong Cheng Xue Bao 2002 Jan;18(2):198-203
TE-802	*Ketolides.	J Antibiot (Tokyo) 2001 Aug;54(8):664-78
cethromycin	Ketolides Protein Synthesis Inhibitors RNA, Ribosomal, 23S. Pharma Action* Anti-Bacterial Agents	Antimicrob Agents Chemother 2000 Feb;44(2):447-9
telithromycin	Ketolides Protein Synthesis Inhibitors RNA, Ribosomal, 23S. Pharma Action* Anti-Bacterial Agents	Diagn Microbiol Infect Dis 1997 Jan-Feb;27(1-2):7-12; The Annals of Pharmacotherapy 2002 36:452-64	KETEK
RU 64004	*Ketolides.	Antimicrob Agents Chemother 1997 Feb;41(2):454-9
3-keto-6-O-methylerythromycin A 11,12-cyclic carbazate	*Ketolides.	J Antibiot (Tokyo) 1996 May;49(5):465-77

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor

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