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Strophanthins

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Definition: A number of different cardioactive glycosides obtained from Strophanthus species. OUABAIN is from S. gratus and CYMARINE from S. kombe. They are used like the digitalis glycosides.  cardiac glycosides   
Pharmacological Action Cardiotonic Agents; Enzyme Inhibitors
Examples Cymarine; Ouabain; Strophanthidin 		Other names Strophanthin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
technetium Tc 99m K-strophanthin-beta  0   *Strophanthins *Organotechnetium Compounds. Int J Rad Appl Instrum (B) 1989;16(1):41
3-acetylstrophanthin  28146-52-3   *Strophanthins. J Physiol 1983;336:433
strophanthin K  11005-63-3   *Strophanthins.
Pharma Action Cardiotonic Agents 		Biull Eksp Biol Med 1981;91(1):35
helveticosol 3',4'-dinitrate  51943-33-0 (3 beta,5 beta)-3-((2,6-dideoxy-3,4-di-O- nitro-beta-D-ribo-hexopyranosyl)oxy)-5,14,19- trihydroxycard-20(22)-enolide  *Strophanthins Cardiac Glycosides Digitalis Glycosides. Arch Int Pharmacodyn Ther 239(2):270;1979
K-strophanthin-beta  560-53-2   *Strophanthins. Farmakol Toksikol 41(5):564;1978
K-strophanthoside  33279-57-1   *Strophanthins. J Pharmacol Exp Ther 189(1):185;1974
helveticoside  630-64-8 3-beta-5,14-trihydroxy-19-oxo-5-beta-card-20(22)- enolid-3-digitoxoside /OD/ K-Strophanthidin-3- digitoxoside /OD/ erysimin  *Digitalis Glycosides *Strophanthins. Farm Zh 31(5):47;1976; Farm Zh 6:52;1978
N-(4'-amino-n-butyl)-3-aminoacetylstrophanthidin  40520-83-0 Glycine, N-(4-aminobutyl)-, (3beta,5beta,14beta)-21,23-epoxy-5,14-dihydroxy-19,23-dioxo-24-norchol-20(22)-en-3-yl ester  *Strophanthins. J Biol Chem 247(23):7636;1972
convallatoxin  508-75-8   *Strophanthins.
Pharma Action Vasodilator Agents 		Farm Zh 1979;5:73; Farmatsiia 27(5):30;1978; Probl Endokrinol 24(5):29;1978; Voen Med Zh 9:78;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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