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Tetrabenazine

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Definition: A drug formerly used as an antipsychotic and treatment of various movement disorders. Tetrabenazine blocks neurotransmitter uptake into adrenergic storage vesicles and has been used as a high affinity label for the vesicle transport system.     
Pharmacological Action Adrenergic Uptake Inhibitors 		Other names Tetrabenazine Orphan Brand; Xenazine; Shire Brand of Tetrabenazine; Roche Brand of Tetrabenazine; Orphan Brand of Tetrabenazine; Nitoman; Cambridge Laboratories Brand of TetrabenazineDrugs* : XENAZINE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
9-fluoroethyldihydrotetrabenazine  0   Tetrabenazine/*analogs & derivatives Fluorine Radioisotopes. Nucl Med Biol 2010 Apr;37(3):357-63
9-fluoropropyldihydrotetrabenazine  0   Tetrabenazine/*analogs & derivatives Fluorine Radioisotopes. Nucl Med Biol 2010 Feb;37(2):133-41
2-N-((3'-iodo-4'-azidophenyl)propionyl)tetrabenazine  0   *Azides Tetrabenazine/*analogs & derivatives Iodine Radioisotopes. J Biol Chem 1997 Oct 10;272(41):26049-55
5-O-methyldihydrotetrabenazine  152404-97-2   Tetrabenazine/*analogs & derivatives Carbon Radioisotopes. Appl Radiat Isot 1993 Dec;44(12):1487-9
N-(3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo(a)quinolizin-2-yl)-4-((4-azido-2-nitrophenyl)amino)butanamide  96557-41-4   *Azides Tetrabenazine/*analogs & derivatives. Biochemistry 1985;24(14):3660
dihydrotetrabenazine  3466-75-9   Tetrabenazine/*analogs & derivatives. C R Acad Sci (D) (Paris) 1981;293(4):221

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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