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Sugar Alcohol Dehydrogenases

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Definition: Reversibly catalyzes the oxidation of a hydroxyl group of sugar alcohols to form a keto sugar, aldehyde or lactone. Any acceptor except molecular oxygen is permitted. Includes EC 1.1.1.; EC 1.1.2. and EC 1.1.99.     
Examples Aldehyde Reductase; D-Xylulose Reductase; Glycerolphosphate Dehydrogenase; L-Gulonolactone Oxidase; L-Iditol 2-Dehydrogenase; Mannitol Dehydrogenases 		Other names Sugar Alcohol Oxidoreductases; Oxidoreductases, Sugar Alcohol; Dehydrogenases, Sugar Alcohol; Alcohol Oxidoreductases, Sugar; Alcohol Dehydrogenases, Sugar
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
IolX protein, Bacillus subtilis  EC 1.1.-   *Bacterial Proteins *Sugar Alcohol Dehydrogenases. Microbiology. 2010 May;156(Pt 5):1538-46
IolW protein, Bacillus subtilis  EC 1.1.-   *Bacterial Proteins *Sugar Alcohol Dehydrogenases. Microbiology. 2010 May;156(Pt 5):1538-46
Pentosuria  0   *Carbohydrate Metabolism, Inborn Errors Sugar Alcohol Dehydrogenases/deficiency Xylulose.
dTDP-4-dehydro-6-deoxyglucose reductase, Geobacillus tepidamans  EC 1.1.-   *Sugar Alcohol Dehydrogenases. Glycobiology 2007 Apr;17(4):433-43
D-arabitol phosphate dehydrogenase, Bacillus subtilis  EC 1.1.-   *Sugar Alcohol Dehydrogenases Organisms, Genetically Modified. Biotechnol J 2006 Feb;1(2):214-9
sorbose reductase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. Yeast 2005 Sep;22(12):957-69
2,3-diketo-L-gulonate reductase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases Escherichia coli Proteins. J Biol Chem 2004 Mar 26;279(13):13148-55
1,5-anhydro-D-glucitol dehydrogenase  EC 1.1.-   *Sugar Alcohol Dehydrogenases. Appl Environ Microbiol 2003 May;69(5);2603-7
L-arabinitol 4-dehydrogenase  EC 1.1.1.12   *Sugar Alcohol Dehydrogenases. J Biol Chem 2001 Nov 2;276(44):40631-7
thymidine diphosphate-6-deoxy-L-lyxo-4-hexulose reductase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. J Biol Chem 2000 Mar 10;275(10):6806-12
thymidine diphosphate-4-keto-6-deoxy-D-glucose reductase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. J Biol Chem 1999 Jun 11;274(24):16933-9
D-iditol 2-dehydrogenase  EC 1.1.1.15 D-iditol:NAD+ 2-oxidoreductase  *Sugar Alcohol Dehydrogenases.
1,5-anhydro-fructose reductase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. J Biochem (Tokyo) 1998 Jan;123(1):189-93
RibD protein, E coli  EC 3.5.4   *Nucleotide Deaminases *Sugar Alcohol Dehydrogenases *Escherichia coli Proteins. J Bacteriol 1997 Mar;179(6):2022-8
RibG protein, Bacillus subtilis  EC 3.5.4   *Bacterial Proteins *Nucleotide Deaminases *Sugar Alcohol Dehydrogenases Multienzyme Complexes. J Bacteriol 1997 Mar;179(6):2022-8
galactitol 2-dehydrogenase  EC 1.1.1.16   *Sugar Alcohol Dehydrogenases. Microbiology 1995 Aug;141( Pt 8):1865-73
levoglucosan dehydrogenase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. Biosci Biotechnol Biochem 1994 Dec;58(12):2193-6
D-arabinonolactone oxidase  EC 1.1.3.-   *Sugar Alcohol Dehydrogenases. Eur J Biochem 1994 Nov 1;225(3):1073-9
mannitol-mannose 1-oxidoreductase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. Arch Biochem Biophys 1992 Nov 1;298(2):612-9
mannose-6-phosphate reductase  EC 1.1.1.224   *Sugar Alcohol Dehydrogenases. Biotechniques 1992 May;12(5):660-6
L-ribose reductase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. J Bacteriol 1991;173(8):2459
N-acyl-D-mannosamine dehydrogenase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. J Biochem (Tokyo) 1988;104(3):466
2,5-diketo-D-gluconate 5-reductase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. J Biol Chem 1987;262(19):9016
guaiacylglycerol beta-O-4-guaiacyl ether dehydrogenase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. Biochimie 1985;67(9):973
3-deoxy-D-glycero-2,5-hexodiulosonate dehydrogenase  EC 1.1.1.127   *Sugar Alcohol Dehydrogenases. J Bacteriol 1985;162(2):708
ribitol-5-phosphate dehydrogenase  EC 1.1.1.137   *Sugar Alcohol Dehydrogenases. Adv Microb Physiol 1984;25:149
L-sorbose-1-phosphate reductase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. Methods Enzymol 1982;89(Pt D):248
glycerol oxidase  EC 1.1.3.-   *Sugar Alcohol Dehydrogenases. Methods Enzymol 1982;89(Pt D):243
xylitol 5-phosphate dehydrogenase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. J Bacteriol 1982;150(2):657
2,5-diamino-6-hydroxy-4-ribosylaminopyrimidine-5'-phosphate reductase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. Mikrobiologiia 1981;50(6):1008
L-galactitol-1-phosphate dehydrogenase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. Arch Biochem Biophys 1981;209(2):592
D-arabinose dehydrogenase  EC 1.1.1.116   *Sugar Alcohol Dehydrogenases. J Bacteriol 1981;145(1):164
glyceraldehyde reductase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. Lancet 1980;2(8207):1268
inositol NAD epimerase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. Biochem Biophys Res Commun 77(1):340;1977; Biochemistry 12(23):4705;1973
L-xylulose reductase  EC 1.1.1.10 xylitol NADP 4-oxidoreductase (L-xylulose-forming)  *Sugar Alcohol Dehydrogenases. Biochem J 149(3):553;1975; Diabetes 28(9):793;1979; Jpn J Clin Pathol 23(5):381;1975
D-erythritol 1-phosphate dehydrogenase  EC 1.1.1.- D-erythro-tetritol 1-phosphate NAD(+) 2-oxidoreductase  *Sugar Alcohol Dehydrogenases. J Bacteriol 124(1):391;1975
D-arabinitol dehydrogenase  EC 1.1.1.11   *Sugar Alcohol Dehydrogenases. Biochem J 183(1):31;1979; J Mol Biol 132(3):435;1979
sorbitol-6-phosphate dehydrogenase  EC 1.1.1.140   *Sugar Alcohol Dehydrogenases.
D-ribose reductase  EC 1.1.-   *Sugar Alcohol Dehydrogenases. Biochim Biophys Acta 385(1):51;1975
ribitol 2-dehydrogenase  EC 1.1.1.56   *Sugar Alcohol Dehydrogenases. Biochem J 183(1):31;1979; C R Acad Sci (D) (Paris) 284(20):2043;1978; Hoppe Seylers Z Physiol Chem 357:1169;1976; J Mol Biol 132(3):435;1979
phosphoribosylaminopyrimidine reductase  EC 1.1.1.- 5-amino-2,6-dioxy-4-(5'-phosphoribosylamino) pyrimidine reductase  *Sugar Alcohol Dehydrogenases. J Bacteriol 136(2):657;1978
acylglycerone-phosphate reductase  EC 1.1.1.101   *Sugar Alcohol Dehydrogenases. J Neurochem 31:125;1978
myo-inositol-1-phosphate dehydrogenase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. J Biol Chem 254(18):8717;1979
mannitol-1-phosphate dehydrogenase  EC 1.1.1.17   *Sugar Alcohol Dehydrogenases. Biochem J 149(3):553;1975; Hoppe Seylers Z Physiol Chem 357:1163;1976
2-keto-3-deoxy-L-fuconate-NAD oxidoreductase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. J Biol Chem 250(16):6185;1975; J Biol Chem 254(15):7060;1979
myo-inositol 2-dehydrogenase  EC 1.1.1.18   *Sugar Alcohol Dehydrogenases. Biochim Biophys Acta 293(2):295;1973; J Biol Chem 254(16):7684;1979; Tanpakushitsu Kakusan Koso 24(7):953;1979
glycerol 2-dehydrogenase (NADP+)  EC 1.1.1.156   *Sugar Alcohol Dehydrogenases. Eur J Biochem 75(2):423,423;1977
glycerol dehydrogenase  EC 1.1.1.6   *Sugar Alcohol Dehydrogenases. Chem Pharm Bull (Tokyo) 26(3):716;1978; Clin Chim Acta 89(3):447;1978; J Bacteriol 1980;141(3):1077; J Biol Chem 249(10):3132;1974
L-galactonolactone oxidase  EC 1.3.3.24   *Sugar Alcohol Dehydrogenases. Arch Biochem Biophys 191(2):479;1978; FEBS Lett 97(1):40;1979
D-erythrulose reductase  EC 1.1.1.162   *Sugar Alcohol Dehydrogenases. J Biochem (Tokyo) 1980;87(1):47; J Biochem (Tokyo) 75(2):333;1974; J Biochem (Tokyo) 78(3):519;1975; J Biochem (Tokyo) 85(4):1003;1979
dTDP-dihydrostreptose synthase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. Biochim Biophys Acta 568(1):243;1979
cinerulose reductase  EC 1.1.1.-   *Sugar Alcohol Dehydrogenases. Biochem Biophys Res Commun 82(1):188;1978; Gann 1979;70(4):395

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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