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Ricin

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Definition: A protein phytotoxin from the seeds of Ricinus communis, the castor oil plant. It agglutinates cells, is proteolytic, and causes lethal inflammation and hemorrhage if taken internally.  /antag: consider also ANTITOXINS   
Pharmacological Action Chemical Warfare Agents 		Other names Lectin, Ricinus; Lectin, Castor Bean; Castor Bean Lectin; Toxin, Ricinus; Ricinus Lectin; B Chain, Ricin; A Chain, Ricin; Ricinus Toxin; Ricin I; Ricin D; Ricin B Chain; Ricin A Chain; RCA 60; RCA60
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
CNL protein, Clitocybe nebularis  0   *Ricin. Immunology. 2011 Dec;134(4):409-18
RiVax  0   *Vaccines Ricin. Proc Natl Acad Sci U S A 2006 Feb 14;103(7):2268-73
peptide P3  0   *Peptides *Carrier Proteins Ricin. Biotechnol Lett 2003 Oct;25(19):1671-5
924-RAC  0   *Ricin *Antibodies, Monoclonal Immunotoxins. Methods Mol Biol 2001;166:277-94
DA7 immunotoxin  0   *Ricin *Antibodies, Monoclonal Immunotoxins. Methods Mol Biol 2001;166:17-29
anti-B4 blocked ricin immunoconjugate  0   *Ricin *Immunoconjugates. Clin Cancer Res 1998 Nov;4(11):2599-604
RFT5-SMPT-dgA immunotoxin  0   *Ricin *Antibodies, Monoclonal *Immunoconjugates. Leukemia Lymphoma 1998 Aug;30(5-6):525-37
ricin A-GnRH conjugate  0   *Ricin *Gonadotropin-Releasing Hormone. Endocrinology 1994 Dec;135(6):2742-8
ZENECA ZD0490  158319-44-9   *Antibodies *Ricin Immunotoxins. Cancer Res 1994 Sep 1;54(17):4684-90
peroxidase-labelled Ricinus communis agglutinin  0   *Ricin *Peroxidases Castor Bean. J Hirnforsch 1993;34(4):493-501
N901 MoAb-blocked ricin conjugate  0   *Ricin *Antibodies, Monoclonal *Immunoconjugates Immunotoxins. Chest 1993 Apr;103(4 Suppl):436S-39S
Oncolysin B  0   *Ricin *Antibodies, Monoclonal *Immunoconjugates Immunotoxins. Oncology (Williston Park) 1992 Sep;6(9):94
proricin  0   *Protein Precursors *Ricin Castor Bean. Bioconjug Chem 1992 Sep-Oct;3(5):375-81
CD4-ricin A chain conjugate  0   *Ricin *Antigens, CD4 Recombinant Proteins. Bioconj Chem 1990;1(1):24
zolimomab aritox  141483-72-9   *Ricin *Antibodies, Monoclonal Immunotoxins Graft vs Host Disease. JAMA 1991;265(16):2041
T101 FAB fragment-ricin A-chain immunotoxin  0   *Ricin *Immunoglobulin Fab Fragments Immunotoxins. Bone Marrow Transplant 1989;4(4):367
XomaZyme  0   *Antibodies, Monoclonal *Ricin Immunotoxins. Transplantation Proc 1989;21(1 Pt 3):3004
staphylococcal protein A-ricin A fusion protein, recombinant  0   *Recombinant Fusion Proteins *Ricin *Staphylococcal Protein A. Gene 1988;68(2):315
wheat germ agglutinin-ricin A-chain conjugate  0   *Ricin *Wheat Germ Agglutinins Neurotoxins. Brain Res 1986;377(2):221
preproricin  0   *Ricin *Protein Precursors Castor Bean. Eur J Biochem 1985;148(2):265
epidermal growth factor-ricin complex  0   *Epidermal Growth Factor *Ricin. Biochem Biophys Res Commun 1984;124(2):551
modeccin A-chain-ricin B-chain hybrid toxin  0   *Ricin *Ribosome Inactivating Proteins, Type 2 Toxins, Biological. Biochim Biophys Acta 1983;761(3):296

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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