Definition: A protein present in the cell wall of most Staphylococcus aureus strains. The protein selectively binds to the Fc region of human normal and myeloma-derived IMMUNOGLOBULIN G. It elicits antibody activity and may cause hypersensitivity reactions due to histamine release; has also been used as cell surface antigen marker and in the clinical assessment of B lymphocyte function.
/drug eff /ultrastruct permitted; DF: STAPH PROTEIN A
Other names Protein A; Protein A, Staphylococcal; A, Staphylococcal Protein; A, Protein