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Thymopoietins

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Definition: Two closely related polypeptides (molecular weight 7,000) isolated from the thymus gland. These hormones induce the differentiation of prothymocytes to thymocytes within the thymus. They also cause a delayed impairment of neuromuscular transmission in vivo and are therefore believed to be the agent responsible for myasthenia gravis.  /biosyn /physiol permitted; do not confuse X ref THYMINS with THYMINE   
Examples Thymopentin 		Other names TP 49; II, Thymopoietin; I, Thymopoietin; Thymopoietin II; Thymopoietin I; TP-49; Thymins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
lamina-associated polypeptide 2, zebrafish  0   *Thymopoietins *Zebrafish Proteins. J Cell Sci 2003 Jun 15;116(Pt 12):2505-17
thymopoietin II, 4-fluoro-Phe(3)  0   *Thymopoietins. Mediators Inflamm 2000;9(3-4):201-6
thymopoietin II, Nal(3)  0   *Thymopoietins. Mediators Inflamm 2000;9(3-4):201-6
TMPO protein, human  157298-12-9   *Nuclear Proteins *Thymopoietins Membrane Proteins. Genomics 1995 Jul 20;28(2):198-205
thymopoietin-related peptide precursor  0   *Protein Precursors *Thymopoietins. Biochem Mol Biol Int 1994 Nov;34(5):927-33
cyclo(arginyl-prolyl-aspartyl-valyl-tyrosyl)  135680-82-9   *Peptides, Cyclic *Thymopoietins. Drug Des Deliv 1990;6(3):213
berlopentin  91418-71-2   *Peptide Fragments *Thymopoietins. Arch Geschwulstforsch 1989;59(3):161
N-acetylsplenopeptin  120834-20-0   *Peptide Fragments *Thymopoietins. Bioorg Khim 1989;15(4):453
splenotritin  105803-00-7 L-Glutamic acid, N-(N2-L-arginyl-L-lysyl)  *Peptide Fragments *Thymopoietins. Biomed Biochim Acta 1986;45(10):149
thymopoietin, Cys (28-39)  106939-01-9   *Peptide Fragments *Thymopoietins. Cell Immunol 1986;100(2):305
thymocartin  85466-18-8 L-Valine, N-(N-(N2-L-arginyl-L-lysyl)-L-alpha-aspartyl)  *Peptide Fragments *Thymopoietins. J Immunopharmacol 1985;7(1):67
thymopoietin (38-45)  95034-35-8 L-Threonine, N-(N-(N-(N2-(N-(N-(N-L-alpha-glutamyl-L-leucyl)-L-tyrosyl)-L-leucyl)-L-glutaminyl)-L-seryl)-L-leucyl)-, (2S-(2alpha,5alpha,6beta))  *Peptide Fragments *Thymopoietins. Regul Pept 1984;9(3):155
splenopentin  75957-60-7   *Peptide Fragments *Thymopoietins. Transplantation 1984;38(1):52
thymopoietin II octadecapeptide (32-49)  84979-67-9 L-Arginine, L-arginyl-L-lysyl-L-alpha-aspartyl-L-valyl-L-tyrosyl-L-valyl-L-alpha-glutamyl-L-leucyl-L-tyrosyl-L-leucyl-L-glutaminyl-L-seryl-L-leucyl-L-threonyl-L-alanyl-L-leucyl-L-lysyl  *Peptide Fragments *Thymopoietins. Chem Pharm Bull (Tokyo) 1982;30(9):3271
thymopoietin III  79103-34-7 Thymopoietin II, 34-L-glutamic acid-43-L-histidine  *Thymopoietins Lymphokines Spleen.
Pharma Action Adjuvants, Immunologic ; Antitubercular Agents 		Biochemistry 1981;20(21):6195; Farm Zh 5:67;1977; Kosm Biol Aviakosm Med 12(1):81;1978

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