encyclopedia of medical concepts
ψ
ψ
Sincalide
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Definition
: An octapeptide hormone present in the intestine and brain. When secreted from the gastric mucosa, it stimulates the release of bile from the gallbladder and digestive enzymes from the pancreas.
do not confuse with Sincaline (
See Also
Appetite Depressants
;
Gastrointestinal Agents
Other names
Cholecystokinin Octapeptide; CCK-
8; SQ19844; SQ19,844; SQ 19844; SQ 19,844; Cholecystokinin Pancreozymin C Terminal Octapeptid; Syncalide; SQ-
19844; SQ-
19,844; OP-
CCK; Kinevac; H-
Asp-
Tyr(SO3H)-
Met-
Gly-
Trp-
Met-
Asp-
Phe-
NH2; Cholecystokinin Pancreozymin C-
Terminal Octapeptid; CCK-
OP; Bracco Brand of Sincalide
Drugs
*
:
KINEVAC
Substance
CAS Registry & name
Categories
Source
Drugs
*
indium DTPA-
Glu-
G-
CCK8
0
Pentetic Acid/*analogs & derivatives
Sincalide/*analogs & derivatives.
J Nucl Med 2004 Mar;45(3):485-94
cholecystokinin (26-
33) sulfated amide
0
*Peptide Fragments
Sincalide/*analogs & derivatives.
Diabetes 2001 Nov;50(11):2505-13
cholecystokinin (26-
32), rhodamine-
Tyr-
Gly-
Nle(28,31) phenethyl ester
0
*Rhodamines
Sincalide/*analogs & derivatives.
Am J Physiol 1999 Mar;276(3 Pt 1):C539-C547
AR C15849KF
0
Sincalide/*analogs & derivatives.
J Pharm Biomed Anal 1998 Aug;17(4-5):793-800
cholecystokinin (26-
33), I-
Tyr-
Gly-
(Nle(28,31),4-
NO2-
Phe(33))
118643-58-6
*Peptide Fragments
Sincalide/*analogs & derivatives.
Anal Biochem 1994 Aug 1;220(2):434-5
8-
sulfocholecystokinin octapeptide
0
Sincalide/*analogs & derivatives
Receptors, Cholecystokinin/agonists.
Pharma Action
Nootropic Agents
Peptides 1994;15(4):689-97
FPL 14294
154132-95-3 L-
Phenylalaninamide, N-
((4-
(sulfooxy)phenyl)acetyl)-
L-
methionylglycyl-
L-
tryptophyl-
L-
methionyl-
L-
alpha-
aspartyl-
Nalpha-
methyl
Sincalide/*analogs & derivatives.
Pharmacol Biochem Behav 1994 Mar;47(3):701-8
SUT 8701
123577-73-1 L-
Phenylalaninamide, N-
((1,1-
dimethylethoxy)carbonyl)-
O-
(dimethylphosphinyl)-
L-
tyrosyl-
L-
norleucylglycyl-
L-
tryptophyl-
L-
norleucyl-
L-
alpha-
aspartyl
Sincalide/*analogs & derivatives.
Jpn J Pharmacol 1993 Apr;61(4):341-9
JMV 332
130582-12-6 L-
Phenylalaninamide, N2-
acetyl-
N6-
(3-
carboxy-
1-
oxopropyl)-
L-
lysylglycyl-
L-
tryptophyl-
L-
lysyl-
L-
alpha-
aspartyl-
, cyclic (1-
4)-
peptide
Sincalide/*analogs & derivatives.
Peptides 1992 Nov-Dec;13(6):1227-32
desulfated sincalide
25679-24-7
Sincalide/*analogs & derivatives.
Surgery 1993 Feb;113(2):155-62
JMV 320
130582-10-4
Sincalide/*analogs & derivatives.
Ann Surg 1992 May;215(5):528-35
SNF 8906
137442-15-0
*Peptide Fragments
Sincalide/*analogs & derivatives.
Proc west Pharmacol Soc 1991;34:477-84
SNF 8814
137442-16-1
*Peptide Fragments
Sincalide/*analogs & derivatives.
Proc West Pharmacol Soc 1991;34:453-9
sincalide, Phe(CH2SO3Na)(2)
0
Sincalide/*analogs & derivatives.
Int J Pept Protein Res 1991;37(4):331
JMV 179
119386-87-7 L-
Aspartic acid, N-
(N-
(N-
(N-
(N-
(N-
((1,1-
dimethylethoxy)carbonyl)-
O-
sulfo-
L-
tyrosyl)-
L-
norleucyl)glycyl)-
D-
tryptophyl)-
L-
norleucyl)-
, 1-
(2-
phenylethyl) ester
Sincalide/*analogs & derivatives.
Pancreas 1991;6(3):275
JMV 167
120775-49-7 L-
alpha-
Asparagine, N2-
(N-
(N-
(N-
(N-
(N-
((1,1-
dimethylethoxy)carbonyl)-
O-
sulfo-
L-
tyrosyl)-
L-
norleucyl)glycyl)-
D-
tryptophyl)-
L-
norleucyl)-
N-
(2-
phenylethyl)
Sincalide/*analogs & derivatives.
Pancreas 1991;6(3):275
propionyl CCK octapeptide sulfate
0
Sincalide/*analogs & derivatives.
J Pharmacol Exp Ther 1991;257(3):1076
cholecystokinin (26-
32), Tyr-
Gly-
Nle(28,31) phenethyl ester
119400-92-9
*Peptide Fragments
Sincalide/*analogs & derivatives.
Mol Pharmacol 1991;39(2):150
JMV 170
117829-60-4 L-
alpha-
Asparagine, N2-
(N-
(N-
(N-
(N-
(N-
((1,1-
dimethylethoxy)carbonyl)-
O-
sulfo-
L-
tyrosyl)-
L-
norleucyl)glycyl)-
L-
tryptophyl)-
L-
norleucyl)-
N-
(2-
phenylethyl)
Sincalide/*analogs & derivatives.
Peptides 1990;11(5):873
SNF 8702
129228-52-0
*Peptide Fragments
Sincalide/*analogs & derivatives.
J Pharmacol Exp Ther 1990;255(3):1278
sincalide, pGlu
96693-35-5
Pyrrolidonecarboxylic Acid/*analogs & derivatives
Sincalide/*analogs & derivatives.
Physiol Behav 1990;47(5):911
JMV 236
113137-57-8
*Peptide Fragments
Sincalide/*analogs & derivatives.
Peptides 1989;10(5):1041
tert-
butyloxycarbonylcholecystokinin-
8
27220-86-6
Sincalide/*analogs & derivatives.
Mol Pharmacol 1989;36(4):647
JMV 182
0
Sincalide/*analogs & derivatives.
Am J Physiol 1989;257(4 Pt 1):G594
JMV 81
113282-22-7
Sincalide/*analogs & derivatives.
Am J Physiol 1989;257(4 Pt 1):G594
JMV 180
119733-42-5
Sincalide/*analogs & derivatives.
Biochim Biophys Acta 1989;1010(2):145
cholecystokinin (26-
33), Tyr-
Gly-
(Nle(28,31),4-
NO2-
Phe(33))
115136-01-1
*Peptide Fragments
Sincalide/*analogs & derivatives.
J Biol Chem 1988;263(11):5295
Bolton Hunter-
cholecystokinin nonapeptide
117829-67-1
*Succinimides
Sincalide/*analogs & derivatives.
Am J Physiol 1988;254(2 Pt 1):G176
succinyl-
tyrosyl-
methionyl-
glycyl-
tryptophyl-
methionyl-
aspartyl-
phenethylamide
112118-16-8
Sincalide/*analogs & derivatives.
Methods Find Exp Clin Pharmacol 1987;9(7):429
cholecystokinin (26-
33), I-
Tyr-
Gly-
Nle(28,31)
118688-24-7
*Peptide Fragments
Sincalide/*analogs & derivatives.
J Biol Chem 1987;262(28):13850
t-
butyloxycarbonyl-
(sulfo-
Tyr)-
Met-
Gly-
Trp-
Nle-
Asp 2-
phenylethyl ester
109525-32-8
Sincalide/*analogs & derivatives.
J Biol Chem 1987;262(15):7226
(3-
azido-
4-
hydroxy-
5-
iodobenzimidyl)-
CCK-
8
0
*Azides
Sincalide/*analogs & derivatives
Iodine Radioisotopes.
Pancreas 1987;2(1):79
N-
(4-
(4'-
azido-
3'-
iodophenylazo)benzoyl)-
3-
aminopropionyl-
CCK-
8
0
*Azides
Sincalide/*analogs & derivatives
Iodine Radioisotopes.
Pancreas 1987;2(1):79
cholecystokinin (26-
33), N-
acetyl-
norleucine(28,31)
105504-60-7
*Peptide Fragments
Sincalide/*analogs & derivatives.
Life Sci 1986;39(18):1623
cholecystokinin (26-
33), N-
alpha-
hydroxysulfonyl-
Nle(28,31)
105483-63-4
*Peptide Fragments
Sincalide/*analogs & derivatives.
Life Sci 1986;39(18):1623
cholecystokinin hexapeptide
21163-42-8
*Peptide Fragments
*Sincalide.
Biopolymers 1985;24(9):1663
cholecystokinin pentapeptide
18917-24-3
*Peptide Fragments
*Sincalide.
Biopolymers 1985;24(9):1663
cholecystokinin (27-
33), t-
butyloxycarbonyl
20987-59-1
*Peptide Fragments
Sincalide/*analogs & derivatives.
Neuropeptides 1986;7(1):1
cholecystokinin (27-
33), tert-
butyloxycarbonyl-
Nle(28,31)
98640-66-5
*Peptide Fragments
Sincalide/*analogs & derivatives.
Life Sci 1985;37(26):2483
Bolton Hunter-
cholecystokinin octapeptide
0
*Succinimides
Sincalide/*analogs & derivatives.
Pharma Action
Indicators and Reagents
J Pharmacol Exp Ther 1985;232(3):775
cholecystokinin (26-
33)
80980-81-0
Sincalide/*analogs & derivatives.
Am J Physiol 1985;248(1 Pt 1):G98
cholecystokinin (26-
32)
0
Sincalide/*analogs & derivatives.
Am J Physiol 1984;246(3 pt 1):G292
cholecystokinin octapeptide, des-